MT1M

MT1M
Identifiers
Aliases	MT1M , MT-1M, MT-IM, MT1, MT1K, metallothionein 1M
External IDs	OMIM: 156357; GeneCards: MT1M; OMA:MT1M - orthologs
Gene location (Human) Chr. Chromosome 16 (human) [1] Band 16q13 Start 56,632,659 bp [1] End 56,633,981 bp [1]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in mucosa of transverse colon left uterine tube pericardium right lobe of liver external globus pallidus gastric mucosa synovial joint left coronary artery amygdala tibial arteries n/a More reference expression data BioGPS More reference expression data
Gene ontology Molecular function zinc ion binding metal ion binding Cellular component cytoplasm perinuclear region of cytoplasm nucleus Biological process negative regulation of growth cellular response to zinc ion cellular zinc ion homeostasis detoxification of copper ion cellular response to cadmium ion cellular response to copper ion Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 4499 n/a Ensembl ENSG00000205364 n/a UniProt Q8N339 n/a RefSeq (mRNA) NM_176870 n/a RefSeq (protein) NP_789846 n/a Location (UCSC) Chr 16: 56.63 – 56.63 Mb n/a PubMed search [2] n/a
Wikidata
View/Edit Human

Metallothionein-1M is a protein that in humans is encoded by the MT1M gene. ^{[3] [4] [5]}

References

1. GRCh38: Ensembl release 89: ENSG00000205364 – Ensembl, May 2017
2. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
3. West AK, Stallings R, Hildebrand CE, Chiu R, Karin M, Richards RI (Mar 1991). "Human metallothionein genes: structure of the functional locus at 16q13". Genomics. 8 (3): 513–8. doi:10.1016/0888-7543(90)90038-V. PMID   2286373.
4. Stennard FA, Holloway AF, Hamilton J, West AK (Sep 1994). "Characterisation of six additional human metallothionein genes". Biochim Biophys Acta. 1218 (3): 357–65. doi:10.1016/0167-4781(94)90189-9. PMID   8049263.
5. "Entrez Gene: MT1M metallothionein 1M".

Further reading

• Lederer CW, Torrisi A, Pantelidou M, et al. (2007). "Pathways and genes differentially expressed in the motor cortex of patients with sporadic amyotrophic lateral sclerosis". BMC Genomics. 8: 26. doi: 10.1186/1471-2164-8-26 . PMC   1796866 . PMID   17244347.
• Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC   528928 . PMID   15489334.
• Izmailova E, Bertley FM, Huang Q, et al. (2003). "HIV-1 Tat reprograms immature dendritic cells to express chemoattractants for activated T cells and macrophages". Nat. Med. 9 (2): 191–7. doi:10.1038/nm822. PMID   12539042. S2CID   26145639.
• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi: 10.1073/pnas.242603899 . PMC   139241 . PMID   12477932.
• Vandeghinste N, Proost P, De Ley M (2000). "Metallothionein isoform gene expression in zinc-treated human peripheral blood lymphocytes". Cell. Mol. Biol. (Noisy-le-grand). 46 (2): 419–33. PMID   10774930.
• Hellemans G, Soumillion A, Proost P, et al. (2000). "Metallothioneins in human kidneys and associated tumors". Nephron. 83 (4): 331–40. doi:10.1159/000045425. PMID   10575295. S2CID   26103380.