Hypoxia is a condition in which the body or a region of the body is deprived of adequate oxygen supply at the tissue level. Hypoxia may be classified as either generalized, affecting the whole body, or local, affecting a region of the body. Although hypoxia is often a pathological condition, variations in arterial oxygen concentrations can be part of the normal physiology, for example, during strenuous physical exercise.
Retinopathy is any damage to the retina of the eyes, which may cause vision impairment. Retinopathy often refers to retinal vascular disease, or damage to the retina caused by abnormal blood flow. Age-related macular degeneration is technically included under the umbrella term retinopathy but is often discussed as a separate entity. Retinopathy, or retinal vascular disease, can be broadly categorized into proliferative and non-proliferative types. Frequently, retinopathy is an ocular manifestation of systemic disease as seen in diabetes or hypertension. Diabetes is the most common cause of retinopathy in the U.S. as of 2008. Diabetic retinopathy is the leading cause of blindness in working-aged people. It accounts for about 5% of blindness worldwide and is designated a priority eye disease by the World Health Organization.
Diabetic retinopathy, is a medical condition in which damage occurs to the retina due to diabetes. It is a leading cause of blindness in developed countries and one of the lead causes of sight loss in the world, even though there are many new therapies and improved treatments for helping people live with diabetes.
The g-force or gravitational force equivalent is mass-specific force, expressed in units of standard gravity . It is used for sustained accelerations, that cause a perception of weight. For example, an object at rest on Earth's surface is subject to 1 g, equaling the conventional value of gravitational acceleration on Earth, about 9.8 m/s2. More transient acceleration, accompanied with significant jerk, is called shock.
A g-suit, or anti-g suit, is a flight suit worn by aviators and astronauts who are subject to high levels of acceleration force (g). It is designed to prevent a black-out and g-LOC caused by the blood pooling in the lower part of the body when under acceleration, thus depriving the brain of blood. Black-out and g-LOC have caused a number of fatal aircraft accidents.
Retinal detachment is a disorder of the eye in which the retina peels away from its underlying layer of support tissue. Initial detachment may be in a very small region, but without rapid treatment the entire retina may detach, leading to vision loss and blindness. It is a surgical emergency.
An uncontrolled decompression is an undesired drop in the pressure of a sealed system, such as a pressurised aircraft cabin or hyperbaric chamber, that typically results from human error, structural failure, or impact, causing the pressurised vessel to vent into its surroundings or fail to pressurize at all.
Retinal hemorrhage is a disorder of the eye in which bleeding occurs in the retina, the light sensitive tissue, located on the back wall of the eye. There are photoreceptor cells in the retina called rods and cones, which transduce light energy into nerve signals that can be processed by the brain to form visual images. Retinal hemorrhage is strongly associated with child abuse in infants and young children and often leaves such abused infants permanently blind. In older children and adults, retinal hemorrhage can be caused by several medical conditions such as hypertension, retinal vein occlusion, anemia, leukemia or diabetes.
A hypobaric chamber, or altitude chamber, is a chamber used during aerospace or high terrestrial altitude research or training to simulate the effects of high altitude on the human body, especially hypoxia and hypobaria. Some chambers also control for temperature and relative humidity.
Photopsia is the presence of perceived flashes of light in the field of vision.
Freediving blackout, breath-hold blackout, or apnea blackout is a class of hypoxic blackout, a loss of consciousness caused by cerebral hypoxia towards the end of a breath-hold dive, when the swimmer does not necessarily experience an urgent need to breathe and has no other obvious medical condition that might have caused it. It can be provoked by hyperventilating just before a dive, or as a consequence of the pressure reduction on ascent, or a combination of these. Victims are often established practitioners of breath-hold diving, are fit, strong swimmers and have not experienced problems before. Blackout may also be referred to as a syncope or fainting.
Coats' disease is a rare congenital, nonhereditary eye disorder, causing full or partial blindness, characterized by abnormal development of blood vessels behind the retina. Coats' disease can also fall under glaucoma.
A greyout is a transient loss of vision characterized by a perceived dimming of light and color, sometimes accompanied by a loss of peripheral vision. It is a precursor to fainting or a blackout and is caused by hypoxia, often due to a loss of blood pressure.
A redout occurs when the body experiences a negative g-force sufficient to cause a blood flow from the lower parts of the body to the head. It is the inverse effect of a greyout, where blood flows away from the head to the lower parts of the body. Usually, a redout will only ever be experienced by pilots, as planes are the most common devices that allow such negative g-forces to be exerted. Redouts are potentially dangerous and can cause retinal damage and hemorrhagic stroke.
Optic neuropathy is damage to the optic nerve from any cause. The optic nerve is a bundle of millions of fibers in the retina that sends visual signals to the brain.
High-g training is done by aviators and astronauts who are subject to high levels of acceleration ('g'). It is designed to prevent a g-induced loss of consciousness (g-LOC), a situation when the action of g-forces moves the blood away from the brain to the extent that consciousness is lost. Incidents of acceleration-induced loss of consciousness have caused fatal accidents in aircraft capable of sustaining high-g for considerable periods.
Retinal migraine is a retinal disease often accompanied by migraine headache and typically affects only one eye. It is caused by ischaemia or vascular spasm in or behind the affected eye.
Vascular occlusion is a blockage of a blood vessel, usually with a clot. It differs from thrombosis in that it can be used to describe any form of blockage, not just one formed by a clot. When it occurs in a major vein, it can, in some cases, cause deep vein thrombosis. The condition is also relatively common in the retina, and can cause partial or total loss of vision. An occlusion can often be diagnosed using Doppler sonography.
The RAF Centre of Aviation Medicine is a medical organisation run by the Royal Air Force and based at RAF Henlow in Bedfordshire. It is the main organisation conducting aviation medicine research in the UK.
A choke-out is a hand-to-hand combat tactic involving the use of a chokehold to cause syncope, or temporary loss of consciousness, at which point the choke is released. Common chokeholds in grappling used to accomplish a choke-out include the rear naked choke, arm triangle, triangle choke, and the guillotine.
