MUCL1

MUCL1
Identifiers
Aliases	MUCL1 , SBEM, mucin like 1
External IDs	OMIM: 610857 HomoloGene: 130916 GeneCards: MUCL1
Gene location (Human)
Chr.	Chromosome 12 (human)
End	54,896,008 bp
RNA expression pattern
	Top expressed in
	parotid gland; ; lactiferous duct; ; nipple; ; skin of abdomen; ; vulva; ; bronchial epithelial cell; ; trachea; ; right uterine tube; ; minor salivary gland; ; cingulate gyrus;
	n/a
	More reference expression data
	n/a
Orthologs
	118430
	n/a
	ENSG00000172551
	n/a
	Q96DR8
	n/a
	NM_058173
	n/a
	NP_477521
	n/a
	Wikidata
View/Edit Human

Last updated August 15, 2023

Mucin-like protein 1 is a protein that in humans is encoded by the MUCL1 gene.^[3]^[4]

Related Research Articles

Sialomucin core protein 24 also known as endolyn or CD164 is a protein that in humans is encoded by the CD164 gene. CD164 functions as a cell adhesion molecule.

Kallikrein-10 is a protein that in humans is encoded by the KLK10 gene.

Decoy receptor 2 (DCR2), also known as TRAIL receptor 4 (TRAILR4) and tumor necrosis factor receptor superfamily member 10D (TNFRSF10D), is a human cell surface receptor of the TNF-receptor superfamily.

Matrix metalloproteinase-26 also known as matrilysin-2 and endometase is an enzyme that in humans is encoded by the MMP26 gene.

Chimerin 2 (beta-chimaerin) is a protein that in humans is encoded by the CHN2 gene.

Prolactin-inducible protein also known as gross cystic disease fluid protein 15 (GCDFP-15), extra-parotid glycoprotein (EP-GP), gp17seminal actin-binding protein (SABP) or BRST2 is a protein that in humans is encoded by the PIP gene. It is upregulated by prolactin and androgens and downregulated by estrogen.

Oviduct-specific glycoprotein also known as oviductal glycoprotein(OGP) or estrogen-dependent oviduct protein, oviductin or mucin-9 is a protein that in humans is encoded by the OVGP1 gene.

Receptor-type tyrosine-protein phosphatase gamma is an enzyme that in humans is encoded by the PTPRG gene.

Tetraspanin-13 is a protein that in humans is encoded by the TSPAN13 gene.

Interleukin-17 receptor B is a protein that in humans is encoded by the IL17RB gene.

Epithelial membrane protein 1 is a protein that in humans is encoded by the EMP1 gene.

ETS homologous factor is a protein that in humans is encoded by the EHF gene. This gene encodes a protein that belongs to an ETS transcription factor subfamily characterized by epithelial-specific expression (ESEs). The encoded protein acts as a transcriptional repressor and may be associated with asthma susceptibility. This protein may be involved in epithelial differentiation and carcinogenesis.

Mesoderm development LRP chaperone, or MESD, is a protein that in humans is encoded by the MESD gene.

Transmembrane protease, serine 6 is an enzyme that in humans is encoded by the TMPRSS6 gene.

Mucin-20 is a protein that in humans is encoded by the MUC20 gene.

Alpha-protein kinase 1 is an enzyme that in humans is encoded by the ALPK1 gene.

Protein SOGA1 also known as SOGA family member 1 or suppressor of glucose, autophagy-associated protein 1 (SOGA1) is a protein that in humans is encoded by the SOGA1 gene.

Acidic leucine-rich nuclear phosphoprotein 32 family member D is a protein that in humans is encoded by the ANP32D gene.

A disintegrin and metalloproteinase with thrombospondin motifs 12 is an enzyme that in humans is encoded by the ADAMTS12 gene.

