Gladys Block

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Gladys Block is a nutrition researcher who worked at the National Cancer Institute.

Contents

Education and career

From July 1991 onward, Block worked at the University of California, Berkeley as a professor (and subsequently professor emerita) of Community Health and Human Development in the School of Public Health. [1] [2]

In 1993 she founded NutritionQuest which produces assessments of diet and physical activity for researchers. [3]

Block FFQ

During her time at the National Cancer Institute (1982 to 1991), Block developed a semi-quantitative food frequency questionnaire (FFQ) that would later come to be known as the Block FFQ. [4] The approach to questionnaire design was first described in a paper co-authored with Hartman, Dresser, Carroll, Gannon, and Gardner in 1986. [5] Research by Block, Potosky, and Clifford on validation of the questionnaire was published in 1990. [6]

After leaving the National Cancer Institute in 1991, Block continued to work on the FFQ, offering it through the company, NutritionQuest, that she founded in 1993. Subsequent released versions include the Block 95 and Block 98 FFQs. A web version was also released and validated. [7]

The Block FFQ has been used in third-party research [8] and has also been the subject of validation and comparison studies. [9] [10] [11]

The Block FFQ is the earliest of the currently widely used FFQs in the United States. Other semi-quantitative FFQs include the Diet History Questionnaire (DHQ) and NHANES (also developed at the National Cancer Institute) and the Harvard FFQ, developed by a team at Harvard University led by Walter Willett. [4] [12]

Work

Vitamins

In 1992, Block's review of 15 epidemiological studies on cancer rates and intake of Vitamin C was mentioned in the New York Times . [13]

Block has been cited in media coverage of the debate around the efficacy of dietary multivitamin supplements in combating health risks including the risk of cancer, obesity, diabetes, heart disease, and hypertension. Others taking a similar position as Block (in favor of dietary supplements) include Harvard professor Walter Willett (designer of the Harvard FFQ), researcher Bruce N. Ames, and Michael Jacobson of the Center for Science in the Public Interest. Those on the other side include Marion Nestle, Joan Gussow, Catherine Wotecki, Walter Mertz, and Edgar Miller. [14] [15] [16]

Variety in diet

Block has led research on the variety in people's diet and its effects on people's nutrient consumption and health status. [17] She has been cited on the subject in the New York Times . [18]

Alive!

Block has developed a program called ALIVE that people can use to improve their diet and physical activity. [19] [20] The program and its spinoff, ALIVE-PD (to help prediabetics prevent diabetes) are currently offered through Turnaround Health, a division of NutritionQuest. [21] [22]


Related Research Articles

Fat Esters of three fatty acid chains and the alcohol glycerol, one of the three main macronutrients, also known as triglycerides

In nutrition, biology, and chemistry, fat usually means any ester of fatty acids, or a mixture of such compounds; most commonly those that occur in living beings or in food.

Vitamin Nutrients required by organisms in small amounts

A vitamin is an organic molecule (or a set of molecules closely related chemically, i.e. vitamers) that is an essential micronutrient which an organism needs in small quantities for the proper functioning of its metabolism. Essential nutrients cannot be synthesized in the organism, either at all or not in sufficient quantities, and therefore must be obtained through the diet. Vitamin C can be synthesized by some species but not by others; it is not a vitamin in the first instance but is in the second. The term vitamin does not include the three other groups of essential nutrients: minerals, essential fatty acids, and essential amino acids. Most vitamins are not single molecules, but groups of related molecules called vitamers. For example, there are eight vitamers of vitamin E: four tocopherols and four tocotrienols. Some sources list fourteen vitamins, by including choline, but major health organizations list thirteen: vitamin A (as all-trans-retinol, all-trans-retinyl-esters, as well as all-trans-beta-carotene and other provitamin A carotenoids), vitamin B1 (thiamine), vitamin B2 (riboflavin), vitamin B3 (niacin), vitamin B5 (pantothenic acid), vitamin B6 (pyridoxine), vitamin B7 (biotin), vitamin B9 (folic acid or folate), vitamin B12 (cobalamins), vitamin C (ascorbic acid), vitamin D (calciferols), vitamin E (tocopherols and tocotrienols), and vitamin K (phylloquinone and menaquinones).

