John Crump

Last updated
John A. Crump
John A Crump.jpg
Crump in 2019
Alma mater University of Otago
London School of Hygiene and Tropical Medicine
Awards James H. Steele Veterinary Public Health Award (US Centers for Disease Control and Prevention, 2005)

Bailey K. Ashford Medal (American Society of Tropical Medicine and Hygiene, 2012)

Contents

Chalmers Medal (Royal Society of Tropical Medicine and Hygiene, 2022)

Scientific career
FieldsInfectious diseases
Medical microbiology
Epidemiology
Tropical medicine
Zoonoses
Institutions University of Otago
US Centers for Disease Control and Prevention
Duke University
Thesis HIV prevention, treatment, and care in sub-Saharan Africa
Website https://www.otago.ac.nz/healthsciences/expertise/profile?id=1104

John Andrew Crump is a New Zealand-born infectious diseases physician, medical microbiologist, and epidemiologist. He is Professor of Medicine, Pathology, and Global Health at the University of Otago [1] and an adjunct professor of medicine, Pathology, and Global Health at Duke University. [2] He serves as Director of the Otago Global Health Institute, [3] one of the university's research centres. [4] His primary research interest is fever in the tropics, focusing on invasive bacterial diseases and bacterial and viral zoonoses. [1]

Early life and education

Crump was born in Oamaru and raised on a farm at Okaramio, attending Havelock School [5] and Marlborough Boys’ College. [6] He graduated MB ChB in 1993 and completed his MD doctoral thesis in 2013 on clinical and laboratory aspects of HIV in Tanzania from the University of Otago Medical School. [7] [8] He was awarded DTM&H in 1995 by the Royal College of Physicians after studying tropical medicine at the London School of Hygiene and Tropical Medicine. Crump trained as both an internist in infectious diseases and as a pathologist in medical microbiology in New Zealand, England, [9] Australia, and the US, being made MRCP(UK) in 1997, FRACP in 1999, FRCPA in 2004, and FRCP in 2009. He served as an Epidemic Intelligence Service Officer with the US Centers for Disease Control and Prevention (US CDC). [1]

Career and research

Crump studies the diagnosis, management, and prevention of infectious causes of fever in the tropics other than malaria, a complex clinical problem that affects many millions annually particularly in low- and middle-income countries. [10] He has advocated for a comprehensive approach to investigating febrile illness as a necessary progression from the traditional disease-specific approach in tropical medicine. [11] He has contributed to describing the problem of malaria over-diagnosis, [12] and also to appreciation of range of neglected causes of fever including invasive bacterial diseases; [13] [14] bacterial zoonoses such as brucellosis, leptospirosis, Q fever, and rickettsioses; [15] [16] [17] [18] and viral diseases such as Rift Valley Fever. [19] [20] [21] Much of his research is trans-disciplinary involving close collaboration between human health experts, veterinarians, ecologists, and social scientists, and following the so-called 'One Health' approach. [22] [23]

Crump has led work characterizing the burden of typhoid fever, [24] [25] paratyphoid fever, [24] [25] and invasive nontyphoidal Salmonella disease [26] [27] that has contributed to diagnosis, management, and prevention efforts for these diseases, including vaccine deployment [28] and vaccine development. [29] He has served in a range of advisory roles to the World Health Organization, including on the burden of invasive salmonelloses to the Foodborne Diseases Epidemiology Reference Group, [30] the WHO Strategic Advisory Group of Experts on Immunization Working Group on Typhoid Vaccines, [31] and the WHO Immunization, Vaccines and Biologicals Technical Advisory Group on Salmonella vaccines. [32]

Crump has a research interest in ethics in global health training, spurred by concern for the unintended consequences of expansion of short-term global health training opportunities in low-resource areas. [33] With Dr. Jeremy Sugarman, Crump co-chaired the Wellcome Trust-funded Working Group on Ethics Guidelines for Global Health Training (WEIGHT) that developed initial guidelines for responsible global health training programs. [34] Crump has also highlighted the value of cosmopolitan principles and the challenges posed by health nationalism in global health responses. [35]

Awards and honors

Crump was awarded the 2005 US CDC James H. Steele Veterinary Public Health Award [36] for outstanding contributions in the investigation, control, or prevention of zoonotic diseases or other animal-related human health problems. In 2012, Crump received the American Society of Tropical Medicine and Hygiene Bailey K. Ashford Medal [37] for distinguished work in tropical medicine. In 2022, Crump was awarded the Royal Society of Tropical Medicine and Hygiene Chalmers Medal for research of outstanding merit in tropical medicine and mentoring of junior investigators. [38] Crump was awarded the 2021 University of Otago Dunedin School of Medicine Dean's Medal for Research Excellence [39] and the 2024 University of Otago Distinguished Research Medal. [40]

Publications

As of December 2024, Crump had published >320 scientific manuscripts, cited >60,000 times. [41] He is a 2020 cross-field Clarivate Highly Cited Researcher, defined as having multiple papers ranked in the top 1% by citations for field and year.

