Avesta Ketamine and Wellness (Co-CEO and Founder) Georgetown University (Professor Emerita)
Notable work
Her work on rat models, investigating the effects of acupuncture on the hypothalamic–pituitary–adrenal axis (HPA axis) hormones as markers for chronic stress.[1][2] Publishing clinical research on the effectiveness of ketamine as an antidepressant, including the use of adjunct treatments like intravenous glutathione.[3]
Dr. Ladan Eshkevari, PhD, CRNA, L.Ac., FAAN, is an Iranian-American healthcare professional and academic.[4][5]
She is the Co-CEO and Founder of Avesta Ketamine and Wellness, a clinic specializing in ketamine therapy for mental health and chronic pain.[6][7]
Eshkevari is a member of the American Association of Nurse Anesthesiology (AANA) and also served as the Editor-In-Chief of its peer-reviewed, bimonthly academic journal, Journal of the American Association of Nurse Anesthesiology (AANA Journal).[8]
Ladan Eshkevari was born in Iran and lived in India during her formative years, attending the British School till the age of 15. She moved to the United States with her family as a teenager.[10]
She holds a BS (Hons.) in Nursing degree from the University of Maryland, Baltimore, an MS in Anesthesia degree from the Columbia University School of Nursing, a PhD in Physiology and Biophysics from Georgetown University, has a Diplomate degree in Traditional Chinese Medicine and Acupuncture from Maryland Institute of Traditional Chinese Medicine and a Certification in Corporate Executive Leadership from Georgetown University.[11][12]
Career
Eshkevari started her career as a nurse during the AIDS epidemic in the United States.[13]
Eshkevari is a professor emerita at Georgetown University and between 1997 and 2022, she has held various positions at Georgetown University, such as a Nurse Anesthetist (1997–2010), an Associate Professor (1997–2022), Professor (2022) and the Program Director of the university's Doctor of Nurse Anesthesia Practice program (2017–2022).[17]
She serves on various national boards in the United States such as the Medicare Evidence Development and Coverage Advisory Committee.[18] She has also served as the President of the District of Columbia Association of Nurse Anesthetists, was co-chair of the Education Committee of the Board of Nursing in the District appointed by Mayor Anthony A. Williams in 2005, and continues to serve on its Advance Practice Advisory Panel. She is a former chair of the American Association of Nurse Anesthesiology Foundation Board of Trustees.[19]
Since 2018, Eshkevari has been the Founder and Co-CEO of Avesta Ketamine and Wellness, a group of clinics providing ketamine infusion therapy for conditions such as depression, anxiety, and chronic pain in the Washington metropolitan area.[20][21][22][23][24][25][26]
Research
Eshkevari's areas of research include identifying physiologic markers for chronic stress and pain that are modulated by acupuncture, research on different anesthesia-related topics, and clinical research on ketamine's effects as an antidepressant.[27]
She has also published clinical research on the effectiveness of ketamine as an antidepressant, including the use of adjunct treatments like intravenous glutathione.[33]
Personal life
Eshkevari is of Iranian origin.[34] She is fluent in English, Spanish and Persian.[35]
Selected Publications
Journal Articles
Acupuncture and pain: a review of the literature (2003)[36]
Use of acupuncture for chronic pain: Optimizing clinical practice (2005) [37][38]
Occurrence and removal of a knotted pulmonary artery catheter: a case report (2007)[39]
Acupuncture at ST36 prevents chronic stress-induced increases in neuropeptide Y in rat (2012)[40]
Propofol and Ketamine for Targeted Muscle Reinnervation after Limb Amputation (2013)[41]
Acupuncture blocks cold stress-induced increases in the hypothalamus pituitary adrenal axis (HPA) in the rat (2013) [42]
Effects of acupuncture, RU-486 on the hypothalamic-pituitary-adrenal axis in chronically stressed adult male rats (2015)[44]
Impact of COVID-19 Pandemic on Certified Registered Nurse Anesthetist Practice (2021)[45]
Efficacy of addition of the anti-inflammatory, IV glutathione to standard ketamine IV therapy in major depressive disorder (2024) [46]
Presentations
Effects of electroacupuncture (EA) on stress-induced increases in central HP axis hormones, 2011. Washington DC: FASEB J.[47]
Effects of electroacupuncture (EA) on cold stress-induced increases in peripheral and central (paraventricular nucleus-PVN) HP axis hormones, 2011. Washington DC: The American Acupuncturist.[48]
↑Eshkevari, Ladan; Sales, Michelle; Collins, Christina; Totoraitis, Julia; Donohue, Lindsay; Bowman-Dalley, Carrie; Breggman, Bejamin; Negro, Paulo; Gordon, Stephanie; Estrada, Christian (July 2024). "Efficacy of addition of the anti-inflammatory, IV glutathione to standard ketamine IV therapy in major depressive disorder". Psychiatry Research. 337 (115949). doi:10.1016/j.psychres.2024.115949.
↑Eshkevari, Ladan; Mulroney, Susan E.; Egan, Rupert; Lao, Lixing (2015). "Effects of acupuncture, RU-486 on the hypothalamic-pituitary-adrenal axis in chronically stressed adult male rats". Endocrinology. 156 (5): 1737–1746. doi:10.1210/en.2015-1018.
↑Eshkevari, Ladan; Sales, Michelle; Collins, Christina; Totoraitis, Julia; Donohue, Lindsay; Bowman-Dalley, Carrie; Breggman, Bejamin; Negro, Paulo; Gordon, Stephanie; Estrada, Christian (July 2024). "Efficacy of addition of the anti-inflammatory, IV glutathione to standard ketamine IV therapy in major depressive disorder". Psychiatry Research. 337 (115949). doi:10.1016/j.psychres.2024.115949.
↑Eshkevari, Ladan; Mulroney, Susan E.; Egan, Rupert; Lao, Lixing (2015). "Effects of acupuncture, RU-486 on the hypothalamic-pituitary-adrenal axis in chronically stressed adult male rats". Endocrinology. 156 (5): 1737–1746. doi:10.1210/en.2015-1018.
↑Eshkevari, Ladan; Sales, Michelle; Collins, Christina; Totoraitis, Julia; Donohue, Lindsay; Bowman-Dalley, Carrie; Breggman, Bejamin; Negro, Paulo; Gordon, Stephanie; Estrada, Christian (July 2024). "Efficacy of addition of the anti-inflammatory, IV glutathione to standard ketamine IV therapy in major depressive disorder". Psychiatry Research. 337 (115949). doi:10.1016/j.psychres.2024.115949.
↑Eshkevari, Ladan; Jasinski, D. (2005). Pharmacokinetics in Nurse Anesthesia. Philadelphia, PA: Churchill-Livingston.
↑Trout, Kimberly K.; Eshkevari, Ladan (2013). "Pain management in the parturient". In Varney, Helen (ed.). Varney's Midwifery. Burlington, MA: Jones and Bartlett Learning.
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