Lori West | |
---|---|
Born | United States |
Spouse(s) | Jeffrey Smallhorn |
Academic background | |
Education | BSc, University of Florida MD, 1983, Tulane University School of Medicine DPhil, 1995, Balliol College, Oxford |
Academic work | |
Institutions | University of Alberta University of Toronto |
Lori Jeanne West FRSC OC is an American-Canadian pediatric cardiologist. She holds the Tier 1 Canada Research Chair in Cardiac Transplantation at the University of Alberta.
West was born in the United States. [1] She completed her undergraduate degree at the University of Florida, [2] where she was initially most interested in field biology and ornithology. [3] Following this,West earned her medical degree at the Tulane University School of Medicine in 1983 [4] and completed her pediatric training at the University of California,Los Angeles. She also decided to train in pediatric cardiology and moved to Toronto to study at the Hospital for Sick Children. [5] As pediatric transplantation became more popular, [5] West chose to pursue her DPhil from Balliol College,Oxford in 1995. [4]
Upon returning to North America,West took over the transplant program at Toronto's Hospital for Sick Children in 1994. [6] While serving in this role,she pioneered the procedure to successfully transplant a heart from someone with one blood type into a baby with a different blood type. [7] West's first ABO-incompatible heart transplant was on a baby named Caleb with type o blood. She conducted the transplant on the theory that a newborn's immune system was so immature,it had not yet developed the antibodies to attack the foreign heart. [6]
West and her husband's tenure at Sick Kids ended in 2005 when they were recruited by Terry Klassen to join Alberta's Stollery Children's Hospital. [1] As a researcher in the University of Alberta (U of A) Faculty of Medicine and Dentistry,she was appointed the head of Canada's first national transplant research program. [8] Due to her overall research and transplant success,West was recognized by Alberta Venture as one of the province's 50 Most Influential People in 2014. [9] In the same year,West was also named to a three-year term on the Governing Council of the Canadian Institutes of Health Research. [10]
In 2017,West was elected a Fellow of the Royal Society of Canada for having "focused her career on finding treatments for infants with lethal cardiac malformations." [11] She was also re-appointed the Tier 1 Canada Research Chair in Cardiac Transplantation. [12] During the COVID-19 pandemic,West led a study to discover why people with different blood types react differently to the novel coronavirus. [13] Later in December,she was named an Officer of the Order of Canada for "her leadership in the field of organ transplantation and donation,notably for her breakthrough research in infant heart transplantation." [14]
West is married to Jeffrey Smallhorn,a fellow cardiologist. [1] In her free time,she enjoys playing the piano and horseback riding. [3]
Cardiology is a branch of medicine that deals with the disorders of the heart as well as some parts of the circulatory system. The field includes medical diagnosis and treatment of congenital heart defects,coronary artery disease,heart failure,valvular heart disease and electrophysiology. Physicians who specialize in this field of medicine are called cardiologists,a specialty of internal medicine. Pediatric cardiologists are pediatricians who specialize in cardiology. Physicians who specialize in cardiac surgery are called cardiothoracic surgeons or cardiac surgeons,a specialty of general surgery.
Helen Brooke Taussig was an American cardiologist,working in Baltimore and Boston,who founded the field of pediatric cardiology. She is credited with developing the concept for a procedure that would extend the lives of children born with Tetralogy of Fallot. This concept was applied in practice as a procedure known as the Blalock-Thomas-Taussig shunt. The procedure was developed by Alfred Blalock and Vivien Thomas,who were Taussig's colleagues at the Johns Hopkins Hospital.
The Toronto General Hospital (TGH) is a major teaching hospital in Toronto,Ontario,Canada and the flagship campus of University Health Network (UHN). It is located in the Discovery District of Downtown Toronto along University Avenue's Hospital Row;it is directly north of The Hospital for Sick Children,across Gerrard Street West,and east of Princess Margaret Cancer Centre and Mount Sinai Hospital. The hospital serves as a teaching hospital for the University of Toronto Faculty of Medicine. In 2021,Newsweek ranked TGH as the 4th best hospital in the world and 1st in Canada. In 2019,the hospital was ranked first for research in Canada by Research Infosource for the ninth consecutive year.
Boston Children's Hospital formerly known as Children's HospitalBoston until 2012 is a nationally ranked,freestanding acute care children's hospital located in Boston,Massachusetts,adjacent both to its teaching affiliate,Harvard Medical School,and to Dana-Farber Cancer Institute. Dana-Farber and Children's jointly operate the Dana-Farber/Boston Children's Cancer and Blood Disorders Center to deliver comprehensive care for all types of childhood cancers. The hospital is home to the largest hospital based pediatric research program in the world. The hospital features 404 pediatric beds and provides comprehensive pediatric specialties and subspecialties to infants,children,teens,and young adults aged 0–21 throughout Massachusetts,the United States,and the world. The hospital also sometimes treats adults that require pediatric care. The hospital uses the Brigham and Women's Hospital's rooftop helipad and is an ACS verified level I pediatric trauma center,1 of 3 in Boston. The hospital features a regional pediatric intensive-care unit and an American Academy of Pediatrics verified level IV neonatal intensive care unit. Boston Children's Hospital has been ranked as best pediatric medical center by U.S. News &World Report more times than any other hospital.
Children's National Hospital is a nationally ranked,freestanding,323-bed,pediatric acute care children's hospital located in Washington D.C.. It is affiliated with the George Washington University School of Medicine and the Howard University College of Medicine. The hospital provides comprehensive pediatric specialties and subspecialties to infants,children,teens,and young adults aged 0–21 throughout the region. The hospital features an ACS verified level I pediatric trauma center,the only in the District of Columbia. Its regional pediatric intensive-care unit and neonatal intensive care units serve the region. The hospital also has a rooftop helipad for critical pediatric transport.
