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Jennifer Anne Doudna is an American chemist who has done pioneering work in CRISPR gene editing, and made other fundamental contributions in biochemistry and genetics. Doudna was one of the first women to share a Nobel in the sciences. She received the 2020 Nobel Prize in Chemistry, with Emmanuelle Charpentier, "for the development of a method for genome editing." She is the Li Ka Shing Chancellor's Chair Professor in the department of chemistry and the department of molecular and cell biology at the University of California, Berkeley. She has been an investigator with the Howard Hughes Medical Institute since 1997.
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Emmanuelle Marie Charpentier is a French professor and researcher in microbiology, genetics, and biochemistry. As of 2015, she has been a director at the Max Planck Institute for Infection Biology in Berlin. In 2018, she founded an independent research institute, the Max Planck Unit for the Science of Pathogens. In 2020, Charpentier and American biochemist Jennifer Doudna of the University of California, Berkeley, were awarded the Nobel Prize in Chemistry "for the development of a method for genome editing". This was the first science Nobel Prize ever won by two women only.
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Anna Perdrix Rosell is a Spanish scientist who completed her PhD in cancer cell signalling at the Francis Crick Institute in London. She co-founded a biotech start-up, which helped her get onto the Forbes 30 under 30 list in 2018.
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CRISPR Therapeutics AG is a Swiss–American biotechnology company headquartered in Zug, Switzerland. It was one of the first companies formed to utilize the CRISPR gene editing platform to develop medicines for the treatment of various rare and common diseases. The company has approximately 500 employees and has offices in Zug, Switzerland, Boston, Massachusetts, San Francisco, California and London, United Kingdom. Its manufacturing facility in Framingham, Massachusetts won the Facilities of the Year Award (FOYA) award in 2022. The company’s lead program, exagamglogene autotemcel, or exa-cel, was granted regulatory approval by the US Food and Drug Administration (FDA) in December 2023.
Flagship Pioneering is an American life sciences venture capital company based in Cambridge, Massachusetts that invests in biotechnology, life sciences, health and sustainability companies. Portfolio companies include Moderna, Indigo Agriculture, Inari Agriculture and Novomer. The firm both funds and incubates companies.
Mammoth Biosciences is a biotechnology company based in Brisbane, California developing diagnostic tests using CRISPR-Cas12a and CRISPR-based therapies using its proprietary ultra-small CRISPR systems. Several CRISPR-Cas systems identified through the company's metagenomics-based protein discovery platform, including members of the Casφ and Cas14 families of CRISPR-associated enzymes, have demonstrated potential for therapeutic genome editing in in vivo settings.
Sherlock Biosciences is a biotechnology company based in Cambridge, Massachusetts developing diagnostic tests using CRISPR-Cas13. The company was founded in 2019 by Feng Zhang, Jim Collins, Omar Abudayyeh, and Jonathan Gootenberg of the Broad Institute.
The Innovative Genomics Institute (IGI) is a nonprofit scientific research institute founded by Nobel laureate and CRISPR gene editing pioneer Jennifer Doudna and biophysicist Jonathan Weissman. The institute is based at the University of California, Berkeley, and also has member researchers at the University of California, San Francisco, UC Davis, UCLA, Lawrence Berkeley National Laboratory, Lawrence Livermore National Laboratory, Gladstone Institutes, and other collaborating research institutions. The IGI focuses on developing real-world applications of genome editing to address problems in human health, agriculture and climate change.
References
- ↑ "30 Under 30 Spotlight: Unsung Heroes in Healthcare Janice Chen | Forbes Healthcare Summit 2019". Forbes . December 16, 2019. Retrieved May 12, 2020.
- ↑ Dutton, Gail (April 24, 2020). "Mammoth's CRISPR Assay for Asymptomatic COVID-19 Carriers Gains Peer-Reviewed Validation". BioSpace. Retrieved May 12, 2020.
- 1 2 "Janice Chen". TEDx CERN. Retrieved May 12, 2020.
- ↑ "Mammoth Biosciences Co-Founders Trevor Martin, Janice Chen and Lucas Harrington Named to 2018 Forbes' 30 Under 30". WebWire. November 15, 2018. Retrieved May 25, 2020.
- ↑ Ramsey Pflanzer, Lydia; Leonard, Kimberly; Hernbroth, Megan; Dunn, Andrew; Dodge, Blake (12 October 2020). "Meet the 30 young leaders who are forging a new future for the $3.6 trillion healthcare industry". Business Insider . Retrieved 20 February 2022.
- ↑ Gelman, Max (10 December 2020). "Special report: Twenty extraordinary women blazing trails in biopharma R&D — Covid-19 and beyond". Endpoints News. Retrieved 20 February 2022.
- ↑ Regalado, Antonio (30 June 2021). "35 Innovators Under 35". MIT Technology Review . Retrieved 20 February 2021.
- 1 2 Fannin, Rebecca. "The 30-year-old female founder at the forefront of a billion-dollar bet on CRISPR gene editing". CNBC . Retrieved 2023-01-30.
- ↑ Pham, Jason (February 4, 2022). "Nathan Chen Is the 'Baby' of 5 Kids—Meet the Olympian's Parents & Siblings". Yahoo Sports!.