MLSTD2

FAR1
Identifiers
Aliases	FAR1 , MLSTD2, SDR10E1, PFCRD, fatty acyl-CoA reductase 1, CSPSD
External IDs	OMIM: 616107 MGI: 1914670 HomoloGene: 41718 GeneCards: FAR1
Gene location (Human) Chr. Chromosome 11 (human) [1] Band 11p15.3 Start 13,668,668 bp [1] End 13,732,346 bp [1]
Gene location (Mouse) Chr. Chromosome 7 (mouse) [2] Band 7|7 F1 Start 113,113,041 bp [2] End 113,170,718 bp [2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in corpus callosum jejunal mucosa oral cavity monocyte spinal cord rectum bone marrow cells subthalamic nucleus inferior ganglion of vagus nerve pylorus Top expressed in epithelium of stomach pyloric antrum substantia nigra mammillary body proximal tubule mucous cell of stomach cumulus cell left colon seminal vesicula lateral geniculate nucleus More reference expression data BioGPS n/a
Gene ontology Molecular function fatty-acyl-CoA reductase (alcohol-forming) activity oxidoreductase activity alcohol-forming fatty acyl-CoA reductase activity Cellular component integral component of membrane peroxisomal membrane peroxisome peroxisomal matrix membrane integral component of peroxisomal membrane Biological process glycerophospholipid biosynthetic process long-chain fatty-acyl-CoA metabolic process lipid metabolism ether lipid biosynthetic process wax biosynthetic process Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 84188 67420 Ensembl ENSG00000197601 ENSMUSG00000030759 UniProt Q8WVX9 Q922J9 RefSeq (mRNA) NM_032228 NM_001285831 NM_026143 NM_027379 NM_001360668 NM_001360669 RefSeq (protein) NP_115604 NP_001272760 NP_081655 NP_001347597 NP_001347598 Location (UCSC) Chr 11: 13.67 – 13.73 Mb Chr 7: 113.11 – 113.17 Mb PubMed search [3] [4]
Wikidata
View/Edit Human View/Edit Mouse

Fatty acyl-CoA reductase 1 is an enzyme that in humans is encoded by the FAR1 gene. ^{[5] [6] [7] [8]}

References

1. GRCh38: Ensembl release 89: ENSG00000197601 - Ensembl, May 2017
2. GRCm38: Ensembl release 89: ENSMUSG00000030759 - Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. Cheng JB, Russell DW (Aug 2004). "Mammalian wax biosynthesis. I. Identification of two fatty acyl-Coenzyme A reductases with different substrate specificities and tissue distributions". J Biol Chem. 279 (36): 37789–97. doi: 10.1074/jbc.M406225200 . PMC   2757098 . PMID   15220348.
6. Cheng JB, Russell DW (Aug 2004). "Mammalian wax biosynthesis. II. Expression cloning of wax synthase cDNAs encoding a member of the acyltransferase enzyme family". J Biol Chem. 279 (36): 37798–807. doi: 10.1074/jbc.M406226200 . PMC   2743083 . PMID   15220349.
7. Persson B, Kallberg Y, Bray JE, Bruford E, Dellaporta SL, Favia AD, Duarte RG, Jornvall H, Kavanagh KL, Kedishvili N, Kisiela M, Maser E, Mindnich R, Orchard S, Penning TM, Thornton JM, Adamski J, Oppermann U (Feb 2009). "The SDR (short-chain dehydrogenase/reductase and related enzymes) nomenclature initiative". Chem Biol Interact. 178 (1–3): 94–8. Bibcode:2009CBI...178...94P. doi:10.1016/j.cbi.2008.10.040. PMC   2896744 . PMID   19027726.
8. "Entrez Gene: MLSTD2 male sterility domain containing 2".

Further reading

• Ewing RM, Chu P, Elisma F, et al. (2007). "Large-scale mapping of human protein-protein interactions by mass spectrometry". Mol. Syst. Biol. 3 (1): 89. doi:10.1038/msb4100134. PMC   1847948 . PMID   17353931.
• Foster LJ, Rudich A, Talior I, et al. (2006). "Insulin-dependent interactions of proteins with GLUT4 revealed through stable isotope labeling by amino acids in cell culture (SILAC)". J. Proteome Res. 5 (1): 64–75. doi:10.1021/pr0502626. PMID   16396496.
• Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC   528928 . PMID   15489334.
• Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi: 10.1038/ng1285 . PMID   14702039.
• Clark HF, Gurney AL, Abaya E, et al. (2003). "The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment". Genome Res. 13 (10): 2265–70. doi:10.1101/gr.1293003. PMC   403697 . PMID   12975309.
• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi: 10.1073/pnas.242603899 . PMC   139241 . PMID   12477932.