Dietary fiber portion of plant-derived food that cannot be completely digested

Dietary fiber or roughage is the portion of plant-derived food that cannot be completely broken down by human digestive enzymes. Dietary fibers are diverse in chemical composition, and can be grouped generally by their solubility, viscosity, and fermentability, which affect how fibers are processed in the body. Dietary fiber has two main components: soluble fiber and insoluble fiber, which are components of plant foods, such as legumes, whole grains and cereals, vegetables, fruits, and nuts or seeds. A diet high in regular fiber consumption is generally associated with supporting health and lowering the risk of several diseases.

A saturated fat is a type of fat in which the fatty acid chains have all or predominantly single bonds. A fat is made of two kinds of smaller molecules: glycerol and fatty acids. Fats are made of long chains of carbon (C) atoms. Some carbon atoms are linked by single bonds (-C-C-) and others are linked by double bonds (-C=C-). Double bonds can react with hydrogen to form single bonds. They are called saturated because the second bond is broken and each half of the bond is attached to a hydrogen atom.

Mediterranean diet Diet inspired by 1960s eating habits of Greece, Italy, and Spain

The Mediterranean diet is a diet inspired by the eating habits of Greece, Italy, and Spain in the 1960s. The principal aspects of this diet include proportionally high consumption of olive oil, legumes, unrefined cereals, fruits, and vegetables, moderate to high consumption of fish, moderate consumption of dairy products, moderate wine consumption, and low consumption of non-fish meat products. Olive oil has been studied as a potential health factor for reducing all-cause mortality and the risk of chronic diseases.

The China–Cornell–Oxford Project, short for the "China-Oxford-Cornell Study on Dietary, Lifestyle and Disease Mortality Characteristics in 65 Rural Chinese Counties," was a large observational study conducted throughout the 1980s in rural China, a partnership between Cornell University, the University of Oxford, and the government of China. The study compared the health consequences of diets rich in animal-based foods to diets rich in plant-based foods among people who were genetically similar. In May 1990, The New York Times termed the study "the Grand Prix of epidemiology".

Multivitamin Dietary supplement containing vitamins

A multivitamin is a preparation intended to serve as a dietary supplement with vitamins, dietary minerals, and other nutritional elements. Such preparations are available in the form of tablets, capsules, pastilles, powders, liquids, or injectable formulations. Other than injectable formulations, which are only available and administered under medical supervision, multivitamins are recognized by the Codex Alimentarius Commission as a category of food.

The glycemic load (GL) of food is a number that estimates how much the food will raise a person's blood glucose level after eating it. One unit of glycemic load approximates the effect of eating one gram of glucose. Glycemic load accounts for how much carbohydrate is in the food and how much each gram of carbohydrate in the food raises blood glucose levels. Glycemic load is based on the glycemic index (GI), and is calculated by multiplying the grams of available carbohydrate in the food by the food's glycemic index, and then dividing by 100.

Healthy diet Diet that helps maintain or improve general health

A healthy diet is a diet that helps maintain or improve overall health. A healthy diet provides the body with essential nutrition: fluid, macronutrients, micronutrients, and adequate food energy.

Megavitamin therapy is the use of large doses of vitamins, often many times greater than the recommended dietary allowance (RDA) in the attempt to prevent or treat diseases. Megavitamin therapy is typically used in alternative medicine by practitioners who call their approach orthomolecular medicine. Vitamins are useful in preventing and treating illnesses specifically associated with dietary vitamin shortfalls, but the conclusions of medical research are that the broad claims of disease treatment by advocates of megavitamin therapy are unsubstantiated by the available evidence. It is generally accepted that doses of any vitamin greatly in excess of nutritional requirements will result either in toxicity or in the excess simply being metabolised; thus evidence in favour of vitamin supplementation supports only doses in the normal range. Critics have described some aspects of orthomolecular medicine as food faddism or even quackery. Research on nutrient supplementation in general suggests that some nutritional supplements might be beneficial, and that others might be harmful; several specific nutritional therapies are associated with an increased likelihood of the condition they are meant to prevent.

The Nurses' Health Study is a series of prospective studies that examine epidemiology and the long-term effects of nutrition, hormones, environment, and nurses' work-life on health and disease development. The studies have been among the largest investigations into risk factors for major chronic diseases ever conducted. The Nurses' Health Studies have led to many insights on health and well-being, including cancer prevention, cardiovascular disease, and type 2 diabetes. They have included clinicians, epidemiologists, and statisticians at the Channing Laboratory, Harvard Medical School, Harvard School of Public Health, and several Harvard-affiliated hospitals, including Brigham and Women's Hospital, Dana–Farber Cancer Institute, Children's Hospital Boston, and Beth Israel Deaconess Medical Center.

