Jill Bargonetti

Last updated
Jill Bargonetti
Jill Bargonetti Head Shot.jpg
Born
New York, NY, U.S.
CitizenshipAmerican
Alma mater New York University
Known for p53
Awards Presidential Early Career Award for Scientists and Engineers (1997)
Scientific career
Fields Cancer Research
Institutions Hunter College

Jill Bargonetti (born October 10, 1962) is an American professor at the City University of New York with dual appointments at Hunter College and The Graduate Center. Her research is focused on tumor suppressor protein p53 and its role as an oncogene when it is mutated in breast cancer.

Contents

Early life and education

Born on October 10, 1962, in New York Hospital, Jill Bargonetti is the daughter of Adah Askew and Arthur Bargonetti. Jill was born to a Black mother and an Italian American father. [1] She grew up in a strategically multi-ethnic and culturally diverse Mitchel-Lama housing development on Manhattan’s Upper West Side. [1] Bargonetti attended three of New York City’s special public schools: Hunter College Elementary School, Hunter College High School and The Bronx High School of Science. She went on to attend the State University of New York at Purchase where she majored in biology and dance and earned a B.A. in Biology. She then received her Masters from New York University in 1987 followed by her Ph.D. from NYU in 1990. [2] She did a postdoctoral fellowship at Columbia University from 1990 until 1994, where she worked alongside Dr. Carol Prives. There, she characterized important functions of p53 needed for tumor suppression and that they were lost when p53 is mutated in cancer. [3]

Career

Bargonetti’s first professional positions in the 1980s were as a dancer with a Harlem-based dance company called Dianne McIntyre’s Sounds in Motion [4] and as a research technician at Rockefeller University. [2] Following her doctoral and postdoctoral training, in 1994 Bargonetti became an assistant professor at The City University of New York with appointments at Hunter College and The Graduate Center. She chose the City University of New York in part to be a role model for other people from groups underrepresented in the sciences. In 1997, she was awarded the Presidential Early Career Award for Scientists and Engineers from President Bill Clinton for “scholarly work in cancer related studies of cell growth and gene expression and involvement of undergraduate, graduate and especially minority students in the discovery process.” [5]   She became a full professor at Hunter College in 2007, the Chair of the Molecular, Cellular, and Developmental Biology (MCD) PhD subprogram of the CUNY Graduate Center in 2009, and the leader of the New York Research and Mentoring for Postbaccalaureates (NY-RaMP) program at Hunter College in 2023. [6]

Bargonetti has served on numerous National Committee’s to evaluate science and policy. Some of her appointments include a 2012-2018 Membership in The National Institutes of Health (NIH) Tumor Cell Biology Study Section Review Committee and a working as a member of The National Cancer Policy Board from 2002 to 2005. [7] [6] [8]

Bargonetti was featured on a PBS series called "American Graduate Day" in 2015. [9] Additionally, she spoke at a TedX "Borders and Belonging" event at City University of New York (CUNY) in 2016. [10] She was noted as a New York University Graduate School of Arts and Sciences: Distinguished Alumna [11]   and a SUNY Purchase Presidential Distinguished Alumna. In 2017, Jill Bargonetti was inducted into the Bronx Science High School Hall of Fame.

Honors and awards

Related Research Articles

<span class="mw-page-title-main">City University of New York</span> Public university system in New York City

The City University of New York is the public university system of New York City. It is the largest urban university system in the United States, comprising 25 campuses: eleven senior colleges, seven community colleges, and seven professional institutions. In 1960, John R. Everett became the first chancellor of the Municipal College System of New York City, later known as the City University of New York (CUNY). CUNY, established by New York state legislation in 1961 and signed into law by Governor Nelson Rockefeller, was an amalgamation of existing institutions and a new graduate school.

<span class="mw-page-title-main">Hunter College</span> Constituent college of the City University of New York

Hunter College is a public university in New York City. It is one of the constituent colleges of the City University of New York and offers studies in more than one hundred undergraduate and postgraduate fields across five schools. It also administers Hunter College High School and Hunter College Elementary School.

The Graduate School and University Center of the City University of New York is a public research institution and postgraduate university in New York City. Formed in 1961 as Division of Graduate Studies at City University of New York, it was renamed to Graduate School and University Center in 1969. Serving as the principal doctorate-granting institution of the City University of New York (CUNY) system, CUNY Graduate Center is classified among "R1: Doctoral Universities – Very High Research Activity".

<span class="mw-page-title-main">Lehman College</span> Public college in the Bronx, New York

Lehman College is a public college in New York City. Founded in 1931 as the Bronx campus of Hunter College, it became an independent college in 1967. The college is named after Herbert H. Lehman, a former New York governor, United States senator, and philanthropist. It is a senior college of the City University of New York (CUNY) and offers more than 90 undergraduate and graduate degree programs and specializations.

