MTG1

MTG1
Identifiers
Aliases	MTG1 , GTP, GTPBP7, mitochondrial ribosome associated GTPase 1
External IDs	MGI: 2685015 HomoloGene: 44527 GeneCards: MTG1
Gene location (Human)
Chr.	Chromosome 10 (human)
End	133,422,520 bp
Gene location (Mouse)
Chr.	Chromosome 7 (mouse)
End	139,730,699 bp
RNA expression pattern
	Top expressed in
	right lobe of liver; ; right adrenal gland; ; pancreatic ductal cell; ; left adrenal gland; ; right lobe of thyroid gland; ; cerebellar hemisphere; ; body of pancreas; ; sural nerve; ; left lobe of thyroid gland; ; spleen;
	Top expressed in
	interventricular septum; ; masseter muscle; ; proximal tubule; ; skeletal muscle tissue; ; brown adipose tissue; ; quadriceps femoris muscle; ; morula; ; tibialis anterior muscle; ; lens; ; right ventricle;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	nucleotide binding ; GTP binding ; GTPase activity ;
Cellular component	mitochondrial inner membrane ; mitochondrial matrix ; mitochondrial ribosome ; mitochondrion ; membrane ;
Biological process	regulation of respiratory system process ; regulation of mitochondrial translation ; regulation of translation ; ribosome biogenesis ;
	Sources:Amigo / QuickGO
Orthologs
	92170
	212508
	ENSG00000148824
	ENSMUSG00000039018
	Q9BT17
	Q8R2R6
	NM_138384
	NM_199301
	NP_612393
	NP_955005
	Wikidata
View/Edit Human	View/Edit Mouse

Last updated January 12, 2024

Mitochondrial GTPase 1 is an enzyme that in humans is encoded by the MTG1 gene.^[5]^[6]

Related Research Articles

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References

1 2 3 GRCh38: Ensembl release 89: ENSG00000148824 - Ensembl, May 2017
1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000039018 - Ensembl, May 2017
↑ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ Barrientos A, Korr D, Barwell KJ, Sjulsen C, Gajewski CD, Manfredi G, Ackerman S, Tzagoloff A (Jun 2003). "MTG1 codes for a conserved protein required for mitochondrial translation". Mol Biol Cell. 14 (6): 2292–302. doi:10.1091/mbc.E02-10-0636. PMC 194879 . PMID 12808030.
↑ "Entrez Gene: MTG1 mitochondrial GTPase 1 homolog (S. cerevisiae)".

Horisberger MA (1992). "Interferon-induced human protein MxA is a GTPase which binds transiently to cellular proteins". J. Virol. 66 (8): 4705–9. doi:10.1128/JVI.66.8.4705-4709.1992. PMC 241296 . PMID 1629950.
Wilson AL, Sheridan KM, Erdman RA, Maltese WA (1996). "Prenylation of a Rab1B mutant with altered GTPase activity is impaired in cell-free systems but not in intact mammalian cells". Biochem. J. 318 (3): 1007–14. doi:10.1042/bj3181007. PMC 1217717 . PMID 8836150.
Tsai SC, Adamik R, Hong JX, et al. (1998). "Effects of arfaptin 1 on guanine nucleotide-dependent activation of phospholipase D and cholera toxin by ADP-ribosylation factor". J. Biol. Chem. 273 (33): 20697–701. doi: 10.1074/jbc.273.33.20697 . PMID 9694811.
Opdam FJ, Echard A, Croes HJ, et al. (2000). "The small GTPase Rab6B, a novel Rab6 subfamily member, is cell-type specifically expressed and localised to the Golgi apparatus". J. Cell Sci. 113 (15): 2725–35. doi:10.1242/jcs.113.15.2725. PMID 10893188.
Gao X, Satoh T, Liao Y, et al. (2001). "Identification and characterization of RA-GEF-2, a Rap guanine nucleotide exchange factor that serves as a downstream target of M-Ras". J. Biol. Chem. 276 (45): 42219–25. doi: 10.1074/jbc.M105760200 . PMID 11524421.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi: 10.1073/pnas.242603899 . PMC 139241 . PMID 12477932.
Kuiperij HB, de Rooij J, Rehmann H, et al. (2003). "Characterisation of PDZ-GEFs, a family of guanine nucleotide exchange factors specific for Rap1 and Rap2". Biochim. Biophys. Acta. 1593 (2–3): 141–9. doi:10.1016/S0167-4889(02)00365-8. PMID 12581858.
Premzl M, Sangiorgio L, Strumbo B, et al. (2003). "Shadoo, a new protein highly conserved from fish to mammals and with similarity to prion protein". Gene. 314: 89–102. doi:10.1016/S0378-1119(03)00707-8. PMID 14527721.
Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi: 10.1038/ng1285 . PMID 14702039.
Deloukas P, Earthrowl ME, Grafham DV, et al. (2004). "The DNA sequence and comparative analysis of human chromosome 10". Nature. 429 (6990): 375–81. Bibcode:2004Natur.429..375D. doi: 10.1038/nature02462 . PMID 15164054.
Premzl M, Gready JE, Jermiin LS, et al. (2005). "Evolution of vertebrate genes related to prion and Shadoo proteins--clues from comparative genomic analysis". Mol. Biol. Evol. 21 (12): 2210–31. CiteSeerX 10.1.1.327.5021 . doi: 10.1093/molbev/msh245 . PMID 15342797.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928 . PMID 15489334.
Kimura K, Wakamatsu A, Suzuki Y, et al. (2006). "Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes". Genome Res. 16 (1): 55–65. doi:10.1101/gr.4039406. PMC 1356129 . PMID 16344560.

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[refGRCh38Ensembl-1] 1 2 3 GRCh38: Ensembl release 89: ENSG00000148824 - Ensembl, May 2017

[refGRCm38Ensembl-2] 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000039018 - Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid12808030-5] Barrientos A, Korr D, Barwell KJ, Sjulsen C, Gajewski CD, Manfredi G, Ackerman S, Tzagoloff A (Jun 2003). "MTG1 codes for a conserved protein required for mitochondrial translation". Mol Biol Cell. 14 (6): 2292–302. doi:10.1091/mbc.E02-10-0636. PMC 194879 . PMID 12808030.

[entrez-6] "Entrez Gene: MTG1 mitochondrial GTPase 1 homolog (S. cerevisiae)".

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MTG1

Related Research Articles

References

Further reading