MATR3 | |||||||||||||||||||||||||||||||||||||||||||||||||||
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Identifiers | |||||||||||||||||||||||||||||||||||||||||||||||||||
Aliases | MATR3 , ALS21, MPD2, VCPDM, matrin 3 | ||||||||||||||||||||||||||||||||||||||||||||||||||
External IDs | OMIM: 164015 MGI: 1298379 HomoloGene: 7830 GeneCards: MATR3 | ||||||||||||||||||||||||||||||||||||||||||||||||||
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Wikidata | |||||||||||||||||||||||||||||||||||||||||||||||||||
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Matrin-3 is a protein that in humans is encoded by the MATR3 gene. [3] [4]
The protein encoded by this gene is localized in the nuclear matrix. It may play a role in transcription or may interact with other nuclear matrix proteins to form the internal fibrogranular network. Two transcript variants encoding the same protein have been identified for this gene. [4]
Mutations in the Matrin 3 gene are associated with familial amyotrophic lateral sclerosis. [5]
E3 SUMO-protein ligase PIAS4 is one of several protein inhibitor of activated STAT (PIAS) proteins. It is also known as protein inhibitor of activated STAT protein gamma, and is an enzyme that in humans is encoded by the PIAS4 gene.
Tyrosine-protein phosphatase non-receptor type 2 is an enzyme that in humans is encoded by the PTPN2 gene.
Pinin is a protein that in humans is encoded by the PNN gene.
Large proline-rich protein BAT3 is a protein that in humans is encoded by the BAT3 gene.
Ras GTPase-activating protein-binding protein 1 is an enzyme that in humans is encoded by the G3BP1 gene.
Pre-mRNA-processing factor 40 homolog A is a protein that in humans is encoded by the PRPF40A gene.
Transcription elongation regulator 1, also known as TCERG1, is a protein which in humans is encoded by the TCERG1 gene.
Pre-mRNA-processing factor 19 is a protein that in humans is encoded by the PRPF19 gene.
60S ribosomal protein L4 is a protein that in humans is encoded by the RPL4 gene.
U2 small nuclear ribonucleoprotein B is a protein that in humans is encoded by the SNRPB2 gene.
Serine/threonine-protein kinase PRP4 homolog is an enzyme that in humans is encoded by the PRPF4B gene.
Eukaryotic initiation factor 4A-III is a protein that in humans is encoded by the EIF4A3 gene.
THO complex subunit 1 is a protein that in humans is encoded by the THOC1 gene.
60S ribosomal protein L8 is a protein that in humans is encoded by the RPL8 gene.
Leucine-rich PPR motif-containing protein, mitochondrial is a protein that in humans is encoded by the LRPPRC gene. Transcripts ranging in size from 4.8 to 7.0 kb which result from alternative polyadenylation have been reported for this gene.
Nucleoporin 160 (Nup160) is a protein that in humans is encoded by the NUP160 gene.
Zinc finger protein 638 is a protein that in humans is encoded by the ZNF638 gene.
Eukaryotic translation initiation factor 5B is a protein that in humans is encoded by the EIF5B gene.
Heterogeneous nuclear ribonucleoprotein D-like, also known as HNRPDL, is a protein which in humans is encoded by the HNRPDL gene.
ESF1 homolog is a protein that in humans is encoded by the ESF1 gene.