Levi Garraway | |
---|---|
Born | |
Spouse | Gisele |
Parent(s) | Annie Marie Watkins Garraway Michael Garraway (died 1999) |
Relatives | Levi Watkins (uncle) |
Academic background | |
Education | AB, biochemical sciences, Harvard College MD, PhD, Harvard Medical School |
Academic work | |
Institutions | Harvard University Roche Holding AG Eli Lilly and Company Foundation Medicine Dana–Farber Cancer Institute Broad Institute |
Levi A. Garraway (born in 1968) [1] is an American oncologist. His research team was among the first to adapt genomics technologies to enable scalable,high-throughput clinical approaches to cancer gene mutation profiling. As a result,he was inducted into the American Society for Clinical Investigation,American Association for Cancer Research,and National Academy of Medicine.
Garraway was born to parents Annie Marie Watkins Garraway and Michael Garraway [2] in Oakland,California. [3] His mother earned a Ph.D. in mathematics and became a department chair at AT&T Bell Labs. As well,his uncle Levi Watkins was the first African-American student admitted to and graduate from Vanderbilt University School of Medicine. [2] His father,an émigréfrom the Caribbean,was also a professor of plant biology at Ohio State University. [2] [4] While Garraway was in high school,he hung around the university lab and helped his father with experiments. [5]
Garraway received his A.B. in biochemical sciences from Harvard College and his medical degree and Ph.D. from Harvard Medical School. He then completed his internship and residency in internal medicine at the Massachusetts General Hospital and his fellowship training in medical oncology at the Dana–Farber Cancer Institute. [6] His choice to pursue a medical degree on top of his PhD was the result of his academic family,specifically his uncle. [7]
Upon completing his fellowship,Garraway became an associate member of the Broad Institute and an assistant professor in the Department of Medical Oncology at the Dana–Farber Cancer Institute. [5] At Broad Institute,Garraway's research involved the systematic characterization of critical and targetable mechanisms enacted by common genomic alterations in human tumors. His research team was among the first to adapt genomics technologies to enable scalable,high-throughput clinical approaches to cancer gene mutation profiling. [8] In 2007,Garraway and Matthew Meyerson published a paper detailing a method for large-panel testing of 238 DNA mutations. This led to the establishment of Foundation Medicine. [9] As a result of his discovery,Garraway was eleceted a member of the American Society for Clinical Investigation in 2009. [8]
During his tenure at the Broad Institute,Garraway also became the co-leader of the Cancer Genetics Program at Dana-Farber/Harvard Cancer Center and an associate professor at Dana–Farber Cancer Institute and Harvard Medical School. In 2012,Garraway was a recipient of the Paul Marks Prize for Cancer Research from the Memorial Sloan-Kettering Cancer Center as a "promising scientist under the age of 45 in recognition of his contributions to cancer research." [10] He also earned the 19th annual Herbert and Maxine Block Memorial Lectureship Award for Achievement in Cancer. [11]
On September 14,2016,Garraway was appointed the Senior Vice President of Global Oncology at Eli Lilly and Company,succeeding Richard Gaynor. [12] In October 2019,Garraway started his new leadership role as Roche Holding AG's Chief Medical Officer. [7] He was also elected to the American Association for Cancer Research for "visionary contributions to the establishment of genomics-driven precision cancer medicine by pioneering high-throughput adaptation of genomic technologies to profile human tumors to identify actionable cancer gene mutations,allowing for precise patient population stratification." [13]
During the COVID-19 pandemic,Garraway was elected a member of the National Academy of Medicine "for the discovery of genetic drivers of melanoma,prostate cancer,and other malignancies,the discovery of mechanisms of response and resistance to anticancer therapies in melanoma and other cancer types,pioneering platforms and approaches to cancer precision medicine,and incorporating precision medicine principles in therapeutic development." [14]
Garraway and his wife Gisele have two children together;a son and a daughter. [5] As of 2007 [update] ,his younger sister Isla is a urologist and surgeon at University of California,Los Angeles's Jonsson Comprehensive Cancer Center. [15]
James Lewis Abbruzzese is the Chief of the Duke Division of Medical Oncology and associate director for Clinical Research for the Duke Cancer Institute. Previously,Abbruzzese was Chairman of the Department of Gastrointestinal Medical Oncology at the University of Texas M. D. Anderson Cancer Center where he held the M. G. and Lillie A. Johnson Chair for Cancer Treatment and Research and the Annie Laurie Howard Research Distinguished Professorship. Abbruzzese is one of the world's leaders in the clinical study and treatment of pancreatic cancer.
Todd R. Golub is a professor of pediatrics at the Harvard Medical School,the Charles A. Dana Investigator in Human Cancer Genetics at the Dana–Farber Cancer Institute,and the Director and a founding member of the Broad Institute of MIT and Harvard. He is a world leader in applying genomic tools to cancer research,having made important discoveries in the molecular basis of childhood leukemia.
Alan D. D'Andrea is an American cancer researcher and the Fuller American Cancer Society Professor of Radiation Oncology at Harvard Medical School. D'Andrea's research at the Dana Farber Cancer Institute focuses on chromosome instability and cancer susceptibility. He is currently the director of the Center for DNA Damage and Repair and the director of the Susan F. Smith Center for Women's Cancer.
Kenneth Offit is an American cancer geneticist and oncologist. He is currently Chief of the Clinical Genetics Service and the Robert and Kate Niehaus Chair in Inherited Cancer Genomics at Memorial Sloan Kettering Cancer Center. Offit is also a member of the Program in Cancer Biology and Genetics at the Sloan-Kettering Institute,Professor of Medicine and Healthcare Policy and Research at Weill Cornell Medical College,and a member of both the Board of Scientific Counselors of the National Cancer Institute and the Evaluation of Genomic Applications in Practice and Prevention working group of the U.S. Centers for Disease Control.
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William G. Kaelin Jr. is an American Nobel laureate physician-scientist. He is a professor of medicine at Harvard University and the Dana–Farber Cancer Institute. His laboratory studies tumor suppressor proteins. In 2016,Kaelin received the Albert Lasker Award for Basic Medical Research and the AACR Princess Takamatsu Award. He also won the Nobel Prize in Physiology or Medicine in 2019 along with Peter J. Ratcliffe and Gregg L. Semenza.
David M. Livingston was the Deputy Director of the Dana-Farber/Harvard Cancer Center,Emil Frei Professor of Genetics and Medicine at Harvard Medical School,Chairman of the Executive Committee for Research at Dana–Farber Cancer Institute. Dr. Livingston joined the Harvard faculty in 1973. His research focused on breast and ovarian cancer.
Mary-Ellen Taplin,is a research oncologist at Dana Farber Cancer Institute and Brigham and Women's Hospital in Harvard's Longwood Medical and Academic Area.
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Ann Hart Partridge is an American medical oncologist. She is the founder and director of the Young and Strong Program for Young Women with Breast Cancer at the Susan F. Smith Center for Women's Cancers at the Dana–Farber Cancer Institute.
Catherine J. Wu is an American physician-scientist who studies oncology. She is a Professor of Medicine and Chief of Division of Stem Cell Transplantation and Cellular Therapies at the Dana–Farber Cancer Institute. Her research focuses on longitudinal studies of patients with chronic lymphocytic leukemia (CLL).
Scott Allen Armstrong is an American pediatric oncologist and cancer biologist focused on chromatin-based control of gene expression in cancer and therapeutic discovery. Armstrong and his team were the first to isolate rare leukemia stem cells in a mouse model of leukemia.
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Levi Garraway publications indexed by Google Scholar