GHS hazard statements

Hazard statements form part of the Globally Harmonized System of Classification and Labelling of Chemicals (GHS). They are intended to form a set of standardized phrases about the hazards of chemical substances and mixtures that can be translated into different languages. ^{[a] [b]} As such, they serve the same purpose as the well-known R-phrases, which they are intended to replace.

Hazard statements are one of the key elements for the labelling of containers under the GHS, along with: ^[1]

• an identification of the product
• one or more hazard pictograms (where necessary)
• a signal word – either Danger or Warning – where necessary
• precautionary statements, indicating how the product should be handled to minimize risks to the user (as well as to other people and the general environment)
• the identity of the supplier (who might be a manufacturer or importer).

Each hazard statement is designated a code, starting with the letter H and followed by three digits. Statements which correspond to related hazards are grouped together by code number, so the numbering is not consecutive. The code is used for reference purposes, for example to help with translations, but it is the actual phrase which should appear on labels and safety data sheets. ^[2]

Physical hazards

v t e GHS H-phrases (42) [3]
Code	Phrase
H200	(Obsolete) Unstable explosive.
H201	(Obsolete) Explosive: mass explosion hazard.
H202	(Obsolete) Explosive: severe projection hazard.
H203	(Obsolete) Explosive: fire, blast or projection hazard.
H204	Fire or projection hazard.
H205	(Obsolete) May mass explode in fire.
H206	Fire, blast or projection hazard: increased risk of explosion if desensitizing agent is reduced.
H207	Fire or projection hazard; increased risk of explosion if desensitizing agent is reduced.
H208	Fire hazard; increased risk of explosion if desensitizing agent is reduced.
H209	Explosive.
H210	Very explosive.
H211	May be sensitive.
H220	Extremely flammable gas.
H221	Flammable gas.
H222	Extremely flammable aerosol.
H223	Flammable aerosol.
H224	Extremely flammable liquid and vapour.
H225	Highly flammable liquid and vapour.
H226	Flammable liquid and vapour.
H227	Combustible liquid.
H228	Flammable solid.
H229	Pressurized container: may burst if heated.
H230	May react explosively even in the absence of air.
H231	May react explosively even in the absence of air at elevated pressure and/or temperature.
H232	May ignite spontaneously if exposed to air.
H240	Heating may cause an explosion.
H241	Heating may cause a fire or explosion.
H242	Heating may cause a fire.
H250	Catches fire spontaneously if exposed to air.
H251	Self-heating: may catch fire.
H252	Self-heating in large quantities: may catch fire.
H260	In contact with water releases flammable gases which may ignite spontaneously.
H261	In contact with water releases flammable gas.
H270	May cause or intensify fire: oxidizer.
H271	May cause fire or explosion: strong oxidizer.
H272	May intensify fire: oxidizer.
H280	Contains gas under pressure: may explode if heated.
H281	Contains refrigerated gas: may cause cryogenic burns or injury.
H282	Extremely flammable chemical under pressure: May explode if heated.
H283	Flammable chemical under pressure: May explode if heated.
H284	Chemical under pressure: May explode if heated.
H290	May be corrosive to metals.

Health hazards

v t e GHS H-phrases (62) [3]
Code	Phrase
H300	Fatal if swallowed.
H300+H310	Fatal if swallowed or in contact with skin.
H300+H310+H330	Fatal if swallowed, in contact with skin or if inhaled.
H300+H330	Fatal if swallowed or if inhaled.
H301	Toxic if swallowed.
H301+H311	Toxic if swallowed or in contact with skin.
H301+H311+H331	Toxic if swallowed, in contact with skin or if inhaled.
H301+H331	Toxic if swallowed or if inhaled.
H302	Harmful if swallowed.
H302+H312	Harmful if swallowed or in contact with skin.
H302+H312+H332	Harmful if swallowed, in contact with skin or if inhaled.
H302+H332	Harmful if swallowed or inhaled.
H303	May be harmful if swallowed.
H303+H313	May be harmful if swallowed or in contact with skin.
H303+H313+H333	May be harmful if swallowed, in contact with skin or if inhaled.
H303+H333	May be harmful if swallowed or if inhaled.
H304	May be fatal if swallowed and enters airways.
H305	May be harmful if swallowed and enters airways.
H310	Fatal in contact with skin.
H310+H330	Fatal in contact with skin or if inhaled.
H311	Toxic in contact with skin.
H311+H331	Toxic in contact with skin or if inhaled.
H312	Harmful in contact with skin.
H312+H332	Harmful in contact with skin or if inhaled.
H313	May be harmful in contact with skin.
H313+H333	May be harmful in contact with skin or if inhaled.
H314	Causes severe skin burns and eye damage.
H315	Causes skin irritation.
H315+H319	Causes skin irritation and serious eye irritation.
H315+H320	Causes skin and eye irritation.
H316	Causes mild skin irritation.
H317	May cause an allergic skin reaction.
H318	Causes serious eye damage.
H319	Causes serious eye irritation.
H320	Causes eye irritation.
H330	Fatal if inhaled.
H331	Toxic if inhaled.
H332	Harmful if inhaled.
H333	May be harmful if inhaled.
H334	May cause allergy or asthma symptoms of breathing difficulties if inhaled.
H335	May cause respiratory irritation.
H336	May cause drowsiness or dizziness.
H340	May cause genetic defects.
H341	Suspected of causing genetic defects.
H350	May cause cancer.
H350i	May cause cancer by inhalation.
H351	Suspected of causing cancer.
H360	May damage fertility or the unborn child.
H360D	May damage the unborn child.
H360Df	May damage the unborn child. Suspected of damaging fertility.
H360F	May damage fertility.
H360FD	May damage fertility. May damage the unborn child.
H360Fd	May damage fertility. Suspected of damaging the unborn child.
H361	Suspected of damaging fertility or the unborn child.
H361d	Suspected of damaging the unborn child.
H361f	Suspected of damaging fertility.
H361fd	Suspected of damaging fertility. Suspected of damaging the unborn child.
H362	May cause harm to breast-fed children.
H370	Causes damage to organs.
H371	May cause damage to organs.
H372	Causes damage to organs through prolonged or repeated exposure.
H373	May cause damage to organs through prolonged or repeated exposure.

