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This is a list of singles which have reached number one on the Irish Singles Chart in 1978.
| Week ending | Song | Artist | Ref. |
|---|---|---|---|
| 7 January | "Mull of Kintyre" | Wings | |
| 14 January | |||
| 21 January | |||
| 28 January | |||
| 4 February | |||
| 11 February | |||
| 18 February | "Figaro" | Brotherhood of Man | |
| 25 February | "Take a Chance on Me" | ABBA | |
| 4 March | "The Rare Auld Times" | Danny Doyle | |
| 11 March | |||
| 18 March | "Wuthering Heights" | Kate Bush | |
| 25 March | |||
| 1 April | |||
| 8 April | "Matchstalk Men and Matchstalk Cats and Dogs" | Brian and Michael | |
| 15 April | |||
| 22 April | |||
| 29 April | "Night Fever" | The Bee Gees | |
| 6 May | |||
| 13 May | |||
| 20 May | "Rivers of Babylon" | Boney M | |
| 27 May | |||
| 3 June | |||
| 10 June | |||
| 17 June | |||
| 24 June | "You're the One That I Want" | John Travolta and Olivia Newton-John | |
| 1 July | |||
| 8 July | |||
| 15 July | [1] | ||
| 22 July | |||
| 29 July | |||
| 5 August | |||
| 12 August | |||
| 19 August | "Substitute" | Clout | |
| 26 August | "You're the One That I Want" | John Travolta and Olivia Newton-John | |
| 2 September | "Three Times a Lady" | Commodores | |
| 9 September | |||
| 16 September | |||
| 23 September | "Summer Night City" | ABBA | |
| 30 September | "One Day at a Time" | Gloria | |
| 7 October | "Summer Nights" | John Travolta and Olivia Newton-John | |
| 14 October | |||
| 21 October | |||
| 28 October | |||
| 4 November | "Sandy" | John Travolta | |
| 11 November | "One Day at a Time" | Gloria | |
| 18 November | "Hopelessly Devoted to You" | Olivia Newton-John | |
| 25 November | "Mary's Boy Child – Oh My Lord" | Boney M | |
| 2 December | |||
| 9 December | |||
| 16 December | |||
| 23 December | |||
| 30 December |