LSG1

LSG1
Identifiers
Aliases	LSG1 , large 60S subunit nuclear export GTPase 1
External IDs	OMIM: 610780; MGI: 107236; HomoloGene: 5917; GeneCards: LSG1; OMA:LSG1 - orthologs
Gene location (Human) Chr. Chromosome 3 (human) [1] Band 3q29 Start 194,640,791 bp [1] End 194,672,463 bp [1]
Gene location (Mouse) Chr. Chromosome 16 (mouse) [2] Band 16 B2|16 21.34 cM Start 30,379,312 bp [2] End 30,406,410 bp [2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in granulocyte rectum right lobe of liver Achilles tendon skin of abdomen body of pancreas skin of leg upper lobe of left lung lymph node right ovary Top expressed in spermatocyte tail of embryo genital tubercle epiblast spermatid ventricular zone embryo morula morula yolk sac More reference expression data BioGPS More reference expression data
Gene ontology Molecular function nucleotide binding GTP binding hydrolase activity GTPase activity Cellular component Cajal body endoplasmic reticulum nucleus membrane cytoplasm nuclear body cytosol Biological process protein transport nuclear export ribosome biogenesis transport Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 55341 224092 Ensembl ENSG00000041802 ENSMUSG00000022538 UniProt Q9H089 Q3UM18 RefSeq (mRNA) NM_018385 NM_178069 RefSeq (protein) NP_060855 NP_835170 Location (UCSC) Chr 3: 194.64 – 194.67 Mb Chr 16: 30.38 – 30.41 Mb PubMed search [3] [4]
Wikidata
View/Edit Human View/Edit Mouse

Large subunit GTPase 1 homolog is an enzyme that in humans is encoded by the LSG1 gene. ^{[5] [6]}

References

1. GRCh38: Ensembl release 89: ENSG00000041802 – Ensembl, May 2017
2. GRCm38: Ensembl release 89: ENSMUSG00000022538 – Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. Wiemann S, Weil B, Wellenreuther R, Gassenhuber J, Glassl S, Ansorge W, Bocher M, Blocker H, Bauersachs S, Blum H, Lauber J, Dusterhoft A, Beyer A, Kohrer K, Strack N, Mewes HW, Ottenwalder B, Obermaier B, Tampe J, Heubner D, Wambutt R, Korn B, Klein M, Poustka A (Mar 2001). "Toward a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs". Genome Res. 11 (3): 422–35. doi:10.1101/gr.GR1547R. PMC   311072 . PMID   11230166.
6. "Entrez Gene: LSG1 large subunit GTPase 1 homolog (S. cerevisiae)".

Further reading

• Maruyama K, Sugano S (1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides". Gene. 138 (1–2): 171–4. doi:10.1016/0378-1119(94)90802-8. PMID   8125298.
• Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, et al. (1997). "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library". Gene. 200 (1–2): 149–56. doi:10.1016/S0378-1119(97)00411-3. PMID   9373149.
• Hartley JL, Temple GF, Brasch MA (2001). "DNA cloning using in vitro site-specific recombination". Genome Res. 10 (11): 1788–95. doi:10.1101/gr.143000. PMC   310948 . PMID   11076863.
• Simpson JC, Wellenreuther R, Poustka A, et al. (2001). "Systematic subcellular localization of novel proteins identified by large-scale cDNA sequencing". EMBO Rep. 1 (3): 287–92. doi:10.1093/embo-reports/kvd058. PMC   1083732 . PMID   11256614.
• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi: 10.1073/pnas.242603899 . PMC   139241 . PMID   12477932.
• Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi: 10.1038/ng1285 . PMID   14702039.
• Wiemann S, Arlt D, Huber W, et al. (2004). "From ORFeome to biology: a functional genomics pipeline". Genome Res. 14 (10B): 2136–44. doi:10.1101/gr.2576704. PMC   528930 . PMID   15489336.
• Reynaud EG, Andrade MA, Bonneau F, et al. (2006). "Human Lsg1 defines a family of essential GTPases that correlates with the evolution of compartmentalization". BMC Biol. 3: 21. doi: 10.1186/1741-7007-3-21 . PMC   1262696 . PMID   16209721.
• Mehrle A, Rosenfelder H, Schupp I, et al. (2006). "The LIFEdb database in 2006". Nucleic Acids Res. 34 (Database issue): D415–8. doi:10.1093/nar/gkj139. PMC   1347501 . PMID   16381901.