IFT74

Last updated
IFT74
Identifiers
Aliases IFT74 , CCDC2, CMG-1, CMG1, intraflagellar transport 74, BBS20
External IDs OMIM: 608040 MGI: 1914944 HomoloGene: 11831 GeneCards: IFT74
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_001099222
NM_001099223
NM_001099224
NM_025103
NM_001349928

NM_001290568
NM_026319

RefSeq (protein)

NP_001092692
NP_001092693
NP_001092694
NP_079379
NP_001336857

NP_001277497
NP_080595

Location (UCSC) Chr 9: 26.95 – 27.07 Mb Chr 4: 94.61 – 94.69 Mb
PubMed search [3] [4]
Wikidata
View/Edit Human View/Edit Mouse

Intraflagellar transport protein 74 homolog (IFT74), also known as coiled-coil domain-containing protein 2 (CCDC2) and capillary morphogenesis gene 1 protein (CMG1), is a protein that in humans is encoded by the IFT74 gene. [5] [6]

BCMG1 is upregulated by umbilical vein endothelial cells during capillary morphogenesis. [6]

Related Research Articles

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PDXK

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MFN1

Mitofusin-1 is a protein that in humans is encoded by the MFN1 gene.

KRT78

Keratin, type II cytoskeletal 78 is a protein that in humans is encoded by the KRT78 gene.

NSL1

Kinetochore-associated protein NSL1 homolog is a protein that in humans is encoded by the NSL1 gene.

IFT57

Intraflagellar transport protein 57 homolog is a protein that in humans is encoded by the IFT57 gene.

SAV1

Protein salvador homolog 1 is a protein that in humans is encoded by the SAV1 gene.

HOOK3

Protein Hook homolog 3 is a protein that in humans is encoded by the HOOK3 gene.

FGF17

Fibroblast growth factor 17 is a protein that in humans is encoded by the FGF17 gene.

CTF8

Chromosome transmission fidelity protein 8 homolog is a protein that in humans is encoded by the CHTF8 gene.

VPS52

Vacuolar protein sorting-associated protein 52 homolog is a protein that in humans is encoded by the VPS52 gene.

IFT20

Intraflagellar transport protein 20 homolog is a protein that in humans is encoded by the IFT20 gene. The gene is composed of 6 exons and is located on human chromosome 17p11.1. This gene is expressed in human brain, lung, kidney and pancreas, and lower expression were also detected in human placenta, liver, thymus, prostate and testis.

KRT23

Keratin, type I cytoskeletal 23 is a protein that in humans is encoded by the KRT23 gene.

CCDC53 Protein-coding gene in the species Homo sapiens

Coiled-coil domain-containing protein 53 is a protein that in humans is encoded by the CCDC53 gene.

DNAJC11

DnaJ homolog subfamily C member 11 is a protein that in humans is encoded by the DNAJC11 gene.

Intraflagellar transport protein 46 homolog

Intraflagellar transport protein 46 homolog is a protein that in humans is encoded by the IFT46 gene.

HOXA2

Homeobox protein Hox-A2 is a protein that in humans is encoded by the HOXA2 gene.

IFT81

Intraflagellar transport protein 81 homolog is a protein that in humans is encoded by the IFT81 gene. Together with IFT74/72 it forms a core complex to build IFT particles which are required for cilium formation. Additionally, it interacts with basal body components as CEP170 which regulates the disassembly of the cilium.

IFT80

Intraflagellar transport protein 80 homolog (IFT80), also known as WD repeat-containing protein 56, is a protein that in humans is encoded by the IFT80 gene.

References

  1. 1 2 3 GRCh38: Ensembl release 89: ENSG00000096872 - Ensembl, May 2017
  2. 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000028576 - Ensembl, May 2017
  3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. "Entrez Gene: intraflagellar transport 74 homolog (Chlamydomonas)".
  6. 1 2 Bell SE, Mavila A, Salazar R, Bayless KJ, Kanagala S, Maxwell SA, Davis GE (August 2001). "Differential gene expression during capillary morphogenesis in 3D collagen matrices: regulated expression of genes involved in basement membrane matrix assembly, cell cycle progression, cellular differentiation and G-protein signaling". J. Cell Sci. 114 (Pt 15): 2755–73. doi:10.1242/jcs.114.15.2755. PMID   11683410.

Further reading