HIPK3

Last updated
HIPK3
Identifiers
Aliases HIPK3 , DYRK6, FIST3, PKY, YAK1, homeodomain interacting protein kinase 3
External IDs OMIM: 604424 MGI: 1314882 HomoloGene: 55923 GeneCards: HIPK3
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_001048200
NM_001278162
NM_001278163
NM_005734

NM_001145824
NM_010434

RefSeq (protein)

NP_001041665
NP_001265091
NP_001265092
NP_005725

NP_001139296
NP_034564

Location (UCSC) Chr 11: 33.26 – 33.36 Mb Chr 2: 104.26 – 104.32 Mb
PubMed search [3] [4]
Wikidata
View/Edit Human View/Edit Mouse

Homeodomain-interacting protein kinase 3 is an enzyme that in humans is encoded by the HIPK3 gene. [5] [6] [7]

Contents

Related Research Articles

<span class="mw-page-title-main">Caspase 10</span> Protein-coding gene in the species Homo sapiens

Caspase-10 is an enzyme that, in humans, is encoded by the CASP10 gene.

<span class="mw-page-title-main">MAP2K3</span> Protein-coding gene in the species Homo sapiens

Dual specificity mitogen-activated protein kinase kinase 3 is an enzyme that in humans is encoded by the MAP2K3 gene.

<span class="mw-page-title-main">HIPK2</span> Protein-coding gene in the species Homo sapiens

Homeodomain-interacting protein kinase 2 is an enzyme that in humans is encoded by the HIPK2 gene. HIPK2 can be categorized as a Serine/Threonine Protein kinase, specifically one that interacts with homeodomain transcription factors. It belongs to a family of protein kinases known as the DYRK kinases. Within this family HIPK2 belongs to a group of homeodomain-interacting protein kinases (HIPKs), including HIPK1 and HIPK3. HIPK2 can be found in a wide variety of species and its functions in gene expression and apoptosis are regulated by several different mechanisms.

<span class="mw-page-title-main">STK4</span> Protein-coding gene in the species Homo sapiens

Serine/threonine-protein kinase 4 is an enzyme that in humans is encoded by the STK4 gene.

<span class="mw-page-title-main">RPS6KA5</span> Enzyme

Ribosomal protein S6 kinase alpha-5 is an enzyme that in humans is encoded by the RPS6KA5 gene. This kinase, together with RPS6KA4, are thought to mediate the phosphorylation of histone H3, linked to the expression of immediate early genes.

<span class="mw-page-title-main">RPS6KA2</span> Enzyme found in humans

Ribosomal protein S6 kinase alpha-2 is an enzyme that in humans is encoded by the RPS6KA2 gene.

<span class="mw-page-title-main">Megakaryocyte-associated tyrosine kinase</span> Protein-coding gene in the species Homo sapiens

Megakaryocyte-associated tyrosine-protein kinase is an enzyme that in humans is encoded by the MATK gene.

<span class="mw-page-title-main">CAMK1</span> Protein-coding gene in the species Homo sapiens

Calcium/calmodulin-dependent protein kinase type 1 is an enzyme that in humans is encoded by the CAMK1 gene.

<span class="mw-page-title-main">PEA15</span> Protein-coding gene in the species Homo sapiens

Astrocytic phosphoprotein PEA-15 is a protein that in humans is encoded by the PEA15 gene.

<span class="mw-page-title-main">MKNK1</span> Protein-coding gene in the species Homo sapiens

MAP kinase-interacting serine/threonine-protein kinase 1 is an enzyme that in humans is encoded by the MKNK1 gene.

<span class="mw-page-title-main">PHOX2A</span> Protein-coding gene in the species Homo sapiens

Paired mesoderm homeobox protein 2A is a protein that in humans is encoded by the PHOX2A gene.

<span class="mw-page-title-main">DGKZ</span> Protein-coding gene in the species Homo sapiens

Diacylglycerol kinase zeta is an enzyme that in humans is encoded by the DGKZ gene.

<span class="mw-page-title-main">CDC42BPA</span> Protein-coding gene in the species Homo sapiens

Serine/threonine-protein kinase MRCK alpha is an enzyme that in humans is encoded by the CDC42BPA gene.

<span class="mw-page-title-main">GOLGA3</span> Protein-coding gene in the species Homo sapiens

Golgin subfamily A member 3 is a protein that in humans is encoded by the GOLGA3 gene.

<span class="mw-page-title-main">AKAP8</span> Protein-coding gene in the species Homo sapiens

A-kinase anchor protein 8 is an enzyme that, in humans, is encoded by the AKAP8 gene.

<span class="mw-page-title-main">SORBS3</span> Protein-coding gene in the species Homo sapiens

Vinexin is a protein that in humans is encoded by the SORBS3 gene.

<span class="mw-page-title-main">TAOK1</span> Protein-coding gene in the species Homo sapiens

Serine/threonine-protein kinase TAO1 is an enzyme that in humans is encoded by the TAOK1 gene.

<span class="mw-page-title-main">MAPKAPK5</span>

MAP kinase-activated protein kinase 5 is an enzyme that in humans is encoded by the MAPKAPK5 gene. The protein encoded by this gene is a member of the serine/threonine kinase family. In response to cellular stress and proinflammatory cytokines, this kinase is activated through its phosphorylation by MAP kinases, including MAPK1/ERK, MAPK14/p38-alpha, and MAPK11/p38-beta. In vitro, this kinase phosphorylates heat shock protein HSP27 at its physiologically relevant sites. Two alternately-spliced transcript variants of this gene encoding distinct isoforms have been reported.

<span class="mw-page-title-main">TP53INP1</span> Protein-coding gene in the species Homo sapiens

Tumor protein p53-inducible nuclear protein 1 is a protein that in humans is encoded by the TP53INP1 gene. In mice this protein is also called TRP53INP1 and is encoded by the Trp53inp1 gene. The protein is also referred to as SIP or "stress inducible protein"

<span class="mw-page-title-main">HIPK1</span> Protein-coding gene in the species Homo sapiens

Homeodomain-interacting protein kinase 1 is an enzyme that, in humans is encoded by the HIPK1 gene.

References

  1. 1 2 3 GRCh38: Ensembl release 89: ENSG00000110422 - Ensembl, May 2017
  2. 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000027177 - Ensembl, May 2017
  3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. Begley DA, Berkenpas MB, Sampson KE, Abraham I (Dec 1997). "Identification and sequence of human PKY, a putative kinase with increased expression in multidrug-resistant cells, with homology to yeast protein kinase Yak1". Gene. 200 (1–2): 35–43. doi:10.1016/S0378-1119(97)00350-8. PMID   9373137.
  6. Kim YH, Choi CY, Lee SJ, Conti MA, Kim Y (Nov 1998). "Homeodomain-interacting protein kinases, a novel family of co-repressors for homeodomain transcription factors". J Biol Chem. 273 (40): 25875–9. doi: 10.1074/jbc.273.40.25875 . PMID   9748262.
  7. "Entrez Gene: HIPK3 homeodomain interacting protein kinase 3".

Further reading