HNRPA3

HNRNPA3
Identifiers
Aliases	HNRNPA3 , 2610510D13Rik, D10S102, FBRNP, HNRPA3, heterogeneous nuclear ribonucleoprotein A3
External IDs	OMIM: 605372; MGI: 1917171; GeneCards: HNRNPA3; OMA:HNRNPA3 - orthologs
Gene location (Human) Chr. Chromosome 2 (human) [1] Band 2q31.2 Start 177,212,563 bp [1] End 177,223,958 bp [1]
Gene location (Mouse) Chr. Chromosome 2 (mouse) [2] Band 2|2 C3 Start 75,489,605 bp [2] End 75,499,751 bp [2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in ganglionic eminence ventricular zone right testis left testis monocyte Brodmann area 23 left ovary left lobe of thyroid gland right lobe of thyroid gland epithelium of colon Top expressed in tail of embryo neural layer of retina ventricular zone habenula dentate gyrus of hippocampal formation granule cell lobe of cerebellum cerebellar vermis superior cervical ganglion ureter substantia nigra More reference expression data BioGPS More reference expression data
Gene ontology Molecular function RNA transmembrane transporter activity protein binding mRNA binding nucleic acid binding RNA binding Cellular component cytoplasm messenger ribonucleoprotein complex neuron projection ribonucleoprotein granule catalytic step 2 spliceosome spliceosomal complex nucleus nucleoplasm postsynaptic density ribonucleoprotein complex Biological process mRNA splicing, via spliceosome mRNA processing mRNA transport RNA splicing RNA metabolic process Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 220988 229279 Ensembl ENSG00000170144 ENSMUSG00000059005 UniProt P51991 Q8BG05 RefSeq (mRNA) NM_001330247 NM_001330248 NM_001330249 NM_001330250 NM_001330251 NM_194247 NM_001395170 NM_053263 NM_146130 NM_198090 NM_001359971 RefSeq (protein) NP_001317176 NP_001317177 NP_001317178 NP_001317179 NP_001317180 NP_919223 NP_444493 NP_666242 NP_932758 NP_001346900 Location (UCSC) Chr 2: 177.21 – 177.22 Mb Chr 2: 75.49 – 75.5 Mb PubMed search [3] [4]
Wikidata
View/Edit Human View/Edit Mouse

Heterogeneous nuclear ribonucleoprotein A3 is a protein that in humans is encoded by the HNRNPA3 gene. ^{[5] [6] [7]}

References

1. GRCh38: Ensembl release 89: ENSG00000170144 – Ensembl, May 2017
2. GRCm38: Ensembl release 89: ENSMUSG00000059005 – Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. Ma AS, Moran-Jones K, Shan J, Munro TP, Snee MJ, Hoek KS, Smith R (May 2002). "Heterogeneous nuclear ribonucleoprotein A3, a novel RNA trafficking response element-binding protein". J Biol Chem. 277 (20): 18010–20. doi: 10.1074/jbc.M200050200 . PMID   11886857.
6. Makeyev AV, Kim CB, Ruddle FH, Enkhmandakh B, Erdenechimeg L, Bayarsaihan D (Mar 2005). "HnRNP A3 genes and pseudogenes in the vertebrate genomes". J Exp Zool A. 303 (4): 259–71. Bibcode:2005JEZA..303..259M. doi:10.1002/jez.a.164. PMID   15776420.
7. "Entrez Gene: HNRPA3 heterogeneous nuclear ribonucleoprotein A3".

Further reading

• Lairmore TC, Dou S, Howe JR, et al. (1993). "A 1.5-megabase yeast artificial chromosome contig from human chromosome 10q11.2 connecting three genetic loci (RET, D10S94, and D10S102) closely linked to the MEN2A locus". Proc. Natl. Acad. Sci. U.S.A. 90 (2): 492–6. Bibcode:1993PNAS...90..492L. doi: 10.1073/pnas.90.2.492 . PMC   45689 . PMID   8093642.
• Takiguchi S, Tokino T, Imai T, et al. (1993). "Identification and characterization of a cDNA, which is highly homologous to the ribonucleoprotein gene, from a locus (D10S102) closely linked to MEN2 (multiple endocrine neoplasia type 2)". Cytogenet. Cell Genet. 64 (2): 128–30. doi:10.1159/000133568. PMID   8101480.
• Jurica MS, Licklider LJ, Gygi SR, et al. (2002). "Purification and characterization of native spliceosomes suitable for three-dimensional structural analysis". RNA. 8 (4): 426–39. doi:10.1017/S1355838202021088. PMC   1370266 . PMID   11991638.
• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi: 10.1073/pnas.242603899 . PMC   139241 . PMID   12477932.
• Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC   528928 . PMID   15489334.
• Hillier LW, Graves TA, Fulton RS, et al. (2005). "Generation and annotation of the DNA sequences of human chromosomes 2 and 4". Nature. 434 (7034): 724–31. Bibcode:2005Natur.434..724H. doi: 10.1038/nature03466 . PMID   15815621.
• Kimura K, Wakamatsu A, Suzuki Y, et al. (2006). "Diversification of transcriptional modulation: Large-scale identification and characterization of putative alternative promoters of human genes". Genome Res. 16 (1): 55–65. doi:10.1101/gr.4039406. PMC   1356129 . PMID   16344560.
• Ewing RM, Chu P, Elisma F, et al. (2007). "Large-scale mapping of human protein–protein interactions by mass spectrometry". Mol. Syst. Biol. 3 (1): 89. doi:10.1038/msb4100134. PMC   1847948 . PMID   17353931.