Katrina Mealey | |
---|---|
Born | New Mexico, USA |
Spouse | Robert Mealey (m. 1987) |
Academic background | |
Education | BS, 1986, University of New Mexico DVM, 1990, Colorado State University PhD, 1998, Texas A&M University |
Thesis | Novel mechanisms for MDR induction and modulation (1998) |
Academic work | |
Institutions | Washington State University |
Katrina Ann Mealey (nee Larson) is an American veterinary pharmacologist. She is a Regents Professor and Richard L. Ott Endowed Chair in Small Animal Medicine and Research at Washington State University.
Mealey was born and raised in New Mexico to parents Maria Gonzales and Wayne R. Larson. She completed her Bachelor of Science degree at the University of New Mexico before marrying her husband,Robert Mealey,and enrolling together at Colorado State University for their DVM. [1] Following her DVM,Mealey completed two internships and a residency before completing her PhD at Texas A&M University in 1998. [2]
Following her PhD,Mealey accepted a faculty position at Washington State University (WSU). While leading a group of WSU researchers,she discovered that a gene mutation called MDR1 predisposed herding dogs—collies to react violently to a deworming pill. [3] Based on this discovery,Mealey developed a clinical test for the mutation based on blood samples and cheek swabs from at least 25 unrelated dogs of every one of the 150-plus breeds. [4] [5] While conducting this trial,she also filed for her first US Patent for her diagnostic test. [3] As a result of her research,Mealey was one of the recipients of the 2012 Pfizer Animal Health Award for Research Excellence. [6]
Based on her clinical trials,Mealey established the first veterinary-based dedicated research effort towards individualized medicine in animals in 2013. [7] Her work on identifying why certain dog breeds suffer deadly drug reactions led her to receive a 2013 Women to Watch in Life Science Award from the Washington Biotechnology and Biomedical Association. [8] She was later recognized in 2016 with an election to the National Academy of Inventors for her invention of a genetic test that detects the MDR-1 mutation. [9] Mealey also received the 2019 Lloyd E. Davis Award in recognition of her "outstanding achievements in research,teaching,and professional service in veterinary pharmacology." [10]
In July 2020,Mealey was elected to the Washington State Academy of Sciences for her expertise in pharmacogenetics that has benefited veterinary medicine both locally and worldwide. [11] She then earned funding to support technology to allow for her research team to predetermine whether a drug would cause issues for dogs and cats with the gene mutation. [12] While conducting her research,Mealey also partook in the national Promotion and Tenure,Innovation and Entrepreneurship Coalition where she advocated for more value to be placed on innovation,entrepreneurship and other forms of scholarly impact. [13]
In January 2022,Mealey was recognized with an election to the American Association for the Advancement of Science for her contributions to research and leadership in the areas of food labeling,food quality,and product reputation. [14] Following this,Mealey and her research team in the Program in Individualized Medicine at WSU developed a test to detect the MDR1 mutation in cats. [15]
During her off-time,Mealey is an avid runner. She ran in the 2013 Boston Marathon,where she finished with a time of 3:49:41. [16]
The Labrador Retriever or simply Labrador is a British breed of retriever gun dog. It was developed in the United Kingdom from St. John's water dogs imported from the colony of Newfoundland,and was named after the Labrador region of that colony. It is among the most commonly kept dogs in several countries,particularly in the European world.
The Border Collie is a British breed of herding dog of the collie type of medium size. It originates in the region of the Anglo-Scottish border,and descends from the traditional sheepdogs once found all over the British Isles. It is kept mostly as a working sheep-herding dog or as a companion animal. It competes with success in sheepdog trials. It has been claimed that it is the most intelligent breed of dog.
The Shetland Sheepdog,also known as the Sheltie,is a breed of herding dog that originated in the Shetland Islands of Scotland. It was formally recognized by the Kennel Club in 1909. It was originally called the Shetland Collie,but this caused controversy amongst Rough Collie breeders of the time,so the name was changed. It is a small dog,clever,vocal,willing to please,and trustworthy.
Collies form a distinctive type of herding dogs,including many related landraces and standardized breeds. The type originated in Scotland and Northern England. Collies are medium-sized,fairly lightly-built dogs,with pointed snouts. Many types have a distinctive white color over the shoulders. Collies are very active and agile,and most types of collies have a very strong herding instinct. Collie breeds have spread through many parts of the world,and have diversified into many varieties,sometimes mixed with other dog types.
The Australian Shepherd is a breed of herding dog from the United States. The name of the breed is technically a misnomer,as it was developed in California in the 19th century. It is believed to have its origins in sheepdog breeds from northwest Spain,as well as collies imported,alongside sheep,from Australia and New Zealand;the breed reportedly took its name from this trade. Originally used solely as a herding dog,the Australian Shepherd has become one of the most popular companion dog breeds in North America.
The Smooth Collie is a breed of dog developed originally for herding. It is a short-coated version of the Rough Collie of Lassie fame. Some breed organisations consider the smooth-coat and rough-coat dogs to be variations of the same breed.
The New York State College of Veterinary Medicine at Cornell University is a statutory college of veterinary medicine at Cornell University,in Ithaca,New York. Founded in 1894,it is the first statutory college of the State University of New York (SUNY) system.
The Old English Sheepdog is a large breed of dog that emerged in England from early types of herding dog. Obsolete names for the breed include Shepherd's Dog and bob-tailed sheep-dog. The nickname Bob-tail originates from how dogs of the breed traditionally had their tails docked. Old English Sheepdogs can grow very long coats with fur covering the face and eyes and do not shed unless brushed.
