Janet L. Mitchell (March 15, 1950 - September 1, 2019) was an American physician known for her advances in perinatal HIV/AIDS treatment. During the early days of the AIDS epidemic in the U.S. Mitchell developed protocols for health treatment of pregnant women who were HIV positive or at risk for developing AIDS. She advocated against mandatory testing and testifying before Congress, she advocated in favor of an inclusive approach to health care and social services. One of her innovations derived from a study that saw a 70% decrease in HIV transmission to babies when AZT was administered to their mothers during the pregnancy.
Janet Louise Mitchell was born in Lexington, Kentucky to Richard, a horse jockey, trainer, butler and driver and Minnie Mitchell (nee Smith). The family lived in a segregated government housing project with the children attending segregated schools for most of their childhood. Despite the limited opportunities for African-Americans and the fact that Richard, who was born an indentured servant, only had a fifth-grade education, he and his wife stressed the importance of academic achievement in the household. Subsequently, all five of their children went on to attend and graduate from university.
Mitchell attended Mount Holyoke College for her undergraduate education, graduating with a bachelor's degree in 1972. She then attended Howard University College of Medicine. While in medical school she struggled academically, almost dropping out after her first year, later discovering she had dyslexia. Mitchell sought help, continued her studies and graduated in 1976. She returned to school later in her career and earned a master's of public health at Harvard University, graduating in 1987., [1] During this time, she was appointed in 1983 to serve on the newly formed New York State AIDS Advisory Council. She was involved in developing policy for controlling infection via procedures written for healthcare workers. [2] Mitchell often credited her upbringing as being instrumental in her choice of career and her focus on marginalized communities, and in particular, women. In a 2003 interview with Changing the Face of Medicine, she stated, "I grew up in a government project with two wonderful parents. Working at Harlem [Hospital] and doing almost all of my rotations in medical school at [Washington] D.C. General Hospital. I said 'there but by the grace of God go I.' I have ever since devoted myself to the under-served and the most disenfranchised." [3]
In 1988, Mitchell became the department head of obstetrics and gynecology at Harlem Hospital Center, a position she held until 1996. During this time, she was responsible for its perinatal drug addiction program, the largest in New York City. Mitchell cared for uninsured and HIV-positive patients. [1] In 1994, she was commissioned to write a paper for the Institute of Medicine evaluating the disparity of inclusion of minority women in AIDS research. While she noted that all women were routinely omitted from clinical trials, she successfully argued that when women were included in studies, women of color were routinely underrepresented. Her lobbying was successful in a policy shift by the National Institutes of Health to ensure the inclusion of black women in ongoing drug trials for HIV/AIDS in pregnant women. [2] Her research has been primarily in this area; she studied perinatal AIDS education and prevention with the Centers for Disease Control from 1988 to 1992, and pregnancy in African-American women. [1] She served as an assistant Professor of Obstetrics and Gynecology at Columbia University and chair of the Consensus Panel at the Center of Substance Abuse within the supervision of the Department of Health and Human Services and the Public Health Service. The panel developed a Treatment Improvement Protocol in 1993 for pregnant women who were also substance abusers. [2]
In the early days of the AIDS epidemic many programs were tried and Mitchell was often consulted to review solutions. She was called as an expert witness to testify before Congress on children and HIV infection in 1989 [4] and again in 1990 to discuss underrepresentation of minorities and drug abusers. She and others recommended coordinated services between health care and social and psychological help as a means of stemming the epidemic. [5] As a means of confirming this recommendation, Mitchell conducted a study from 1989 to 1992 which evaluated three separate groups of women and the way that health services and education about HIV transmission was delivered to them. Her findings concluded that risk is most successfully reduced if education is incorporated into a routine clinical program meeting the basic health needs of patients. [6]
One of her innovations was the result of a study conducted in 1986 which administered AZT to pregnant women to reduce transmission rate to their babies. The study showed almost 70% reduction in transmission rates for women when started between 13 and 34 weeks of gestation. As a result of her study, use of AZT became the standard of care for at risk and HIV positive mothers. [2] Mitchell kept statistics and performed maternal death reviews for New York City during her tenure at the hospital. During the decade of her employment, maternal deaths in the United States showed that for every 5,102 births, one black mother died, compared to one white mother in 18,868. [7] Mitchell was strongly against policies of mandatory AIDS testing, believing that it was an attempt to identify a problem, rather than take action on the problem. [8]
Mitchell has written more than fifty articles and book chapters related to her areas of specialization. She has received two major grant awards from the Centers for Disease Control, one for a perinatal HIV and Aids education and reduction demonstration project from 1988 to 1992 and the other to study pregnancy and pregnancy outcomes of African-American women in the United States from 1993 to 1997. In 1993 she chaired the consensus panel to develop the Pregnant, Substance-abusing Women, Treatment Improvement Protocol for the Substance Abuse and Mental Health Services Administration under the United States Department of Health and Human Services.
