U.S. Route 400 is a 481.306-mile-long (774.587 km) mostly east–west U.S. Highway, commissioned in 1994. The highway's western terminus is in Granada, Colorado, at an intersection with US 385. The highway's eastern terminus is southwest of Joplin, Missouri, near Loma Linda, at an interchange with Interstate 44, with which it shares with US 166. It originally ended in Garden City, Kansas; in 1996 it was extended to its current western terminus.
The Kansas Turnpike is a 236-mile (380 km) controlled-access toll road that lies entirely within the US state of Kansas. It runs in a general southwest–northeast direction from the Oklahoma border to Kansas City. It passes through several major Kansas cities, including Wichita, Topeka, and Lawrence. The turnpike is owned and maintained by the Kansas Turnpike Authority (KTA), which is headquartered in Wichita.
K-99 is a state highway in the U.S. state of Kansas. The highway runs 234.473 miles (377.348 km) from Oklahoma State Highway 99 (SH-99) at the Oklahoma state line near Chautauqua north to Nebraska Highway 99 (N-99) at the Nebraska state line in Summerfield. K-99 connects Emporia with several smaller county seats to the south and north, including Sedan, Howard, Eureka, Alma, and Westmoreland while passing through the Flint Hills of eastern Kansas.
K-27 is an approximately 226-mile-long (364 km) north–south state highway that parallels Kansas' western border with Colorado. It is the westernmost north–south state highway in the state. It begins at U.S. Route 56 (US-56) in Elkhart near the Oklahoma state line and travels through the seven counties that border Colorado until reaching its northern terminus north of St. Francis, where it ends at the Nebraska state line. Along the way, it intersects several major highways, including US-160 in Johnson City, US-50 and US-400 in Syracuse, US-40 in Sharon Springs, Interstate 70 (I-70) and US-24 in Goodland, and US-36 in Wheeler. The section from US-40 north to Nebraska, is designated as the Land and Sky Scenic Byway. K-27 changes time zones twice, during its trek through Kansas, the only highway in the state to do so.
K-2 is a 61.516-mile-long (99.000 km) state highway in the south-central portion of the U.S. state of Kansas. Its southern terminus is at an intersection with U.S. Route 281 (US-281) east of Hardtner and its northern terminus is at an intersection with K-42 west of the town of Viola. Along the way K-2 passes through the cities of Kiowa, Hazelton, Anthony and Harper. Between the latter two, it has an overlap with US-160.
K-55 is a 12.049-mile-long (19.391 km) west–east state highway in the U.S. state of Kansas. The highway's western terminus is at U.S. Route 81 (US-81) roughly 11 miles (18 km) north of Wellington and the eastern terminus is at K-15 in Udall. It passes through the city of Belle Plaine.
K-14 is a 219.3-mile-long (352.9 km) north–south state highway which runs through the central part of the U.S. state of Kansas. K-14's southern terminus is at U.S. Highway 160 (US-160) and K-2 in the city of Harper, and the northern terminus is a continuation as Nebraska Highway 14 (N-14) at the Nebraska border by Superior, Nebraska. Along the way it intersects several major east–west highways in the larger cities it passes through, including US-54 and US-400 by Kingman; US-50, K-61 and K-96 by South Hutchinson; K-156 and K-140 by South Ellsworth; Interstate 70 (I-70) and US-40 north of Ellsworth; K-18 in Lincoln; US-24 and K-9 in Beloit; and US-36 east of Mankato. The northern and southern halves of the highway differ fairly significantly in terms of terrain and landscape. The southern half of K-14 travels over fairly flat terrain in the valley of the Arkansas River. Just north of the intersection with K-4 in southern Ellsworth County, K-14 passes into the Smoky Hills region, traveling over a series of broad, rolling hills, providing several scenic vistas of the surrounding countryside. The portion of the highway between Lincoln and Beloit is particularly hilly.
K-61 is a 83.358-mile-long (134.152 km) north–south state highway in central Kansas. K-61's southern terminus is at U.S. Route 54 (US-54) and US-400 on the east side of Pratt. The northern terminus is at Interstate 135 (I-135) and US-81 south of McPherson. The highway travels mostly through rural areas; however, it does pass through South Hutchinson and Hutchinson, where it intersects K-14, K-96, and US-50. K-61 is signed as a north–south but runs in southwest to northeast direction.
K-170 is a 21.759-mile-long (35.018 km) state highway in the U.S. State of Kansas. K-170's western terminus is at K-99 about 12 miles (19 km) north of Emporia, and the eastern terminus is at K-31 on the west side of Osage City, a mile south of the K-31 intersection with U.S. Route 56 (US-56). K-170 provides access, via county roads, to Lyons County State Fishing Lake.
U.S. Route 281 (US-281) is a part of the U.S. Highway System that runs from near the Mexican border north to the International Peace Garden, north of Dunseith, North Dakota, at the Canadian border, where it continues as Highway 10. In the state of Kansas, US-281 is a main north–south highway that runs from the Oklahoma border north to the Nebraska border. US-281 passes within one mile (1.6 km) to the east of the Geographic center of the contiguous United States, which its connected to via K-191 (K-191).
