AstraZeneca plc (AZ) is a British-Swedish multinational pharmaceutical and biotechnology company with its headquarters at the Cambridge Biomedical Campus in Cambridge,England. It has a portfolio of products for major diseases in areas including oncology,cardiovascular,gastrointestinal,infection,neuroscience,respiratory,and inflammation. It has been involved in developing the Oxford–AstraZeneca COVID-19 vaccine.
Frank Edward Young was an American physician who served as Commissioner of Food and Drugs from 1984 to 1989 and later as a deputy assistant secretary in the United States Department of Health and Human Services. In 2013 he joined Braeburn Pharmaceuticals as executive vice president,clinical and regulatory affairs. In 2018,he became the executive vice president of clinical and regulatory affairs at TissueTech Inc.
Andrew C. von Eschenbach was the Commissioner of the United States Food and Drug Administration from 2006 to 2009. He became acting Commissioner on September 26,2005,after the resignation of his predecessor Lester Crawford,and was confirmed as Commissioner by the Senate on December 7,2006. He was previously the 12th director of the National Cancer Institute.
Herbert Leonard Ley Jr. was an American physician and the 10th Commissioner and head of the U.S. Food and Drug Administration (FDA).
Tremelimumab,sold under the brand name Imjudo,is a fully human monoclonal antibody used for the treatment of hepatocellular carcinoma. Tremelimumab is designed to attach to and block CTLA-4,a protein that controls the activity of T cells,which are part of the immune system.
Sir Menelaos (Mene) Nicolas Pangalos is a British neuroscientist of Greek descent.
Stephen Michael Hahn is an American physician who served as the commissioner of food and drugs from 2019 to 2021. Before becoming commissioner,he was an oncologist serving as chief medical executive of the MD Anderson Cancer Center. In 2021,he became chief medical officer at Flagship Pioneering,the venture capital firm that launched Moderna.
Margaret Ann "Peggy" Hamburg is an American physician and public health administrator,who is serving as the chair of the board of the American Association for the Advancement of Science (AAAS) and co-chair of the InterAcademy Partnership (IAP). She served as the 21st Commissioner of the U.S. Food and Drug Administration from May 2009 to April 2015.
Sue Desmond-Hellmann is an American oncologist and biotechnology leader who served as the Chief Executive Officer of the Bill &Melinda Gates Foundation from 2014 to 2020. In March 2024 she was elected as a board member of OpenAI. She was previously Chancellor of the University of California,San Francisco (UCSF),the first woman to hold the position,and Arthur and Toni Rembe Rock Distinguished Professor,and before that president of product development at Genentech,where she played a role in the development of the first gene-targeted cancer drugs,Avastin and Herceptin.
The Reagan-Udall Foundation for the Food and Drug Administration is a private nonprofit (501c3) organization,created to support the mission of the U.S. Food and Drug Administration (FDA) to help equip FDA staff with the highest caliber,regulatory science and technology in order to enhance the safety and effectiveness of FDA regulated products. Although it was mandated by Congress in the Food and Drug Administration Amendments Act of 2007 to help support and promote FDA's regulatory science priorities,it is independent of the agency,with its own Board of Directors,staff and research agenda. The Reagan-Udall Foundation creates public–private partnerships to advance research in regulatory science,enhance medical decision making,and promote innovation. It also advances regulatory science through fellowships and other training programs,both for private scientists and for FDA staff.
Brodalumab,sold under the brand name Siliq in the US and Kyntheum in the EU,is a human monoclonal antibody designed for the treatment of inflammatory diseases.
Moxetumomab pasudotox,sold under the brand name Lumoxiti,is an anti-CD22 immunotoxin medication for the treatment of adults with relapsed or refractory hairy cell leukemia (HCL) who have received at least two prior systemic therapies,including treatment with a purine nucleoside analog. Moxetumomab pasudotox is a CD22-directed cytotoxin and is the first of this type of treatment for adults with HCL. The drug consists of the binding fragment (Fv) of an anti-CD22 antibody fused to a toxin called PE38. This toxin is a 38 kDa fragment of Pseudomonas exotoxin A.
Brett P. Giroir is an American pediatrician. He was formerly the U.S. assistant secretary for health,a four-star admiral in the U.S. Public Health Service Commissioned Corps and an acting Food and Drug Administration commissioner.
Sherilyn S. McCoy is an American scientist and business executive. She is the former CEO of Avon Products and former vice chairman and member of the office of the chairman of Johnson &Johnson,where she was responsible for the pharmaceutical and consumer business divisions of the company. She was appointed as the vice chairman in January 2011,after which she was named by Fortune Magazine,as the 10th woman on their list of "50 Most Powerful Women in Business",a list on which she has been included since 2008. In February 2012,she resigned her employment with Johnson &Johnson after 30 years and was subsequently named as the CEO of Avon Products. In August 2012,she was recognized as the 39th most powerful woman in the world by Forbes Magazine.
Luciana Borio is a Brazilian-American infectious disease physician and public health administrator. She is a vice president at In-Q-Tel. She previously served as director for Medical and Biodefense Preparedness at the National Security Council,acting chief scientist of the U.S. Food and Drug Administration (FDA),assistant commissioner for counterterrorism policy of the FDA,and director of FDA's Office of Counterterrorism and Emerging Threats. She is known for her work advancing clinical trials,the development of medical countermeasures for health emergencies,and the public health responses to Ebola and Zika outbreaks.
Robert McKinnon Califf is an American cardiologist who currently serves as the 25th Commissioner of the Food and Drug Administration.
The Institute for Clinical and Economic Review (ICER) is a Boston-based independent nonprofit organization that seeks to place a value on medical care by providing comprehensive clinical and cost-effectiveness analyses of treatments,tests,and procedures.
Janet Woodcock is an American physician serving as Principal Deputy Commissioner of Food and Drugs,having previously served as Acting Commissioner of the U.S. Food and Drug Administration (FDA). She joined the FDA in 1986,and has held a number of senior leadership positions there,including terms as the Director of Center for Drug Evaluation and Research (CDER) from 1994 to 2004 and 2007 to 2021.
Stella Kyriakides is a Cypriot psychologist and politician of the conservative Democratic Rally party who has been serving as European Commissioner for Health and Food Safety since 2019. She was the first Cypriot national and third woman to serve as President of the Parliamentary Assembly of the Council of Europe.
Tixagevimab/cilgavimab,sold under the brand name Evusheld,is a combination of two human monoclonal antibodies,tixagevimab (AZD8895) and cilgavimab (AZD1061) targeted against the surface spike protein of SARS-CoV-2 used to prevent COVID-19. It is being developed by British-Swedish multinational pharmaceutical and biotechnology company AstraZeneca. It is co-packaged and given as two separate consecutive intramuscular injections.