<span class="mw-page-title-main">Hostos Community College</span> Community college in the Bronx, New York, U.S.

Eugenio María de Hostos Community College of The City University of New York is a public community college in the South Bronx, New York City. It is part of the City University of New York (CUNY) system and was created by an act of the Board of Higher Education in 1968 in response to demands from the Hispanic/Puerto Rican community, which was urging for the establishment of a college to serve the people of the South Bronx. In 1970, the college admitted its first class of 623 students at the site of a former tire factory. Several years later, the college moved to a larger site nearby at 149th Street and Grand Concourse. The college also operates a location at the prow building of the Bronx Terminal Market.

<span class="mw-page-title-main">Education in New York City</span>

Education in New York City is provided by a vast number of public and private institutions. New York City has the largest educational system of any city in the world. The city's educational infrastructure spans primary education, secondary education, higher education, and research. New York City is home to some of the most important libraries, universities, and research centers in the world. In 2006, New York had the most post-graduate life sciences degrees awarded annually in the United States, 40,000 licensed physicians, and 127 Nobel laureates with roots in local institutions. The city receives the second-highest amount of annual funding from the National Institutes of Health among all U.S. cities. It also struggles with disparity in its public school system, with some of the best-performing public schools in the United States as well as some of the worst-performing. Under Mayor Michael Bloomberg, the city embarked on a major school reform effort.

<span class="mw-page-title-main">Mina Rees</span> American mathematician (1902–1997)

Mina Spiegel Rees was an American mathematician. She is known for her assistance to the US Government during WWII, as well as making several breakthroughs for women in science. Her most notable accomplishments include becoming the first female President of the American Association for the Advancement of Science (1971) and head of the mathematics department of the Office of Naval Research of the US. Rees was a pioneer in the history of computing and helped establish funding streams and institutional infrastructure for research. She also helped other women succeed in mathematics with her involvement in the Association for Women in Mathematics as well as her life-long career as a professor at Hunter College.

Sir David Philip Lane is a British immunologist, molecular biologist and cancer researcher. He is currently working in the Department of Microbiology, Tumor and Cell Biology at the Karolinska Institute and is Chairman of Chugai Pharmabody. He is best known for the discovery of p53, one of the most important tumour suppressor genes.

<span class="mw-page-title-main">Jennifer Raab</span>

Jennifer J. Raab is the President and Chief Executive Officer of the New York Stem Cell Foundation, one of the world’s leading nonprofit stem cell organizations with a mission to accelerate cures for the major diseases of our time through stem cell research. Prior to her appointment in January 2024, she served as the 13th president of Hunter College of the City University of New York, where she transformed the largest college in the City University of New York system into its ‘crown jewel’ and a model for public higher education nationwide. Raab was the longest serving President in the CUNY system, holding this position between June 2001 and June 2023. She was responsible for overseeing the functions of the college's more than one hundred undergraduate and postgraduate fields across five schools as well its affiliates such as the Hunter College High School, Hunter College Elementary School and Manhattan/Hunter Science High School.

<span class="mw-page-title-main">William E. Macaulay Honors College</span> College at the City University of New York

William E. Macaulay Honors College, commonly referred to as Macaulay Honors College or Macaulay, is the honors college of the City University of New York (CUNY) system in New York City. It was founded in 2001 as CUNY Honors College.

The Center for Study of Gene Structure and Function is a consortium of fifty-three researchers. It is based at Hunter College in Manhattan. It focuses on cross-disciplinary and translational research by promoting dialogue and cooperation among scientists working in diverse biomedical research fields. It is funded by the Research Centers in Minority Institutions (RCMI) program of the National Center for Research Resources(NCRR) of the National Institute of Health (NIH) Since its establishment in 1985, the NIH has awarded the Gene Center over $38 million in federal grants.

Arnold Jay Levine, is an American molecular biologist. He was awarded the 1998 Louisa Gross Horwitz Prize for Biology or Biochemistry and was the first recipient of the Albany Medical Center Prize in Medicine and Biomedical Research in 2001 for his discovery of the tumor suppressor protein p53.

<span class="mw-page-title-main">Jewel Plummer Cobb</span> American biologist

Jewel Plummer Cobb was an American biologist, cancer researcher, professor, dean, and academic administrator. She contributed to the field of cancer research by studying the cure for melanoma. Cobb was an advocate for increasing the representation of women and students of color in universities, and she created programs to support students interested in pursuing graduate school.

