 | This article relies largely or entirely on a single source .(June 2025) |
| Los Premios 40 Principales 2010 | |
|---|---|
| Date | December 10, 2010 |
| Venue | Palacio de Deportes de la Comunidad de Madrid [1] |
| Host | Mar Montoro, Frank Blanco and Tony Aguilar |
| Network | Cuatro (Spain) A&E Network (Latin America) |
| Artist(s) | Song(s) |
|---|---|
| Kylie Minogue | "Get Outta My Way" "In My Arms" "All the Lovers" |
| Edward Maya Vika Jigulina | "Stereo Love" |
| Maldita Nerea | "El secreto de las tortugas" "Tu mirada me hace grande" |
| Melendi | "Barbie de extrarradio" |
| Ricky Martin | "Lo mejor de mi vida eres tú" |
| Nena Daconte | "No te invité a dormir" |
| Inna | "Hot" "Déjà Vu" |
| Dani Martín | "16 añitos" |
| Oceana | "Cry Cry" |
| Robert Ramírez | "Sick of Love" |
| Juanes | "Yerbatero" "Y No Regresas" |
| 40 El Musical cast | "I Gotta Feeling" |
| Macaco Estopa | "Con la mano levantá" |
| Alejandro Sanz | "Lola Soledad" "Desde Cuándo" (with Juanes and Dani Martín) "Looking for Paradise" |
| Kesha | "Tik Tok" "We R Who We R" |