Alberta Children's Hospital (ACH) is the largest public hospital for sick children in the prairie provinces,and is located in Calgary,Alberta,Canada. It is operated by Alberta Health Services –Calgary Health Region. The new facility opened on September 27,2006,and is the first free-standing pediatric facility to be built in Canada in more than 20 years. It was originally opened on May 19,1922,as the Junior Red Cross Children's Hospital. It is located west of the University of Calgary campus grounds and just across from the site of the Foothills Medical Centre.
Morgan Stanley Children's Hospital of NewYork-Presbyterian is a women's and children's hospital at 3959 Broadway,near West 165th Street,in the Washington Heights neighborhood of Manhattan,New York City. It is a part of NewYork-Presbyterian Hospital and the Columbia University Irving Medical Center. The hospital treats patients aged 0–21 from New York City and around the world. The hospital features a dedicated regional ACS designated pediatric Level 1 Trauma Center and is named after financial firm Morgan Stanley,which largely funded its construction through philanthropy.
The University of Alberta Hospital (UAH) is a research and teaching hospital in Edmonton,Alberta,Canada. The hospital is affiliated with the University of Alberta and run by Alberta Health Services,the health authority for Alberta. It is one of Canada's leading health sciences centres,providing a comprehensive range of diagnostic and treatment services to inpatients and outpatients. The UAH treats over 700,000 patients annually.
Atrial septostomy is a surgical procedure in which a small hole is created between the upper two chambers of the heart,the atria. This procedure is primarily used to palliate dextro-Transposition of the great arteries or d-TGA,a life-threatening cyanotic congenital heart defect seen in infants. It is performed prior to an arterial switch operation. Atrial septostomy has also seen limited use as a surgical treatment for pulmonary hypertension. The first atrial septostomy was developed by Vivien Thomas in a canine model and performed in humans by Alfred Blalock. The Rashkind balloon procedure,a common atrial septostomy technique,was developed in 1966 by American cardiologist William Rashkind at the Children's Hospital of Philadelphia.
The Stollery Children's Hospital is a 218 bed children's hospital that opened in October 2001. It is a "hospital within a hospital," being situated within the University of Alberta Hospital and co-located with Mazankowski Alberta Heart Institute in the Walter C. Mackenzie Health Sciences Centre in Edmonton,Alberta,Canada.
Adrian Kantrowitz was an American cardiac surgeon whose team performed the world's second heart transplant attempt at Maimonides Medical Center in Brooklyn,New York on December 6,1967. The infant lived for only six hours. At a press conference afterwards,Kantrowitz emphasized that he considered the operation to have been a failure.
Charles D Fraser,Jr. is the medical director and surgeon of the Texas Center for Pediatric and Congenital Heart Disease at Dell Children's Medical Center. Formerly,Fraser was chief of congenital heart surgery and cardiac surgeon-in-charge at Texas Children's Hospital,the nation's largest pediatric hospital,served as chief of the Congenital Heart Surgery Division at Baylor College of Medicine,and director of the Adult Congenital Heart Surgery Program at the Texas Heart Institute.
ABO-incompatible (ABOi) transplantation is a method of allocation in organ transplantation that permits more efficient use of available organs regardless of ABO blood type,which would otherwise be unavailable due to hyperacute rejection. Primarily in use in infants and young toddlers,research is ongoing to allow for increased use of this capability in adult transplants. Normal ABO-compatibility rules may be observed for all recipients. This means that anyone may receive a transplant of a type-O organ,and consequently,type-O recipients are one of the biggest beneficiaries of ABO-incompatible transplants. While focus has been on infant heart transplants,the principles generally apply to other forms of solid organ transplantation.
James K. Kirklin is an American cardiac surgeon who has made significant scientific and surgical contributions in the fields of heart transplantation and mechanical circulatory support devices to assist the pumping action of the heart. He is Professor of Surgery,former Director of the Division of Cardiothoracic Surgery (2006-2016),Director of the James and John Kirklin Institute for Research in Surgical Outcomes (2016–present),former Co-Director of the University of Alabama at Birmingham (UAB) Comprehensive Cardiovascular Center and holds the James Kirklin Chair of Cardiovascular Surgery at UAB.
Jane Somerville is a British emeritus professor of cardiology,Imperial College,who is best known for defining the concept and subspecialty of grown ups with congenital heart disease (GUCH) and being chosen as the physician involved with Britain's first heart transplantation in 1968.
Catherine Annie Neill was a British pediatric cardiologist who spent the majority of her career at the Johns Hopkins Children's Center in Baltimore,where she worked alongside Helen B. Taussig. Her primary interest was congenital heart defects;she discovered one type of defect,scimitar syndrome,in 1960.
Willis John Potts was an American pediatric surgeon and one of the earliest physicians to focus on the surgical treatment of heart problems in children. Potts set up one of the country's first pediatric surgery programs at Children's Memorial Hospital in Chicago.
Lisa Robinson is a clinician-scientist. She is a University of Toronto professor in the Department of Paediatrics and the Vice Dean Strategy and Operations at the Faculty of Medicine,former Head of the Division of Nephrology at The Hospital for Sick Children,a Senior Scientist at the SickKids Research Institute,and the first-ever Chief Diversity officer for the Faculty of Medicine at University of Toronto.
Leonard Lee Bailey (1942–2019) was an American surgeon who garnered international media attention in 1984 for transplanting a baboon’s heart into a human infant.
Rosemary Radley-Smith was a British paediatric cardiologist who worked at Harefield Hospital,West London for many years and founded several charities. In 2001,she received the Pride of Britain Award.