FN3KRP

FN3KRP
Identifiers
Aliases	FN3KRP , FN3KL, fructosamine 3 kinase related protein
External IDs	OMIM: 611683 MGI: 2679256 HomoloGene: 11093 GeneCards: FN3KRP
Gene location (Human)
Chr.	Chromosome 17 (human)
End	82,730,328 bp
Gene location (Mouse)
Chr.	Chromosome 11 (mouse)
End	121,322,114 bp
RNA expression pattern
	Top expressed in
	amygdala; ; prefrontal cortex; ; Brodmann area 9; ; putamen; ; nucleus accumbens; ; caudate nucleus; ; skin of abdomen; ; cerebellar hemisphere; ; transverse colon; ; tibial nerve;
	Top expressed in
	mirror; ; bone marrow; ; cerebellar cortex; ; hippocampus proper; ; superior frontal gyrus; ; kidney; ; spermatocyte; ; ganglionic eminence; ; olfactory bulb; ; hypothalamus;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	transferase activity ; kinase activity ;
Cellular component	cytosol ;
Biological process	post-translational protein modification ; phosphorylation ;
	Sources:Amigo / QuickGO
Orthologs
	79672
	238024
	ENSG00000141560
	ENSMUSG00000039253
	Q9HA64
	Q8K274
	NM_024619
	NM_181420
	NP_078895
	NP_852085
	Wikidata
View/Edit Human	View/Edit Mouse

Last updated August 30, 2022

Ketosamine-3-kinase is an enzyme that in humans is encoded by the FN3KRP (fructosamine-3-kinase-related-protein) gene.^[5]^[6]

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References

1 2 3 GRCh38: Ensembl release 89: ENSG00000141560 - Ensembl, May 2017
1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000039253 - Ensembl, May 2017
↑ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ Collard F, Delpierre G, Stroobant V, Matthijs G, Van Schaftingen E (Nov 2003). "A mammalian protein homologous to fructosamine-3-kinase is a ketosamine-3-kinase acting on psicosamines and ribulosamines but not on fructosamines". Diabetes. 52 (12): 2888–95. doi: 10.2337/diabetes.52.12.2888 . PMID 14633848.
↑ "Entrez Gene: FN3KRP fructosamine-3-kinase-related protein".

Wiemann S, Weil B, Wellenreuther R, et al. (2001). "Toward a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs". Genome Res. 11 (3): 422–35. doi:10.1101/gr.GR1547R. PMC 311072 . PMID 11230166.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi: 10.1073/pnas.242603899 . PMC 139241 . PMID 12477932.
Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi: 10.1038/ng1285 . PMID 14702039.
Collard F, Wiame E, Bergans N, et al. (2005). "Fructosamine 3-kinase-related protein and deglycation in human erythrocytes". Biochem. J. 382 (Pt 1): 137–43. doi:10.1042/BJ20040307. PMC 1133924 . PMID 15137908.
Conner JR, Beisswenger PJ, Szwergold BS (2004). "The expression of the genes for fructosamine-3-kinase and fructosamine-3-kinase-related protein appears to be constitutive and unaffected by environmental signals". Biochem. Biophys. Res. Commun. 323 (3): 932–6. doi:10.1016/j.bbrc.2004.08.181. PMID 15381090.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928 . PMID 15489334.
Conner JR, Beisswenger PJ, Szwergold BS (2005). "Some clues as to the regulation, expression, function, and distribution of fructosamine-3-kinase and fructosamine-3-kinase-related protein". Ann. N. Y. Acad. Sci. 1043: 824–36. Bibcode:2005NYASA1043..824C. doi:10.1196/annals.1333.095. PMID 16037310. S2CID 19916880.
Szwergold B, Manevich Y, Payne L, Loomes K (2007). "Fructosamine-3-kinase-related-protein phosphorylates glucitolamines on the C-4 hydroxyl: novel substrate specificity of an enigmatic enzyme". Biochem. Biophys. Res. Commun. 361 (4): 870–5. doi:10.1016/j.bbrc.2007.07.127. PMID 17686456.

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[refGRCh38Ensembl-1] 1 2 3 GRCh38: Ensembl release 89: ENSG00000141560 - Ensembl, May 2017

[refGRCm38Ensembl-2] 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000039253 - Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid14633848-5] Collard F, Delpierre G, Stroobant V, Matthijs G, Van Schaftingen E (Nov 2003). "A mammalian protein homologous to fructosamine-3-kinase is a ketosamine-3-kinase acting on psicosamines and ribulosamines but not on fructosamines". Diabetes. 52 (12): 2888–95. doi: 10.2337/diabetes.52.12.2888 . PMID 14633848.

[entrez-6] "Entrez Gene: FN3KRP fructosamine-3-kinase-related protein".

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FN3KRP

Related Research Articles

References

Further reading