References

  1. 1 2 3 Campus, Otago Medical School-Dunedin. "DSM staff profile". www.otago.ac.nz. Retrieved 2020-08-05.
  2. "John Andrew Crump | Scholars@Duke". scholars.duke.edu. Retrieved 2020-08-05.
  3. Institute, Otago Global Health. "Otago Global Health Institute". www.otago.ac.nz. Retrieved 2020-08-06.
  4. Otago, University of. "Research Centres & Groups". www.otago.ac.nz. Retrieved 2020-08-06.
  5. "Famous Students". www.havelock.school.nz. Archived from the original on 2020-09-22. Retrieved 2020-08-06.
  6. "Going global: Professor John Crump joins Otago's Centre for International Health" (PDF). University of Otago Magazine. June 2012.
  7. Crump, John (2012). HIV prevention, treatment, and care in Sub-Saharan Africa (Doctoral thesis). OUR Archive, University of Otago. hdl:10523/4407.
  8. Otago, University of. "Doctor of Medicine (MD)". www.otago.ac.nz. Retrieved 2020-08-11.
  9. "Professional Diploma in Tropical Medicine & Hygiene". LSHTM. Retrieved 2020-08-09.
  10. "John A. Crump - Google Scholar". scholar.google.com. Retrieved 2020-08-07.
  11. Crump, John A. (2014). "Time for a comprehensive approach to the syndrome of fever in the tropics". Transactions of the Royal Society of Tropical Medicine and Hygiene. 108 (2): 61–62. doi:10.1093/trstmh/trt120. ISSN   1878-3503. PMC   3916746 . PMID   24463580.
  12. Prasad, Namrata; Sharples, Katrina J.; Murdoch, David R.; Crump, John A. (2015). "Community prevalence of fever and relationship with malaria among infants and children in low-resource areas". The American Journal of Tropical Medicine and Hygiene. 93 (1): 178–180. doi:10.4269/ajtmh.14-0646. ISSN   1476-1645. PMC   4497891 . PMID   25918207.
  13. Reddy, Elizabeth A.; Shaw, Andrea V.; Crump, John A. (2010). "Community-acquired bloodstream infections in Africa: a systematic review and meta-analysis". The Lancet. Infectious Diseases. 10 (6): 417–432. doi:10.1016/S1473-3099(10)70072-4. ISSN   1474-4457. PMC   3168734 . PMID   20510282.
  14. Marchello, Christian S.; Dale, Ariella P.; Pisharody, Sruti; Rubach, Matthew P.; Crump, John A. (2019). "A Systematic Review and Meta-analysis of the Prevalence of Community-Onset Bloodstream Infections among Hospitalized Patients in Africa and Asia". Antimicrobial Agents and Chemotherapy. 64 (1). doi:10.1128/AAC.01974-19. ISSN   1098-6596. PMC   7187598 . PMID   31636071.
  15. Crump, John A.; Morrissey, Anne B.; Nicholson, William L.; Massung, Robert F.; Stoddard, Robyn A.; Galloway, Renee L.; Ooi, Eng Eong; Maro, Venance P.; Saganda, Wilbrod; Kinabo, Grace D.; Muiruri, Charles (2013). "Etiology of severe non-malaria febrile illness in Northern Tanzania: a prospective cohort study". PLOS Neglected Tropical Diseases. 7 (7): e2324. doi: 10.1371/journal.pntd.0002324 . ISSN   1935-2735. PMC   3715424 . PMID   23875053.
  16. Halliday, Jo E. B.; Carugati, Manuela; Snavely, Michael E.; Allan, Kathryn J.; Beamesderfer, Julia; Ladbury, Georgia A. F.; Hoyle, Deborah V.; Holland, Paul; Crump, John A.; Cleaveland, Sarah; Rubach, Matthew P. (2020). "Zoonotic causes of febrile illness in malaria endemic countries: a systematic review". The Lancet. Infectious Diseases. 20 (2): e27 –e37. doi:10.1016/S1473-3099(19)30629-2. ISSN   1474-4457. PMC   7212085 . PMID   32006517.
  17. Gibb, John (2015-04-26). "Animals integral to fever solution". Otago Daily Times . Retrieved 2020-08-05.