JAML or Junctional Adhesion Molecule-Like, or AMICA1 is a JAM transmembrane protein family member. It is composed of two extracellular immunoglobulin-like domains, a membrane-spanning region, and a cytoplasmic tail involved in activation signaling. A known ligand of JAML is Coxsackie virus and Adenovirus Receptor which has been shown to localize to the tight junctions of epithelial cells.

References

1 2 3 GRCh38: Ensembl release 89: ENSG00000172551 - Ensembl, May 2017
↑ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ Miksicek RJ, Myal Y, Watson PH, Walker C, Murphy LC, Leygue E (May 2002). "Identification of a novel breast- and salivary gland-specific, mucin-like gene strongly expressed in normal and tumor human mammary epithelium". Cancer Res. 62 (10): 2736–40. PMID 12019145.
↑ "Entrez Gene: SBEM small breast epithelial mucin".

Dias Neto E, Correa RG, Verjovski-Almeida S, et al. (2000). "Shotgun sequencing of the human transcriptome with ORF expressed sequence tags". Proc. Natl. Acad. Sci. U.S.A. 97 (7): 3491–6. Bibcode:2000PNAS...97.3491D. doi: 10.1073/pnas.97.7.3491 . PMC 16267 . PMID 10737800.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi: 10.1073/pnas.242603899 . PMC 139241 . PMID 12477932.
Clark HF, Gurney AL, Abaya E, et al. (2003). "The Secreted Protein Discovery Initiative (SPDI), a Large-Scale Effort to Identify Novel Human Secreted and Transmembrane Proteins: A Bioinformatics Assessment". Genome Res. 13 (10): 2265–70. doi:10.1101/gr.1293003. PMC 403697 . PMID 12975309.
Koga T, Horio Y, Mitsudomi T, et al. (2004). "Identification of MGB1 as a Marker in the Differential Diagnosis of Lung Tumors in Patients with a History of Breast Cancer by Analysis of Publicly Available SAGE Data". The Journal of Molecular Diagnostics. 6 (2): 90–5. doi:10.1016/S1525-1578(10)60495-3. PMC 1867472 . PMID 15096563.
Zhang Z, Henzel WJ (2005). "Signal peptide prediction based on analysis of experimentally verified cleavage sites". Protein Sci. 13 (10): 2819–24. doi:10.1110/ps.04682504. PMC 2286551 . PMID 15340161.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928 . PMID 15489334.
Hubé F, Mutawe M, Leygue E, Myal Y (2005). "Human small breast epithelial mucin: the promise of a new breast tumor biomarker". DNA Cell Biol. 23 (12): 842–9. doi:10.1089/dna.2004.23.842. PMID 15684711.
Wadle A, Mischo A, Imig J, et al. (2005). "Serological identification of breast cancer-related antigens from a Saccharomyces cerevisiae surface display library". Int. J. Cancer. 117 (1): 104–13. doi: 10.1002/ijc.21147 . PMID 15880534. S2CID 23079235.
Hubé F, Chooniedass-Kothari S, Hamedani MK, et al. (2006). "Identification of an octamer-binding site controlling the activity of the small breast epithelial mucin gene promoter". Front. Biosci. 11: 2483–95. doi: 10.2741/1984 . PMID 16720387.

This article on a gene on human chromosome 12 is a stub. You can help Wikipedia by expanding it.

This page is based on this Wikipedia article
Text is available under the CC BY-SA 4.0 license; additional terms may apply.
Images, videos and audio are available under their respective licenses.

[refGRCh38Ensembl-1] 1 2 3 GRCh38: Ensembl release 89: ENSG00000172551 - Ensembl, May 2017

[2] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid12019145-3] Miksicek RJ, Myal Y, Watson PH, Walker C, Murphy LC, Leygue E (May 2002). "Identification of a novel breast- and salivary gland-specific, mucin-like gene strongly expressed in normal and tumor human mammary epithelium". Cancer Res. 62 (10): 2736–40. PMID 12019145.

[entrez-4] "Entrez Gene: SBEM small breast epithelial mucin".

[1]

[2]

[3]

[4]

MUCL1

Related Research Articles

References

Further reading