Walter C. Willett, is an American physician and nutrition researcher. Currently, Willett is the Fredrick John Stare Professor of Epidemiology and Nutrition at the Harvard School of Public Health and was the chair of its department of nutrition from 1991 to 2017. He is also a professor of medicine at Harvard Medical School.

Diet and cancer Connections between dietary habits and cancer

Dietary factors are recognized as having a significant effect on the risk of cancers, with different dietary elements both increasing and reducing risk. Diet and obesity may be related to up to 30-35% of cancer deaths, while physical inactivity appears to be related to 7% risk of cancer occurrence. One review in 2011 suggested that total caloric intake influences cancer incidence and possibly progression.

Western pattern diet Modern dietary pattern

The Western pattern diet (WPD) is a modern dietary pattern that is generally characterized by high intakes of red meat, processed meat, pre-packaged foods, butter, candy and sweets, fried foods, conventionally-raised animal products, high-fat dairy products, eggs, refined grains, potatoes, corn and high-sugar drinks, and low intakes of fruits, vegetables, whole grains, grass-fed animal products, fish, nuts, and seeds. The modern standard American diet was brought about by fundamental lifestyle changes following the Neolithic Revolution, and, later, the Industrial Revolution.

Food frequency questionnaire (FFQ) is a dietary assessment tool delivered as a questionnaire to estimate frequency and, in some cases, portion size information about food and beverage consumption over a specified period of time, typically the past month, three months, or year. FFQs are a common dietary assessment tool used in large epidemiologic studies of nutrition and health. Examples of usage include assessment of intake of vitamins and other nutrients, assessment of the intake of toxins, and estimating the prevalence of dietary patterns such as vegetarianism.

Nutritional epidemiology Field of medical research on disease and diet

Nutritional epidemiology examines dietary and nutritional factors in relation to disease occurrence at a population level. Nutritional epidemiology is a relatively new field of medical research that studies the relationship between nutrition and health. It is a young discipline in epidemiology that is continuing to grow in relevance to present-day health concerns. Diet and physical activity are difficult to measure accurately, which may partly explain why nutrition has received less attention than other risk factors for disease in epidemiology. Nutritional epidemiology uses knowledge from nutritional science to aid in the understanding of human nutrition and the explanation of basic underlying mechanisms. Nutritional science information is also used in the development of nutritional epidemiological studies and interventions including clinical, case-control and cohort studies. Nutritional epidemiological methods have been developed to study the relationship between diet and disease. Findings from these studies impact public health as they guide the development of dietary recommendations including those tailored specifically for the prevention of certain diseases, conditions and cancers. It is argued by western researchers that nutritional epidemiology should be a core component in the training of all health and social service professions because of its increasing relevance and past successes in improving the health of the public worldwide. However, it is also argued that nutritional epidemiological studies yield unreliable findings as they rely on the role of diet in health and disease, which is known as an exposure that is susceptible to considerable measurement error.

The Seven Countries Study is an epidemiological longitudinal study directed by Ancel Keys at what is today the University of Minnesota Laboratory of Physiological Hygiene & Exercise Science (LPHES). Begun in 1956 with a yearly grant of US$200,000 from the U.S. Public Health Service, the study was first published in 1978 and then followed up on its subjects every five years thereafter.

Vegan nutrition Nutritional and human health aspects of vegan diets

Vegan nutrition refers to the nutritional and human health aspects of vegan diets. A well-planned, balanced vegan diet is suitable to meet all recommendations for nutrients in every stage of human life. Vegan diets tend to be higher in dietary fiber, magnesium, folic acid, vitamin C, vitamin E, iron, and phytochemicals; and lower in calories, saturated fat, cholesterol, long-chain omega-3 fatty acids, vitamin D, calcium, zinc, and vitamin B12. Researchers agree that those on a vegan diet should eat foods fortified with vitamin B12 or take a dietary supplement. Preliminary evidence from epidemiological research indicates that a vegan diet may lower the risk of cancer.

Frank Hu

Frank B. Hu is a Chinese American nutrition and diabetes researcher. He is Chair of the Department of Nutrition and the Fredrick J. Stare Professor of Nutrition and Epidemiology at the Harvard T.H. Chan School of Public Health, and Professor of Medicine at the Harvard Medical School.

A 24-hour diet recall is a dietary assessment tool that consists of a structured interview in which participants are asked to recall all food and drink they have consumed in the previous 24 hours. It may be self-administered.