  18. Rolfe, Robert J.; Sheldon, Sarah W.; Kingry, Luke C.; Petersen, Jeannine M.; Maro, Venance P.; Kinabo, Grace D.; Saganda, Wilbrod; Maze, Michael J.; Halliday, Jo E. B.; Nicholson, William L.; Galloway, Renee L.; Rubach, Matthew P.; Crump, John A. (August 2024). "Metagenomic Detection of Bacterial Zoonotic Pathogens among Febrile Patients, Tanzania, 2007-20091". Emerging Infectious Diseases. 30 (8): 1599–1608. doi:10.3201/eid3008.240529. ISSN   1080-6059. PMC   11286057 . PMID   39043406.
  19. de Glanville, William A.; Allan, Kathryn J.; Nyarobi, James M.; Thomas, Kate M.; Lankester, Felix; Kibona, Tito J.; Claxton, John R.; Brennan, Benjamin; Carter, Ryan W.; Crump, John A.; Halliday, Jo E. B.; Ladbury, Georgia; Mmbaga, Blandina T.; Mramba, Furaha; Nyasebwa, Obed M. (2022-11-01). "An outbreak of Rift Valley fever among peri-urban dairy cattle in northern Tanzania". Transactions of the Royal Society of Tropical Medicine and Hygiene. 116 (11): 1082–1090. doi:10.1093/trstmh/trac076. ISSN   1878-3503. PMC   9623736 . PMID   36040309.
  20. de Glanville, William A.; Nyarobi, James M.; Kibona, Tito; Halliday, Jo E. B.; Thomas, Kate M.; Allan, Kathryn J.; Johnson, Paul C. D.; Davis, Alicia; Lankester, Felix; Claxton, John R.; Rostal, Melinda K.; Carter, Ryan W.; de Jong, Rosanne M. F.; Rubach, Matthew P.; Crump, John A. (October 2022). "Inter-epidemic Rift Valley fever virus infection incidence and risks for zoonotic spillover in northern Tanzania". PLOS Neglected Tropical Diseases. 16 (10): e0010871. doi: 10.1371/journal.pntd.0010871 . ISSN   1935-2735. PMC   9665400 . PMID   36306281.
  21. Madut, Deng B.; Rubach, Matthew P.; Allan, Kathryn J.; Thomas, Kate M.; de Glanville, William A.; Halliday, Jo E. B.; Costales, Cristina; Carugati, Manuela; Rolfe, Robert J.; Bonnewell, John P.; Maze, Michael J.; Mremi, Alex R.; Amsi, Patrick T.; Kalengo, Nathaniel H.; Lyamuya, Furaha (2024-11-13). "Epidemiologic and genomic characterization of an outbreak of Rift Valley fever among humans and dairy cattle in northern Tanzania". The Journal of Infectious Diseases: jiae562. doi:10.1093/infdis/jiae562. ISSN   1537-6613. PMID   39535803.
  22. Halliday, Jo E. B.; Allan, Kathryn J.; Ekwem, Divine; Cleaveland, Sarah; Kazwala, Rudovick R.; Crump, John A. (2015-02-28). "Endemic zoonoses in the tropics: a public health problem hiding in plain sight". The Veterinary Record. 176 (9): 220–225. doi:10.1136/vr.h798. ISSN   2042-7670. PMC   4350138 . PMID   25722334.
  23. Cleaveland, S.; Sharp, J.; Abela-Ridder, B.; Allan, K. J.; Buza, J.; Crump, J. A.; Davis, A.; Del Rio Vilas, V. J.; de Glanville, W. A.; Kazwala, R. R.; Kibona, T. (2017-07-19). "One Health contributions towards more effective and equitable approaches to health in low- and middle-income countries". Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences. 372 (1725). doi:10.1098/rstb.2016.0168. ISSN   1471-2970. PMC   5468693 . PMID   28584176.
  24. 1 2 Crump, John A.; Luby, Stephen P.; Mintz, Eric D. (2004). "The global burden of typhoid fever". Bulletin of the World Health Organization. 82 (5): 346–353. ISSN   0042-9686. PMC   2622843 . PMID   15298225.
  25. 1 2 GBD 2017 Typhoid and Paratyphoid Collaborators including Crump JA (2019). "The global burden of typhoid and paratyphoid fevers: a systematic analysis for the Global Burden of Disease Study 2017". The Lancet. Infectious Diseases. 19 (4): 369–381. doi:10.1016/S1473-3099(18)30685-6. ISSN   1474-4457. PMC   6437314 . PMID   30792131.{{cite journal}}: |last= has generic name (help)CS1 maint: numeric names: authors list (link)