<span class="mw-page-title-main">Carlos Cordon-Cardo</span> Spanish-born American physician and scientist

Carlos Cordon-Cardo is a Spanish-born American physician and scientist known for his research in experimental pathology and molecular oncology. He holds the "Irene Heinz Given and John LaPorte Given" Chair in Pathology at Mount Sinai School of Medicine.

Luis F. Parada is a Colombian developmental biologist and neuroscientist who currently serves as Director of the Brain Tumor Center, Albert C. Foster Chair and American Cancer Society Research Professor at Memorial Sloan Kettering Cancer Center in New York City, New York.

<span class="mw-page-title-main">Sanjeev Das</span> Indian cancer biologist and a scientist

Sanjeev Das is an Indian cancer biologist and a scientist at National Institute of Immunology, New Delhi, India. He is well regarded for his studies on tumor suppressor proteins. He is a recipient of the National Bioscience Award for Career Development of the Department of Biotechnology. The Council of Scientific and Industrial Research, the apex agency of the Government of India for scientific research, awarded him the Shanti Swarup Bhatnagar Prize for Science and Technology, one of the highest Indian science awards, for his contributions to biological sciences in 2017.

<span class="mw-page-title-main">Mandë Holford</span> American chemist

Mandë Holford is an associate professor in chemistry at Hunter College with scientific appointments at the American Museum of Natural History and Weill Cornell Medical College. Her interdisciplinary research covering 'mollusks to medicine' spans chemistry and biology and aims to discover, characterize, and deliver novel peptides from venomous marine snails as tools for manipulating cellular physiology in pain and cancer.

Guillermina 'Gigi' Lozano is an American geneticist. She is a Professor and Hubert L. Olive Stringer Distinguished Chair in Oncology in Honor of Sue Gribble Stringer at the University of Texas MD Anderson Cancer Center, Houston, Texas. Lozano is recognised for her studies of the p53 tumour suppressor pathway, characterising the protein as a regulator of gene expression and that is disturbed in many cancers. She was the first to recognize that the p53 gene encoded a transcriptional activator of other genes Her lab has made significant contributions by developing and analyzing mouse models to study the activities of mutant p53, revealing how these mutations drive tumor development and progression. She also found out how the Mdm2 and Mdm4 proteins work in the body, especially in stopping cancer and controlling p53. This research suggested that blocking Mdm2/4 could be a new way to treat cancer.

References

  1. 1 2 ^ Hunter, Karen (15 November 1997). "Her In-Gene-Uity Pays Work Reveals Cancer Cure".
  2. 1 2 Bargonetti-Chavarria, Jill (2002-03-22). "MSN Shero--Jill Bargonetti-Chavarria, Ph.D." Science | AAAS. Retrieved 2020-06-22.
  3. ↑ Armstrong, Sue (3 May 2016). P53 : the gene that cracked the cancer code. London. ISBN   978-1-4729-1052-3. OCLC   929031485.{{cite book}}: CS1 maint: location missing publisher (link)
  4. ↑ Dunning, Jennifer (1984-06-20). "Dance: Dianne Mcintyre's Sounds in Motion". The New York Times. ISSN   0362-4331 . Retrieved 2020-06-22.
  5. ↑ "The Presidential Early Career Award for Scientists and Engineers: Recipient Details | NSF - National Science Foundation". www.nsf.gov. Retrieved 2020-06-22.
  6. 1 2 "Jill Bargonetti". www.gc.cuny.edu. Retrieved 2020-06-22.
  7. ↑ Herdman, Roger; Lichtenfeld, Leonard (2004). "National Cancer Policy Board". Institute of Medicine and National Research Council, National Cancer Policy Board. National Academies Press (US).
  8. ↑ Arenson, Karen W. (2001-05-29). "Scientist at Work: Jill Bargonetti – A Biologist's Choice Gives Priority to Students". The New York Times. ISSN   0362-4331 . Retrieved 2020-06-22.
  9. ↑ "Professor Jill Bargonetti (PBS)". YouTube. 8 October 2015.
  10. ↑ "Choreographing Genomics | Jill Bargonetti + Choreographing Genomics Team | TEDxCUNY". YouTube. 25 January 2016.
  11. ↑ "GSAS Alumni Achievement Award Recipients" (PDF). NYU Graduate School of Arts and Sciences. Retrieved 2020-06-22.
  12. ↑ "JILL BARGONETTI". The Graduate Center City University of New York.
  13. ↑ Lang, Sinaia (30 May 2018). "Recognizing a Dancer-Turned-Researcher".
This page is based on this Wikipedia article
Text is available under the CC BY-SA 4.0 license; additional terms may apply.
Images, videos and audio are available under their respective licenses.