K-42 is a 75.061-mile-long (120.799 km) east–west state highway in the U.S. state of Kansas. Its western terminus is at U.S. Route 281 (US-281) in Sawyer and the eastern terminus is at Interstate 235 (I-235) in Wichita. Along the way K-42 intersects K-14, a major north–south highway, in Rago and K-2 east of Norwich. The highway is a two-lane highway for most of its length with the exception of the section within Wichita, which is a four-lane divided highway.
K-22 is a 3.087-mile-long (4.968 km) north–south highway in the U.S. state of Kansas. Located entirely within Washington County, the route runs from U.S. Route 36 (US-36) north to the city limit of Haddam. A previous designation of the route existed in the 1930s from Wichita to Topeka, but was deprecated. The current alignment was designated in the 1940s.
K-23 is a 199.117-mile-long (320.448 km) south–north state highway in the U.S. State of Kansas. It starts as a continuation of Oklahoma State Highway 23 (SH-23) and it runs northward to U.S. Route 83 (US-83) and K-383 near Selden. Along the way it intersects several major east–west highways, including US-54 and US-160 in Meade, US-50 and US-400 in Cimarron, US-56 near Montezuma, K-4 near Healy, and Interstate 70 (I-70) and US-40 south of Grainfield. All but about 1.5 miles (2.4 km) of K-23's alignment is maintained by the Kansas Department of Transportation. The entire section within Cimarron is maintained by the city and a section in Hoxie from Utah Street to Queen Street is maintained by the city.
K-25 is a 238.259-mile-long (383.441 km) south–north state highway in the U.S. State of Kansas. K-25 runs from Oklahoma State Highway 136 (SH-136) at the Oklahoma State Line to Nebraska Highway 25 (N-25) at the Nebraska border, running through Leoti, Colby, and Atwood plus many more towns along the way.
K-51 is an approximately 79-mile-long (127 km) east–west state highway in the southwestern part of the U.S. state of Kansas. K-51 begins at the Colorado state line as a continuation of County Road M and travels eastward through portions of Morton, Stevens, and Seward counties before ending at U.S. Route 83 (US-83) north of Liberal. Along the way, it runs concurrently with US-56 from Rolla to Hugoton. Although K-51 travels through mostly rural farmlands, it does pass through the cities of Richfield, Rolla and Hugoton. The highway is also a two-lane road most of its length with the exception of short sections within Rolla and Hugoton, where it is four lanes.
K-47 is an approximately 61.6-mile-long (99.1 km) state highway in the U.S. state of Kansas. It is an east-west route, and connects small towns and cities in southeast Kansas. K-47's western terminus is at the Fredonia city limits, just west of the intersection with U.S. Route 400 (US-400). The eastern terminus is US-69 in Franklin. Along the way, it intersects several major highways including US-75 in Altoona, US-59 south of Erie, and K-7 in Girard. With the exception of the cities K-47 passes through, the highway travels through rural farmland.
K-49 is a 35.354-mile-long (56.897 km) north–south state highway in the U.S. state of Kansas. K-49 begins at U.S. Route 81 (US-81) in Caldwell, and runs north to K-42 in Viola. Along the way, K-49 has a brief overlap with US-160 south of Conway Springs. The majority of the route exists in Sumner County, with only a mile existing in Sedgwick County.
K-57 is a 31.2-mile-long (50.2 km) north–south state highway in the U.S. state of Kansas. K-57's southern terminus is at K-4 in Dwight. The northern terminus is at U.S. Route 77 (US-77) north of Junction City. The highway intersects Interstate 70 (I-70) in Grandview Plaza; at the intersection, I-70 is also the route of US-40 and K-18. K-57 overlaps US-40 Business from I-70 northbound to North Washington Street in Junction City. North of Junction City, the highway passes through Milford State Park where it crosses the Milford Lake Dam. The majority of the highway is two-lanes except for the section from J Hill Road in Grandview Plaza to the junction with K-244 which is four-lanes.
K-116 is a 26.146-mile-long (42.078 km) state highway in the northeast part of the U.S. state of Kansas. K-116's western terminus is at U.S. Route 75 (US-75) and K-16 in Holton, and the eastern terminus is at US-59 southwest of Atchison. The first 3.5 miles (5.6 km) of K-116 is co-designated with K-16. Also a brief section is co-designated with US-159 near the eastern terminus. The highway travels mostly through rural farmland and is a two-lane highway for its entire length.
K-190 is a 24.172-mile-long (38.901 km) east–west state highway in the U.S. state of Kansas. K-190's western terminus is at U.S. Route 160 (US-160) east of the community of Hickok, and the eastern terminus is at US-83 and US-160 south of the city of Sublette. K-190 travels mostly through flat rural farmland, however it does run through the city of Satanta where it is co-designated as US-56.
US 54 / K-96 / US 81 / K-15 in Wichita 
US 75 / US 40 / K-4 / K-10 in Topeka 
