James T. Rosenbaum

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James T. Rosenbaum (born September 29, 1949) is an American physician-scientist who is Senior Vice President for Research at Corvus Pharmaceuticals [1] and Chief of Ophthalmology emeritus at the Legacy Devers Eye Institute, Portland, Oregon, where he held the Richard Chenoweth Chair. [2] Previously, he was Chief of Arthritis and Rheumatic Diseases at the Oregon Health & Science University where he held the Edward E Rosenbaum Professorship in Inflammation Research. [3] Rosenbaum was the only practicing rheumatologist/non-ophthalmologist in the world to serve as a chief of ophthalmology. He is recognized for his description of an animal model of uveitis (inflammation inside the eye) resulting from injection of bacterial endotoxin (Nature, 286:611, 1980) and for more than 600 scholarly publications, mostly related to the intersection between rheumatology and ophthalmology. [4] He is a co-author of the book, "The Clinical Neurology of Rheumatic Diseases". [5]

Contents

Education

Rosenbaum is a National Merit Scholar who graduated from Harvard College in 1971, magna cum laude. He graduated from Yale Medical School with honors in 1975. [4] He did an internship and residency in internal medicine at Stanford Medical Center from 1975 to 1978. He was a fellow of the Arthritis Foundation under the supervision of Hugh O. McDevitt at Stanford from 1978 to 1981. [6]

Family

Rosenbaum is part of a notable family that includes ten physicians including his father, Edward E Rosenbaum, author of "A Taste of My Own Medicine: When the Doctor Is the Patient". [7] His maternal grandmother was Rose Naftalin.

Honors

Rosenbaum is an elected member of the American Society of Clinical Investigation and the Association of American Physicians. He was given a lifetime achievement award from the American Academy of Ophthalmology. He was awarded the Friedenwald Award from the Association for Research in Vision and Ophthalmology in 2011, [6] the Gold Medal from the International Uveitis Study Group Eye Foundation in 2012, [8] the Cless Award from the University of Illinois, Chicago in 2012, [9] and the American College of Rheumatology Distinguished Clinician Scholar Award in 2013. [10] His first authored papers or essays have appeared in journals that include Science, [11] Nature, [12] the New England Journal of Medicine, [13] JAMA, [14] [15] Annals of Internal Medicine, [16] the Archives of Internal Medicine [17] and the online source for physicians, UpToDate.

Related Research Articles

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<span class="mw-page-title-main">Uveitis</span> Inflammation of the uvea of the eye

Uveitis is inflammation of the uvea, the pigmented layer of the eye between the inner retina and the outer fibrous layer composed of the sclera and cornea. The uvea consists of the middle layer of pigmented vascular structures of the eye and includes the iris, ciliary body, and choroid. Uveitis is described anatomically, by the part of the eye affected, as anterior, intermediate or posterior, or panuveitic if all parts are involved. Anterior uveitis (iridocyclitis) is the most common, with the incidence of uveitis overall affecting approximately 1:4500, most commonly those between the ages of 20-60. Symptoms include eye pain, eye redness, floaters and blurred vision, and ophthalmic examination may show dilated ciliary blood vessels and the presence of cells in the anterior chamber. Uveitis may arise spontaneously, have a genetic component, or be associated with an autoimmune disease or infection. While the eye is a relatively protected environment, its immune mechanisms may be overcome resulting in inflammation and tissue destruction associated with T-cell activation.

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<span class="mw-page-title-main">Axial spondyloarthritis</span> Medical condition

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References

  1. ↑ "Leadership". Corvus Pharmaceuticals. Retrieved 2023-05-14.
  2. ↑ "James T. Rosenbaum MD". Legacyhealth.org. Retrieved 2013-11-06.
  3. ↑ "James T. Rosenbaum, M.D. | Arthritis & Rheumatic Diseases (Adult) | OHSU". Ohsu.edu. Archived from the original on 2013-11-07. Retrieved 2013-11-06.
  4. 1 2 Nature Reviews Rheumatology (May 2012). "About the authors : Spondyloarthritis: The eyes have it: uveitis in patients with spondyloarthritis : Nature Reviews Rheumatology". Nature Reviews Rheumatology. Nature.com. 8 (5): 249–250. doi:10.1038/nrrheum.2012.43. PMC   3343203 . PMID   22469907.
  5. ↑ Lahita, Robert G. (1997). "Book Review Clinical Neurology of Rheumatic Diseases by Richard B. Rosenbaum, Stephen M. Campbell, and James T. Rosenbaum. 436 pp. Illustrated. Boston, Butterworth–Heinemann, 1996. $95. 0-7506-9613-3". New England Journal of Medicine. 336 (19): 1397. doi:10.1056/NEJM199705083361922.
  6. 1 2 Friederike Mackensen (2011-09-28). "Introducing James T. Rosenbaum, the 2011 Recipient of the Friedenwald Award". Iovs.org. Retrieved 2013-11-06.
  7. ↑ Steve Beaven; The Oregonian (June 2009). "Prominent Portland doctor and author dies". OregonLive.com. Retrieved 2013-11-06.
  8. ↑ 8th International Symposium on Uveitis (PDF), International Uveitis Study Group, 2012, p. 7, archived from the original (PDF) on 2014-05-12
  9. ↑ "Donor Events - University of Illinois College of Medicine a". Chicago.medicine.uic.edu. 2012-10-05. Retrieved 2013-11-06.
  10. ↑ "Awards of Distinction and Masters | American College of Rheumatology | ACR". Rheumatology.org. Retrieved 2013-11-06.
  11. ↑ Rosenbaum, JT (1997). "Lessons from litigation over silicone breast implants: A call for activism by scientists". Science. 276 (5318): 1524–5. doi:10.1126/science.276.5318.1524. PMID   9190690.
  12. ↑ Rosenbaum, JT; McDevitt, HO; Guss, RB; Egbert, PR (1980). "Endotoxin-induced uveitis in rats as a model for human disease". Nature. 286 (5773): 611–3. Bibcode:1980Natur.286..611R. doi:10.1038/286611a0. PMID   7402339. S2CID   4362456.
  13. ↑ Rosenbaum, James T. (2012). "Eyeing Macular Degeneration — A Few Inflammatory Remarks". New England Journal of Medicine. 367 (8): 768–70. doi:10.1056/NEJMcibr1204973. PMID   22913688.
  14. ↑ Rosenbaum, James T. (2009). "Howard". JAMA. 302 (9): 929–30. doi:10.1001/jama.2009.1170. PMID   19724031.
  15. ↑ Rosenbaum, James T. (2008). "In Defense of Phobias". JAMA. 299 (20): 2368. doi:10.1001/jama.299.20.2368. PMID   18505937.
  16. ↑ Rosenbaum, JT (1981). "Why HLA-B27: An analysis based on two animal models". Annals of Internal Medicine. 94 (2): 261–3. doi:10.7326/0003-4819-94-2-261. PMID   6937155.
  17. ↑ Rosenbaum, JT (1989). "Uveitis. An internist's view". Archives of Internal Medicine. 149 (5): 1173–6. doi:10.1001/archinte.149.5.1173. PMID   2719509.
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