References

  1. "Gladys Block PhD". School of Public Health, University of California, Berkeley . Retrieved October 25, 2016.
  2. "Gladys Blcock: Expert Profile". Center for Health Journalism . Retrieved October 25, 2016.
  3. "NutritionQuest: Company". NutritionQuest. Retrieved June 27, 2020.
  4. 1 2 "Food Frequency Questionnaires" (PDF). University of Colorado Denver . Retrieved September 20, 2016.
  5. Block, Gladys; Hartman, AM; Dresser, CM; Carroll, MD; Gannon, J; Gardner, L (1986). "A data-based approach to diet questionnaire design and testing". American Journal of Epidemiology . 124 (3): 453–469. doi:10.1093/oxfordjournals.aje.a114416. PMID   3740045.
  6. Block, Gladys; Wood, M; Potosky, A; Clifford, C (1990). "Validation of a self-administered diet history questionnaire using multiple diet records". Journal of Clinical Epidemiology . 43 (12): 1327–1335. doi:10.1016/0895-4356(90)90099-B. PMID   2254769.
  7. "Our Research: Questionnaires". NutritionQuest. Retrieved October 26, 2016.
  8. Mares-Perlman, JA; Klein, BEK; Klein, R; Ritter, LL; Fisher, MR; Freudenheim, JL (1993). "A diet history questionnaire ranks nutrient intakes in middle-aged and older men and women similarly to multiple food records". Journal of Nutrition . 123 (3): 489–501. doi:10.1093/jn/123.3.489. PMID   8463852.
  9. Subar, Amy; Thompson, Frances; Kipnis, Victor; Midthune, Douglas; Hurwitz, Paul; McNutt, Suzanne; McIntosh, Anna; Rosenfeld, Simon (2001). "Comparative Validation of the Block, Willett, and National Cancer Institute Food Frequency Questionnaires: The Eating at America's Table Study". American Journal of Epidemiology . 154 (12): 1089–1099. doi: 10.1093/aje/154.12.1089 . PMID   11744511.
  10. Boucher, B; Cotterchio, M; Krieger, N; Nadalin, V; Block, Torin; Block, Gladys (2006). "Validity and reliability of the Block98 food-frequency questionnaire in a sample of Canadian women". Public Health Nutrition . 9 (1): 84–93. doi: 10.1079/phn2005763 . PMID   16480538.
  11. Johnson, BA; Herring, AH; Ibrahim, JG; Siega-Riz, Am (2007). "Structured measurement error in nutritional epidemiology; applications in the Pregnancy, Infection and Nutrition (PIN) Study". Journal of the American Statistical Association . 102 (479): 856–866. doi:10.1198/016214506000000771. PMC   2440718 . PMID   18584067.
  12. "Register of validated short dietary instruments (restricted to FFQs)". National Cancer Institute.
  13. "Vitamins Win Support as Potent Agents of Health". New York Times . March 10, 1992. Retrieved October 25, 2016.
  14. Burros, Marian (April 14, 1993). "Eating Well". New York Times . Retrieved October 25, 2016.
  15. "Eating Well". New York Times . April 20, 1994. Retrieved October 25, 2016.
  16. Kounang, Nadia (December 17, 2013). "Are multivitamins a waste of money? Editorial in medical journal says yes". CNN . Retrieved October 24, 2016.
  17. Kant, AK; Schatzkin, A; Harris, TB; Ziegler, RG; Block, Gladys (March 1, 1993). "Dietary diversity and subsequent mortality in the First National Health and Nutrition Examination Survey Epidemiologic Follow-up Study". American Journal of Clinical Nutrition . 57 (3): 434–440. doi:10.1093/ajcn/57.3.434. PMID   8382446.
  18. Hall, Trish (April 1, 1992). "Same Old Dinner, Same Old Lunch: Most People Like It That Way". New York Times . Retrieved October 25, 2016.
  19. Block, Gladys. "About Me". MedicineX, Stanford University.
  20. Sternfeld, B.; Block, C.; Quesenberry Jr, C. P.; Block, T. J.; Husson, G.; Norris, J. C.; Nelson, M.; Block, G. (2009). "Improving Diet and Physical Activity with ALIVE. A Worksite Randomized Trial". American Journal of Preventive Medicine . 36 (6): 475–483. doi:10.1016/j.amepre.2009.01.036. PMID   19460655.
  21. "About the Program". Turnaround Health. Retrieved October 26, 2016.
  22. "ALIVE! NutritionQuest" (PDF). National Institutes of Health, as part of the Commercialization Assistance Program, Small Business Innovation Research (SBIR). Retrieved October 26, 2016.