  26. Ao, Trong T.; Feasey, Nicholas A.; Gordon, Melita A.; Keddy, Karen H.; Angulo, Frederick J.; Crump, John A. (2015). "Global burden of invasive nontyphoidal Salmonella disease, 2010(1)". Emerging Infectious Diseases. 21 (6): 941–949. doi:10.3201/eid2106.140999. ISSN   1080-6059. PMC   4451910 . PMID   25860298.
  27. GBD 2017 Non-Typhoidal Salmonella Invasive Disease Collaborators including Crump JA (2019). "The global burden of non-typhoidal salmonella invasive disease: a systematic analysis for the Global Burden of Disease Study 2017". The Lancet. Infectious Diseases. 19 (12): 1312–1324. doi:10.1016/S1473-3099(19)30418-9. ISSN   1474-4457. PMC   6892270 . PMID   31562022.{{cite journal}}: |last= has generic name (help)CS1 maint: numeric names: authors list (link)
  28. World Health Organization (2019). "Typhoid vaccines: WHO position paper, March 2018 - Recommendations". Vaccine. 37 (2): 214–216. doi:10.1016/j.vaccine.2018.04.022. ISSN   1873-2518. PMID   29661581. S2CID   4902671.
  29. "Advancing a GMMA-based vaccine against invasive non-typhoidal salmonellosis through Phase 1 trial in Europe and sub-Saharan Africa". European Commission CORDIS EU research results. Retrieved 7 Aug 2020.
  30. Kirk, Martyn D.; Pires, Sara M.; Black, Robert E.; Caipo, Marisa; Crump, John A.; Devleesschauwer, Brecht; Döpfer, Dörte; Fazil, Aamir; Fischer-Walker, Christa L.; Hald, Tine; Hall, Aron J. (2015). "World Health Organization Estimates of the Global and Regional Disease Burden of 22 Foodborne Bacterial, Protozoal, and Viral Diseases, 2010: A Data Synthesis". PLOS Medicine. 12 (12): e1001921. doi: 10.1371/journal.pmed.1001921 . ISSN   1549-1676. PMC   4668831 . PMID   26633831.
  31. "WHO | SAGE Working Group on Typhoid Vaccines (March 2016 to March 2018)". WHO. Archived from the original on July 26, 2016. Retrieved 2020-08-05.
  32. "Open Calls archive". www.who.int. Retrieved 2024-11-11.
  33. Crump, John A.; Sugarman, Jeremy (2008-09-24). "Ethical considerations for short-term experiences by trainees in global health". JAMA. 300 (12): 1456–1458. doi:10.1001/jama.300.12.1456. ISSN   1538-3598. PMC   3164760 . PMID   18812538.
  34. Crump, John A.; Sugarman, Jeremy; Working Group on Ethics Guidelines for Global Health Training (WEIGHT) (2010). "Ethics and best practice guidelines for training experiences in global health". The American Journal of Tropical Medicine and Hygiene. 83 (6): 1178–1182. doi:10.4269/ajtmh.2010.10-0527. ISSN   1476-1645. PMC   2990028 . PMID   21118918.
  35. Crump, John A.; Vakaoti, Patrick; Moore-Jones, Michael; Tan, Lena; Ergler, Christina R.; Fenton, Elizabeth; Anderson, Emma M. R.; Bremer, Philip J.; Sharples, Katrina J.; Walls, Tony; Quiñones-Mateu, Miguel E.; Kolandai, Komathi; Hadingham, Jacqui; Hill, Philip C.; Knowles, Stephen (2023). "Health nationalism in Aotearoa New Zealand during COVID-19: problems for global health equity". Nature Medicine. 29 (8): 1887–1889. doi:10.1038/s41591-023-02436-y. ISSN   1078-8956. PMID   37464060.
  36. "James H. Steele Veterinary Public Health Award | Attending EIS Conference | Epidemic Intelligence Service | CDC". www.cdc.gov. 2020-06-08. Retrieved 2020-08-06.
  37. "ASTMH - Bailey K. Ashford Medal". www.astmh.org. Retrieved 2020-08-06.
  38. "RSTMH Medals and Awards winners 2022 | RSTMH". rstmh.org. Retrieved 2022-10-26.
  39. "Otago Medical School: Excellence in teaching, research and service". University of Otago. 5 Nov 2021. Retrieved 5 Nov 2021.
  40. Otago, University of (2024-09-19). "Otago honours exceptional researchers". www.otago.ac.nz. Retrieved 2024-11-09.
  41. "John A. Crump". Publons. Retrieved 18 Oct 2023.