MZB1

Last updated
MZB1
Identifiers
Aliases MZB1 , MEDA-7, PACAP, pERp1, marginal zone B and B1 cell specific protein
External IDs MGI: 1917066 HomoloGene: 12333 GeneCards: MZB1
Gene location (Human)
Ideogram human chromosome 5.svg
Chr. Chromosome 5 (human) [1]
Human chromosome 5 ideogram.svg
HSR 1996 II 3.5e.svg
Red rectangle 2x18.png
Band 5q31.2Start139,387,480 bp [1]
End139,390,081 bp [1]
Orthologs
SpeciesHumanMouse
Entrez

51237

69816

Ensembl

ENSG00000170476

ENSMUSG00000024353

UniProt

Q8WU39

Q9D8I1

RefSeq (mRNA)

NM_016459

NM_027222

RefSeq (protein)

NP_057543

NP_081498

Location (UCSC) Chr 5: 139.39 – 139.39 Mb Chr 18: 35.65 – 35.65 Mb
PubMed search [3] [4]
Wikidata
View/Edit Human View/Edit Mouse

Marginal zone B and B1 cell-specific protein is a protein that in humans is encoded by the MZB1 gene. [5]

Protein biological molecule consisting of chains of amino acid residues

Proteins are large biomolecules, or macromolecules, consisting of one or more long chains of amino acid residues. Proteins perform a vast array of functions within organisms, including catalysing metabolic reactions, DNA replication, responding to stimuli, providing structure to cells and organisms, and transporting molecules from one location to another. Proteins differ from one another primarily in their sequence of amino acids, which is dictated by the nucleotide sequence of their genes, and which usually results in protein folding into a specific three-dimensional structure that determines its activity.

Gene Basic physical and functional unit of heredity

In biology, a gene is a sequence of nucleotides in DNA or RNA that codes for a molecule that has a function. During gene expression, the DNA is first copied into RNA. The RNA can be directly functional or be the intermediate template for a protein that performs a function. The transmission of genes to an organism's offspring is the basis of the inheritance of phenotypic trait. These genes make up different DNA sequences called genotypes. Genotypes along with environmental and developmental factors determine what the phenotypes will be. Most biological traits are under the influence of polygenes as well as gene–environment interactions. Some genetic traits are instantly visible, such as eye color or number of limbs, and some are not, such as blood type, risk for specific diseases, or the thousands of basic biochemical processes that constitute life.

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References

  1. 1 2 3 GRCh38: Ensembl release 89: ENSG00000170476 - Ensembl, May 2017
  2. 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000024353 - Ensembl, May 2017
  3. ↑ "Human PubMed Reference:".
  4. ↑ "Mouse PubMed Reference:".
  5. ↑ "Entrez Gene: Marginal zone B and B1 cell-specific protein".

Further reading

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