The University of California,Davis,School of Veterinary Medicine is the largest veterinary school in the United States. Established in 1948,the school is the primary health resource for California's animal populations. In 2020,the school was again ranked first in the United States by U.S. News &World Report and in 2022,ranked second in the world by QS World University Rankings. The school is located in the southwest corner of the main campus of the University of California,Davis. The current dean of veterinary medicine is Dr. Mark Stetter.
Acepromazine,acetopromazine,or acetylpromazine is a phenothiazine derivative antipsychotic drug. It was used in humans during the 1950s as an antipsychotic,but is now almost exclusively used on animals as a sedative and antiemetic. A closely related analogue,chlorpromazine,is still used in humans.
The McNab Dog,also called the McNab Shepherd or McNab Collie is a herding dog that originated in Hopland,Mendocino County,Northern California. The McNab was bred to withstand the tough conditions found in California such as heat,burrs,foxtails,and rugged terrain. Until recently,the McNab was little known outside California,but in last three decades have seen a gain in popularity and geographic dispersal of the breed.
The Virginia–Maryland College of Veterinary Medicine is the veterinary school of Virginia Tech and the University of Maryland,College Park - both of which are public research universities in the Commonwealth of Virginia and the State of Maryland,respectively. The college was created as a joint venture of the two universities and their respective state governments in order to fill the need for veterinary medicine education in both states. Students from both states are considered "in-state" students for admissions and tuition purposes.
The Center for Veterinary Medicine (CVM) is a branch of the U.S. Food and Drug Administration (FDA) that regulates the manufacture and distribution of food,food additives,and drugs that will be given to animals. These include animals from which human foods are derived,as well as food additives and drugs for pets or companion animals. CVM is responsible for regulating drugs,devices,and food additives given to,or used on,over one hundred million companion animals,plus millions of poultry,cattle,swine,and minor animal species. Minor animal species include animals other than cattle,swine,chickens,turkeys,horses,dogs,and cats.
The Silken Windhound is an American breed of sighthound. Like most sighthounds,Silkens are noted coursers.
Cerebellar abiotrophy (CA),also called cerebellar cortical abiotrophy (CCA),is a genetic neurological disease in animals,best known to affect certain breeds of horses,dogs and cats. It can also develop in humans. It develops when the neurons known as Purkinje cells,located in the cerebellum of the brain,begin to die off. These cells affect balance and coordination. They have a critical role to play in the brain. The Purkinje layer allows communication between the granular and molecular cortical layers in the cerebellum. Put simply,without Purkinje cells,an animal loses its sense of space and distance,making balance and coordination difficult. People with damage to the cerebellum can experience symptoms like unsteady gait,poor muscle control,and trouble speaking or swallowing.
Leslie A. Lyons is an American geneticist. She is a professor of comparative medicine and the director of the Feline Genetics and Comparative Medicine Laboratory at the University of Missouri College of Veterinary Medicine. Lyons is one of the world’s foremost experts in feline genetics. Her work has advanced the understanding of the feline genome,highlighting its similarity to the human genome and its potential in precision medicine,which she frequently emphasizes while advocating for the use of cats as model organisms in genetic research.
Hypoadrenocorticism in dogs,or,as it is known in people,Addison's disease,is an endocrine system disorder that occurs when the adrenal glands fail to produce enough hormones for normal function. The adrenal glands secrete glucocorticoids such as cortisol and mineralocorticoids such as aldosterone;when proper amounts of these are not produced,the metabolic and electrolyte balance is upset. Mineralocorticoids control the amount of potassium,sodium,and water in the body. Hypoadrenocorticism is fatal if left untreated.
Pancreatitis is a common condition in cats and dogs. Pancreatitis is inflammation of the pancreas that can occur in two very different forms. Acute pancreatitis is sudden,while chronic pancreatitis is characterized by recurring or persistent form of pancreatic inflammation. Cases of both can be considered mild or severe. It is currently undecided whether chronic pancreatitis is a distinct disease or a form of acute pancreatitis. Other forms such as auto-immune and hereditary pancreatitis are presumed to occur but there existence has not been proven.
Ann Trommershausen Bowling was an American scientist who was one of the world's leading geneticists in the study of horses,conducting research in the areas of molecular genetics and cytogenetics. She was a major figure in the development of testing to determine animal parentage,first with blood typing in the 1980s and then DNA testing in the 1990s. She later became known for her studies of hereditary diseases in horses and equine coat color genetics,as well as research on horse evolution and the development of horse breeds. She studied the population genetics of feral horses,did considerable work to help preserve the Przewalski's horse,and was one of the founding members of the international project to map the horse genome. She was an adjunct professor at the University of California,Davis (UCD),and at the time of her death in 2000 was the executive associate director of the Veterinary Genetics Laboratory (VGL) there. Her unexpected death on December 8,2000,at age 57 was attributed to a massive stroke.
Amy K. LeBlanc is an American veterinary oncologist and biologist researching animal modeling for development of new cancer drugs and imaging agents,and identification of imaging biomarkers,development and optimization of PET imaging hardware and imaging protocols. She is a senior scientist in the molecular imaging program and director of the Comparative Oncology Program at the National Cancer Institute. LeBlanc was previously an associate professor at the University of Tennessee College of Medicine and College of Veterinary Medicine.