LSG1

LSG1
Identifiers
Aliases	LSG1 , large 60S subunit nuclear export GTPase 1
External IDs	OMIM: 610780; MGI: 107236; HomoloGene: 5917; GeneCards: LSG1; OMA:LSG1 - orthologs
Gene location (Human)
Chr.	Chromosome 3 (human)
End	194,672,463 bp
Gene location (Mouse)
Chr.	Chromosome 16 (mouse)
End	30,406,410 bp
RNA expression pattern
	Top expressed in
	rectum; ; right lobe of liver; ; Achilles tendon; ; skin of abdomen; ; body of pancreas; ; upper lobe of left lung; ; lymph node; ; left uterine tube; ; nipple; ; islet of Langerhans;
	Top expressed in
	spermatocyte; ; spermatid; ; morula; ; yolk sac; ; otic placode; ; seminiferous tubule; ; neural tube; ; maxillary prominence; ; somite; ; ganglionic eminence;
	More reference expression data
	; ;
	More reference expression data
Gene ontology
Molecular function	nucleotide binding ; GTP binding ; hydrolase activity ; GTPase activity ;
Cellular component	Cajal body ; endoplasmic reticulum ; nucleus ; membrane ; cytoplasm ; nuclear body ; cytosol ;
Biological process	protein transport ; nuclear export ; ribosome biogenesis ; transport ;
	Sources:Amigo / QuickGO
Orthologs
	55341
	224092
	ENSG00000041802
	ENSMUSG00000022538
	Q9H089
	Q3UM18
	NM_018385
	NM_178069
	NP_060855
	NP_835170
	Wikidata
View/Edit Human	View/Edit Mouse

Last updated June 03, 2024

Large subunit GTPase 1 homolog is an enzyme that in humans is encoded by the LSG1 gene.^[5]^[6]

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References

1 2 3 GRCh38: Ensembl release 89: ENSG00000041802 – Ensembl, May 2017
1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000022538 – Ensembl, May 2017
↑ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ Wiemann S, Weil B, Wellenreuther R, Gassenhuber J, Glassl S, Ansorge W, Bocher M, Blocker H, Bauersachs S, Blum H, Lauber J, Dusterhoft A, Beyer A, Kohrer K, Strack N, Mewes HW, Ottenwalder B, Obermaier B, Tampe J, Heubner D, Wambutt R, Korn B, Klein M, Poustka A (Mar 2001). "Toward a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs". Genome Res. 11 (3): 422–35. doi:10.1101/gr.GR1547R. PMC 311072 . PMID 11230166.
↑ "Entrez Gene: LSG1 large subunit GTPase 1 homolog (S. cerevisiae)".

Maruyama K, Sugano S (1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides". Gene. 138 (1–2): 171–4. doi:10.1016/0378-1119(94)90802-8. PMID 8125298.
Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, et al. (1997). "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library". Gene. 200 (1–2): 149–56. doi:10.1016/S0378-1119(97)00411-3. PMID 9373149.
Hartley JL, Temple GF, Brasch MA (2001). "DNA cloning using in vitro site-specific recombination". Genome Res. 10 (11): 1788–95. doi:10.1101/gr.143000. PMC 310948 . PMID 11076863.
Simpson JC, Wellenreuther R, Poustka A, et al. (2001). "Systematic subcellular localization of novel proteins identified by large-scale cDNA sequencing". EMBO Rep. 1 (3): 287–92. doi:10.1093/embo-reports/kvd058. PMC 1083732 . PMID 11256614.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi: 10.1073/pnas.242603899 . PMC 139241 . PMID 12477932.
Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi: 10.1038/ng1285 . PMID 14702039.
Wiemann S, Arlt D, Huber W, et al. (2004). "From ORFeome to biology: a functional genomics pipeline". Genome Res. 14 (10B): 2136–44. doi:10.1101/gr.2576704. PMC 528930 . PMID 15489336.
Reynaud EG, Andrade MA, Bonneau F, et al. (2006). "Human Lsg1 defines a family of essential GTPases that correlates with the evolution of compartmentalization". BMC Biol. 3: 21. doi: 10.1186/1741-7007-3-21 . PMC 1262696 . PMID 16209721.
Mehrle A, Rosenfelder H, Schupp I, et al. (2006). "The LIFEdb database in 2006". Nucleic Acids Res. 34 (Database issue): D415–8. doi:10.1093/nar/gkj139. PMC 1347501 . PMID 16381901.

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[refGRCh38Ensembl-1] 1 2 3 GRCh38: Ensembl release 89: ENSG00000041802 – Ensembl, May 2017

[refGRCm38Ensembl-2] 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000022538 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid11230166-5] Wiemann S, Weil B, Wellenreuther R, Gassenhuber J, Glassl S, Ansorge W, Bocher M, Blocker H, Bauersachs S, Blum H, Lauber J, Dusterhoft A, Beyer A, Kohrer K, Strack N, Mewes HW, Ottenwalder B, Obermaier B, Tampe J, Heubner D, Wambutt R, Korn B, Klein M, Poustka A (Mar 2001). "Toward a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs". Genome Res. 11 (3): 422–35. doi:10.1101/gr.GR1547R. PMC 311072 . PMID 11230166.

[entrez-6] "Entrez Gene: LSG1 large subunit GTPase 1 homolog (S. cerevisiae)".

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LSG1

Related Research Articles

References

Further reading