Lurosetron

Last updated
Lurosetron
Lurosetron.png
Clinical data
ATC code
  • none
Identifiers
  • 6-fluoro-5-methyl-2-[(5-methyl-1H-imidazol-4-yl)methyl]-2,3,4,5-tetrahydro-1H-pyrido[4,3-b]indol-1-one
CAS Number
PubChem CID
ChemSpider
UNII
KEGG
CompTox Dashboard (EPA)
Chemical and physical data
Formula C17H17FN4O
Molar mass 312.348 g·mol−1
3D model (JSmol)
  • CC1=C(N=CN1)CN2CCC3=C(C2=O)C4=C(N3C)C(=CC=C4)F
  • InChI=1S/C17H17FN4O/c1-10-13(20-9-19-10)8-22-7-6-14-15(17(22)23)11-4-3-5-12(18)16(11)21(14)2/h3-5,9H,6-8H2,1-2H3,(H,19,20) X mark.svgN
  • Key:NUMKWGDDRWJQMY-UHFFFAOYSA-N X mark.svgN
 X mark.svgNYes check.svgY  (what is this?)    (verify)

Lurosetron (INN) is a serotonin 5-HT3 receptor antagonist. [1]

Synthesis

Lurosetron synthesis Lurosetron synthesis.svg
Lurosetron synthesis

References

  1. Prakash SP, Cable KM, Correa ID, Fellows L, Montgomery S, Newman JJ, Waterhouse L, Wells GN, Sutherland DR (1995). "Synthesis of isotopically labelled pyridoindolone 5-HT3 receptor antagonists". Journal of Labelled Compounds and Radiopharmaceuticals. 36 (10): 993–1007. doi:10.1002/jlcr.2580361011.
  2. EP 0353983,Coates, Ian Harold; Oxford, Alexander William& North, Peter Charleset al.,published 1990-02-07, assigned to Glaxo Group Ltd.