1765 — First medical school, University of Pennsylvania Medical School, which made Penn the first educational institution to become a university in the United States, Philadelphia[9]
1766 — First organized hunting club in America, the Gloucester Fox Hunting Club near Philadelphia
1777 — First United States Capital, Philadelphia. Philadelphia, Pennsylvania was the first capital under the First Continental Congress from September 5, 1774 to October 24, 1774. Philadelphia, Pennsylvania was the first capital under the Articles of Confederation from March 1, 1781 to June 21, 1783[11][12]
1780 — First abolition law, while the state capital was in Philadelphia[13]
1946 — First large-scale, electronic, digital computer capable of being reprogrammed to solve a full range of computing problems, ENIAC, at The University of Pennsylvania, Philadelphia
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