Environmental hazards

v t e GHS H-phrases (10) [3]
Code	Phrase
H400	Very toxic to aquatic life.
H401	Toxic to aquatic life.
H402	Harmful to aquatic life.
H410	Very toxic to aquatic life with long lasting effects.
H411	Toxic to aquatic life with long lasting effects.
H412	Harmful to aquatic life with long lasting effects.
H413	May cause long lasting harmful effects to aquatic life.
H420	Harms public health and the environment by destroying ozone in the upper atmosphere.
H421	Harms public health and the environment by contributing to global warming.
H441	(Obsolete) Very toxic to terrestrial invertebrates.

Region-specific hazard statements

European Union

The European Union has implemented the GHS through the CLP Regulation. Nevertheless, the older system based on the Dangerous Substances Directive was used in parallel until June 2015. Some R-phrases which do not have simple equivalents under the GHS have been retained under the CLP Regulation: ^[4] the numbering mirrors the number of the previous R-phrase.

Physical properties

• EUH006: Explosive with or without contact with air, deleted in the fourth adaptation to technical progress of CLP.
• EUH014: Reacts violently with water
• EUH018: In use may form flammable/explosive vapour-air mixture
• EUH019: May form explosive peroxides
• EUH044: Risk of explosion if heated under confinement

Health properties

• EUH029: Contact with water liberates toxic gas
• EUH031: Contact with acids liberates toxic gas
• EUH032: Contact with acids liberates very toxic gas
• EUH066: Repeated exposure may cause skin dryness or cracking
• EUH070: Toxic by eye contact
• EUH071: Corrosive to the respiratory tract
• EUH380: May cause endocrine disruption in humans
• EUH381: Suspected of causing endocrine disruption in humans

Environmental properties

• EUH059: Hazardous to the ozone layer, superseded by GHS Class 5.1 in the second adaptation to technical progress of CLP.
• EUH430: May cause endocrine disruption in the environment
• EUH431: Suspected of causing endocrine disruption in the environment
• EUH440: Accumulates in the environment and living organisms including in humans
• EUH441: Strongly accumulates in the environment and living organisms including in humans
• EUH450: Can cause long-lasting and diffuse contamination of water resources
• EUH451: Can cause very long-lasting and diffuse contamination of water resources

Other EU hazard statements

Some other hazard statements intended for use in very specific circumstances have also been retained under the CLP Regulation. ^[5] In this case, the numbering of the EU specific hazard statements can coincide with GHS hazard statements if the "EU" prefix is not included.

• EUH201: Contains lead. Should not be used on surfaces liable to be chewed or sucked by children.
  • EUH201A: Warning! Contains lead.
• EUH202: Cyanoacrylate. Danger. Bonds skin and eyes in seconds. Keep out of the reach of children.
• EUH203: Contains chromium(VI). May produce an allergic reaction.
• EUH204: Contains isocyanates. May produce an allergic reaction.
• EUH205: Contains epoxy constituents. May produce an allergic reaction.
• EUH206: Warning! Do not use together with other products. May release dangerous gases (chlorine).
• EUH207: Warning! Contains cadmium. Dangerous fumes are formed during use. See information supplied by the manufacturer. Comply with the safety instructions.
• EUH208: Contains <name of sensitising substance>. May produce an allergic reaction.
• EUH209: Can become highly flammable in use.
  • EUH209A: Can become flammable in use.
• EUH210: Safety data sheet available on request.
• EUH211: Warning! Hazardous respirable droplets may be formed when sprayed. Do not breathe spray or mist.
• EUH212: Warning! Hazardous respirable dust may be formed when used. Do not breathe dust.
• EUH401: To avoid risks to human health and the environment, comply with the instructions for use.

