LIPID MAPS

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LIPID MAPS
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Description Lipidomics
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Primary citation PMID   17584797
Release date2003
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Websitewww.lipidmaps.org

LIPID MAPS (Lipid Metabolites and Pathways Strategy) is a web portal designed to be a gateway to Lipidomics resources. The resource has spearheaded a classification of biological lipids, dividing them into eight general categories. [1] LIPID MAPS provides standardised methodologies for mass spectrometry analysis of lipids, e.g. [2] [3] [4]

LIPID MAPS has been cited as evidence of a growing appreciation of the study of lipid metabolism [5] and the rapid development and standardisation of the lipidomics field [6] [7]

Key LIPID MAPS resources include:

Tools available from LIPID MAPS enable scientists to identify likely lipids in their samples from mass spectrometry data, a common method to analyse lipids in biological specimens. In particular, LipidFinder [10] enables analysis of MS data. Tutorials and educational material on lipids are also available at the site. [11]

In January 2020, LIPID MAPS became an ELIXIR service. [12] and in 2024 a core data resource. In addition, it joined Global Biodata Coalition as a core biodata resource. [13]

History

LIPID MAPS was founded in 2003 with NIH funding. [14] LIPID MAPS was previously funded by a multi-institutional grant from Wellcome, and is now funded under an MRC Partnership award, held jointly by University of Cardiff led by Prof Valerie O'Donnell, the Babraham Institute, UCSD and Swansea University, and The University of Edinburgh. Wakelam's obituary describes LIPID MAPS as unifying the field of lipidomics. [15]

LIPID MAPS is sponsored by Cayman Chemical and Avanti Polar lipids

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References

  1. ↑ Fahy E, Subramaniam S, Murphy RC, Nishijima M, Raetz CR, Shimizu T, Spener F, van Meer G, Wakelam MJ, Dennis EA (April 2009). "Update of the LIPID MAPS comprehensive classification system for lipids". Journal of Lipid Research. 50 Suppl (S1): S9-14. doi: 10.1194/jlr.R800095-JLR200 . PMC   2674711 . PMID   19098281.
  2. ↑ Valeria Pereira Serafim P, Figueiredo JR, de Adiel G, Vitor Felipe A, Guimaraes Lo Turco E, Silva, Manoukian Forones N (2019). "STUDY OF LIPID BIOMARKERS OF PATIENTS WITH POLYPS AND COLORECTAL CÂNCER". Arquivos de Gastroenterologia. 56 (4): 399–404. doi: 10.1590/S0004-2803.201900000-80 . PMID   31800736.
  3. ↑ Zheng H, Yang R, Wang Z, Wang J, Zhang J, Sun H (2020). "Characterization of pharmaceutic structured triacylglycerols by high‐performance liquid chromatography/tandem high‐resolution mass spectrometry and its application to structured fat emulsion injection". Rapid Communications in Mass Spectrometry. 34 (1): e8557. doi:10.1002/rcm.8557. PMID   31429125.
  4. ↑ Sasaki H, White SH (2008). "Aggregation Behavior of an Ultra-Pure Lipopolysaccharide that Stimulates TLR-4 Receptors". Biophysical Journal. 95 (2): 986–993. Bibcode:2008BpJ....95..986S. doi:10.1529/biophysj.108.129197. PMC   2440428 . PMID   18375521.
  5. ↑ Muralikrishna Adibhatla R, Hatcher JF (2007). "Role of lipids in brain injury and diseases". Future Lipidology. 2 (4): 403–422. doi:10.2217/17460875.2.4.403. PMC   2174836 . PMID   18176634.
  6. ↑ "Phat on potential, lipidomics is gaining weight". Eureka Alert. 10 January 2019. Retrieved 10 June 2020.
  7. ↑ "Lipidomics – A Niche but Rapidly Growing Field". Technology Networks. 11 September 2019. Retrieved 10 June 2020.
  8. ↑ Sud M, Fahy E, Cotter D, et al. (January 2007). "LMSD: LIPID MAPS structure database". Nucleic Acids Res. 35 (Database issue): D527–32. doi:10.1093/nar/gkl838. PMC   1669719 . PMID   17098933.
  9. ↑ Cotter D, Maer A, Guda C, Saunders B, Subramaniam S (January 2006). "LMPD: LIPID MAPS proteome database". Nucleic Acids Res. 34 (90001): D507–10. doi:10.1093/nar/gkj122. PMC   1347484 . PMID   16381922.
  10. ↑ Fahy E, Alvarez-Jarreta J, Brasher CJ, Nguyen A, Hawksworth JI, Rodrigues P, Meckelmann S, Allen SM, O'Donnell VB (2019). "LipidFinder on LIPID MAPS: peak filtering, MS searching and statistical analysis for lipidomics". Bioinformatics. 35 (4): 685–687. doi:10.1093/bioinformatics/bty679. PMC   6378932 . PMID   30101336.
  11. ↑ Sud M, Fahy E, Cotter D, Dennis EA, Subramaniam S (December 2011). "LIPID MAPS-Nature Lipidomics Gateway: An Online Resource for Students and Educators Interested in Lipids". Journal of Chemical Education. 89 (2): 291–292. doi:10.1021/ed200088u. PMC   3995124 . PMID   24764601.
  12. ↑ "Service list". elixir-europe.org. Retrieved 10 June 2020.
  13. ↑ "Global data resource LIPID MAPS awarded two international badges of excellence" . Retrieved 25 July 2024.
  14. ↑ Conroy, Matthew J; Andrews, Robert M; Andrews, Simon; Cockayne, Lauren; Dennis, Edward A; Fahy, Eoin; Gaud, Caroline; Griffiths, William J; Jukes, Geoff; Kolchin, Maksim; Mendivelso, Karla; Lopez-Clavijo, Andrea F; Ready, Caroline; Subramaniam, Shankar; O'Donnell, Valerie B (19 October 2023). "LIPID MAPS: update to databases and tools for the lipidomics community". Nucleic Acids Research. doi: 10.1093/nar/gkad896 . PMC   10767878 .
  15. ↑ Ferry, Georgina (24 April 2020). "Michael Wakelam obituary". The Guardian. Manchester. Retrieved 10 June 2020.
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