Mitchell has worked as director of outreach, chief of obstetrics, and residency director in the Department of Obstetrics and Gynecology and Reproductive Medicine at Lincoln Medical and Mental Health Center in The Bronx, New York.
Mitchell married Arthur Glass Jr. a vice president at the Jackie Robinson Foundation of New York City in 1991, [9] but they later divorced. Mitchell developed early Alzheimer's disease and was placed in long-term care. In 2007, Mitchell was a featured subject in a Nightline program which explored the vulnerabilities of people with early onset dementia. [10]
Dr. Mitchell died in Fort Collins, Colorado on September 1, 2019 from complications of Alzheimer's disease. She was 69 years old.
Zidovudine (ZDV), also known as azidothymidine (AZT), was the first antiretroviral medication used to prevent and treat HIV/AIDS. It is generally recommended for use in combination with other antiretrovirals. It may be used to prevent mother-to-child spread during birth or after a needlestick injury or other potential exposure. It is sold both by itself and together as lamivudine/zidovudine and abacavir/lamivudine/zidovudine. It can be used by mouth or by slow injection into a vein.
Maternal death or maternal mortality is defined in slightly different ways by several different health organizations. The World Health Organization (WHO) defines maternal death as the death of a pregnant mother due to complications related to pregnancy, underlying conditions worsened by the pregnancy or management of these conditions. This can occur either while she is pregnant or within six weeks of resolution of the pregnancy. The CDC definition of pregnancy-related deaths extends the period of consideration to include one year from the resolution of the pregnancy. Pregnancy associated death, as defined by the American College of Obstetricians and Gynecologists (ACOG), are all deaths occurring within one year of a pregnancy resolution. Identification of pregnancy associated deaths is important for deciding whether or not the pregnancy was a direct or indirect contributing cause of the death.
The Elizabeth Glaser Pediatric AIDS Foundation (EGPAF) is a nonprofit organization dedicated to preventing pediatric HIV infection and eliminating pediatric AIDS through research, advocacy, and prevention and treatment programs. Founded in 1988, the organization works in 12 countries around the world.
Christine Joy Maggiore was an HIV-positive activist and promoter of HIV/AIDS denialism. She was the founder of Alive & Well AIDS Alternatives, an organization which disputes the link between HIV and AIDS and urges HIV-positive pregnant women to avoid anti-HIV medication. Maggiore authored and self-published the book What If Everything You Thought You Knew about AIDS Was Wrong?
AIDS service organizations are community-based organizations that provide support for people affected by HIV/AIDS. This article focuses on HIV/AIDS service organizations in the United States only. However, it is important to note that similar organizations in other countries, such as Canada, also played significant roles during the HIV/AIDS crisis and share many common experiences and challenges.
Maternal health is the health of women during pregnancy, childbirth, and the postpartum period. In most cases, maternal health encompasses the health care dimensions of family planning, preconception, prenatal, and postnatal care in order to ensure a positive and fulfilling experience. In other cases, maternal health can reduce maternal morbidity and mortality. Maternal health revolves around the health and wellness of pregnant women, particularly when they are pregnant, at the time they give birth, and during child-raising. WHO has indicated that even though motherhood has been considered as a fulfilling natural experience that is emotional to the mother, a high percentage of women develop health problems and sometimes even die. Because of this, there is a need to invest in the health of women. The investment can be achieved in different ways, among the main ones being subsidizing the healthcare cost, education on maternal health, encouraging effective family planning, and ensuring progressive check up on the health of women with children. Maternal morbidity and mortality particularly affects women of color and women living in low and lower-middle income countries.
Maternal–fetal medicine (MFM), also known as perinatology, is a branch of medicine that focuses on managing health concerns of the mother and fetus prior to, during, and shortly after pregnancy.
Mirudhubashini Govindarajan is an Indian-born healthcare consultant, focussing on women's healthcare and infertility management in Coimbatore, Tamil Nadu, India.