Australia

The GHS was adopted in Australia from 1 January 2012 and becomes mandatory in States and Territories that have adopted the harmonised Work Health and Safety laws (other than Victoria and Western Australia) as of 1 January 2017. ^[6] The National Code of Practice for the Preparation of Safety Data Sheets for Hazardous Chemicals ^[7] includes 12 Australian-specific GHS Hazard Statements, as follows:

Physical hazard statements

• AUH001: Explosive without moisture
• AUH006: Explosive with or without contact with air
• AUH014: Reacts violently with water
• AUH018: In use, may form a flammable/explosive vapor-air mixture
• AUH019: May form explosive peroxides
• AUH044: Risk of explosion if heated under confinement

Human health hazard statements

• AUH029: Contact with water liberates toxic gas
• AUH031: Contact with acids liberates toxic gas

Additional non-GHS hazard statements

• AUH032: Contact with acids liberates very toxic gas
• AUH066: Repeated exposure may cause skin dryness or cracking
• AUH070: Toxic by eye contact
• AUH071: Corrosive to the respiratory tract

New Zealand

As of March 2009, the relevant New Zealand regulations under the Hazardous Substances and New Organisms Act 1996 do not specify the exact wording required for hazard statements. However, the New Zealand classification system includes three categories of environmental hazard which are not included in the GHS Rev.2:

• Ecotoxicity to soil environment
• Ecotoxicity to terrestrial vertebrates
• Ecotoxicity to terrestrial invertebrates

These are classes 9.2–9.4 respectively of the New Zealand classification scheme, and are divided into subclasses according to the degree of hazard. ^[8] Substances in subclass 9.2D ("Substances that are slightly harmful in the soil environment") do not require a hazard statement, while substances in the other subclasses require an indication of the general degree of hazard and general type of hazard. ^[9]

Notes

1. The United Nations has published the list of GHS hazard statements in all UN official languages (Arabic, Chinese, English, French, Russian, Spanish): it can be found in Annex 3 of GHS Rev.2 for the corresponding language.
2. A list of translations into all the European Union official languages can be found in Annex III to the CLP Regulation, on pages 146–91 of the official English-language version for the GHS statements and pages 192–209 for the EU-specific statements.

References

Citations

1. Part 1, section 1.4.10.5.2, GHS Rev.2
2. Part 1, section 1.4.10.5.2(b)(ii), GHS Rev.2
3. "Globally Harmonized System of Classification and Labelling of Chemicals (GHS)" (pdf). Geneva: United Nations. 2025. Annex 3: Codification of hazard statements, codification and use of precautionary statements, codification of hazard pictograms and examples of precautionary pictograms (pp. 293–408).
4. Annex III, CLP Regulation, pp. 192–200.
5. Annex III, CLP Regulation, pp. 200–9.
6. "Hazardous chemicals including Globally Harmonised System of Classification and Labelling of Chemicals (GHS)". Safe Work Australia. Archived from the original on 2017-04-26. Retrieved 2016-09-30.
7. Preparation_of_Safety_Data_Sheet_for_Hazardous_Chemicals: Code of Practice (PDF). Safe Work Australia. February 2016. Archived from the original (PDF) on 2017-03-04. Retrieved 2016-09-30.
8. Schedule 6, Hazardous Substances (Classification) Regulations 2001
9. reg. 20, Hazardous Substances (Identification) Regulations 2001

Works cited

• Globally Harmonized System of Classification and Labelling of Chemicals (Fourth revised ed.), New York and Geneva: United Nations, 2011, ISBN   978-92-1-117042-9, ST/SG/AC.10/30/Rev.2 ("GHS Rev.4")
• Globally Harmonized System of Classification and Labelling of Chemicals (Second revised ed.), New York and Geneva: United Nations, 2007, ISBN   978-92-1-116957-7, ST/SG/AC.10/30/Rev.2 ("GHS Rev.2")
• Hazardous Substances (Classification) Regulations 2001 (SR 2001/113) (New Zealand)
• Hazardous Substances (Identification) Regulations 2001 (SR 2001/124) (New Zealand)
• "Regulation (EC) No 1272/2008 of the European Parliament and of the Council of 16 December 2008 on classification, labelling and packaging of substances and mixtures, amending and repealing Directives 67/548/EEC and 1999/45/EC, and amending Regulation (EC) No 1907/2006", OJCE (L353): 1–1355, 2008-12-31 (the "CLP Regulation")

External links

• Chemical Hazard & Precautionary Phrases in 23 European Languages, machine-readable and versioned