This is a list of the Spanish Singles number-ones of 1981. [1]
| Issue date | Song | Artist |
|---|---|---|
| 5 January | "Woman in Love" | Barbra Streisand |
| 12 January | ||
| 19 January | ||
| 26 January | "Perdóname" | Camilo Sesto |
| 2 February | "(Just Like) Starting Over" | John Lennon |
| 9 February | ||
| 16 February | "What's In A Kiss" | Gilbert O'Sullivan |
| 23 February | ||
| 2 March | ||
| 9 March | ||
| 16 March | "Qué Será" | Ana Belén |
| 23 March | "Another One Bites the Dust" | Queen |
| 30 March | "Johnny & Mary" | Robert Palmer |
| 6 April | ||
| 13 April | ||
| 20 April | ||
| 27 April | ||
| 4 May | "Everybody's Got to Learn Sometime" | The Korgis |
| 11 May | ||
| 18 May | ||
| 25 May | "Te Quiero Tanto" | Iván |
| 1 June | "Te Quiero" | José Luis Perales |
| 8 June | ||
| 15 June | "Stars On 45" | Stars On 45 |
| 22 June | ||
| 29 June | ||
| 6 July | ||
| 13 July | ||
| 20 July | ||
| 27 July | "Ay, Amor" | Víctor Manuel |
| 3 August | ||
| 10 August | "Enola Gay" | Orchestral Manoeuvres in the Dark |
| 17 August | ||
| 24 August | "De niña a Mujer" | Julio Iglesias |
| 31 August | ||
| 7 September | "Hands Up (Give Me Your Heart)" | Ottawan |
| 14 September | "El Baile de los Pajaritos" (Chicken Dance) | María Jesús y su Acordeón |
| 21 September | "Ma quale idea" | Pino D'Angiò |
| 28 September | ||
| 5 October | "Bette Davis Eyes" | Kim Carnes |
| 12 October | "Ma Quale Idea" | Pino D'Angiò |
| 19 October | ||
| 26 October | ||
| 2 November | ||
| 9 November | ||
| 16 November | ||
| 23 November | ||
| 30 November | ||
| 7 December | ||
| 14 December | ||
| 21 December | ||
| 28 December |