The following outline is provided as an overview of and topical guide to obstetrics:
Mark V. Sauer is an American physician who specializes in reproductive medicine. He is a clinician, researcher and medical educator best known for his work in the development of egg and embryo donation, fertility care of HIV-seropositive patients, and reproductive bioethics. He currently is Professor and Chairman of Obstetrics, Gynecology and Reproductive Sciences at Rutgers Robert Wood Johnson Medical School in New Brunswick, New Jersey. He also serves as the Senior Associate Dean for Women's Health there. Sauer was the Chief of the Division of Reproductive Endocrinology at Columbia University Medical Center in New York City for twenty-one years, where he was also the program and laboratory director of the Center for Women's Reproductive Care, and a tenured professor and vice-chairman in the Department of Obstetrics and Gynecology at the College of Physicians and Surgeons, Columbia University. While at Columbia University he also served on the Medical Ethics Committee of New York Presbyterian-Columbia University Medical Center.
A pre-existing disease in pregnancy is a disease that is not directly caused by the pregnancy, in contrast to various complications of pregnancy, but which may become worse or be a potential risk to the pregnancy. A major component of this risk can result from necessary use of drugs in pregnancy to manage the disease.
Obstetric medicine, similar to maternal medicine, is a sub-specialty of general internal medicine and obstetrics that specializes in process of prevention, diagnosing, and treating medical disorders in with pregnant humans. It is closely related to the specialty of maternal-fetal medicine, although obstetric medicine does not directly care for the fetus. The practice of obstetric medicine, or previously known as "obstetric intervention," primarily consisted of the extraction of the baby during instances of duress, such as obstructed labor or if the baby was positioned in breech.
Jean R. Anderson is an American obstetrician and gynaecologist, most well known for being the founder and first director of Johns Hopkins HIV Women's Health Program (1991).
HIV in pregnancy is the presence of an HIV/AIDS infection in a woman while she is pregnant. There is a risk of HIV transmission from mother to child in three primary situations: pregnancy, childbirth, and while breastfeeding. This topic is important because the risk of viral transmission can be significantly reduced with appropriate medical intervention, and without treatment HIV/AIDS can cause significant illness and death in both the mother and child. This is exemplified by data from The Centers for Disease Control (CDC): In the United States and Puerto Rico between the years of 2014–2017, where prenatal care is generally accessible, there were 10,257 infants in the United States and Puerto Rico who were exposed to a maternal HIV infection in utero who did not become infected and 244 exposed infants who did become infected.
In the United States, prisons are obligated to provide health care to prisoners. Such health care is sometimes called correctional medicine. In women's prisons, correctional medicine includes attention to reproductive health.
Maternal healthcare in Texas refers to the provision of family planning services, abortion options, pregnancy-related services, and physical and mental well-being care for women during the prenatal and postpartum periods. The provision of maternal health services in each state can prevent and reduce the incidence of maternal morbidity and mortality and fetal death.
Amos Grunebaum is an American obstetrician and gynecologist. He serves as Professor of Obstetrics and Gynecology at the Zucker School of Medicine, as Professor Emeritus at the medical school Weill Cornell Medicine, and as a specialist in maternal-fetal medicine and high-risk pregnancies. He is also the founder of Babymed.com, which is a website for pregnant women and those trying to conceive, the site is up since 2000.
Many women have been infected with the HIV/AIDS virus. The majority of HIV/AIDS cases in women are directly influenced by high-risk sexual activities, injectional drug use, the spread of medical misinformation, and the lack of adequate reproductive health resources in the United States. Women of color, LGBT women, homeless women, women in the sex trade, and women intravenous drug users are at a high-risk for contracting the HIV/AIDS virus. In an article published by the Annual Review of Sociology, Celeste Watkins Hayes, an American sociologist, scholar, and professor wrote, "Women are more likely to be forced into survival-focused behaviors such as transactional sex for money, housing, protection, employment, and other basic needs; power-imbalanced relationships with older men; and other partnerings in which they cannot dictate the terms of condom use, monogamy, or HIV." The largest motivator to become part of the sex trade was addiction, the second largest being basic needs, and the third was to support their children/family.
Hendrée E. Jones is a researcher on women's substance abuse disorders and its impact on children. She is a professor in the Department of Obstetrics and Gynecology at the University of North Carolina School of Medicine, and adjunct professor in the University of North Carolina College of Arts & Sciences Department of Psychology and Neuroscience. Jones is the executive director of the UNC Horizons Program, which is a comprehensive drug treatment program for mothers and their drug-exposed children. She is a consultant for the Substance Abuse and Mental Health Services Administration, the United Nations, and the World Health Organization.
Jeannette R. Ickovics is an American health and social psychologist. She is the inaugural Samuel and Liselotte Herman Professor of Social and Behavioral Sciences at the Yale School of Public Health and Professor of Psychology at the Graduate School of Arts and Sciences at Yale University.