Mario Gaudino

Last updated
Mario F.L. Gaudino
CitizenshipItaly
Education
Occupation(s)Cardiovascular surgeon, researcher, educator
Medical career
ProfessionSurgeon
InstitutionsWeill Cornell Medicine
Researchcoronary bypass grafting, aortic surgery, atrial fibrillation
Website https://weillcornell.org/mariogaudino

Mario F.L. Gaudino, MD, PhD, MSCE, FEBCTS, FACC, FAHA is an Italian cardiothoracic surgeon who is the Stephen and Suzanne Weiss Professor in Cardiothoracic Surgery (II) and Professor of Clinical Epidemiology and Health Services Research at Weill Cornell Medicine and an attending cardiac surgeon at NewYork-Presbyterian Hospital and Weill Cornell Medical Center. [1] [2] He is an expert in coronary revascularization and clinical trialist. He is known for conducting the PALACS trial, which demonstrated that posterior pericardiotomy at the time of cardiac surgery reduced the incidence of post-operative atrial fibrillation and pericardial effusion. [3]

Contents

Education

Gaudino completed medical school in 1994 graduating cum laude at the Catholic University of Rome and completed his residency in cardiac surgery at the same institution in 1999. During his residency, he completed a research fellowship at the European Homograft Bank in Brussels. Following residency, he completed a clinical fellowship in cardiac surgery at Hospital San Camillo de Lellis in Chieti with Prof. Calafiore. He joined the faculty at the Catholic University of Rome in 2000 as an assistant professor and staff cardiac surgeon. In 2014, he joined Weill Cornell Medical Center as a aortic surgery fellow for 2 years and joined the faculty at Weill Cornell Medical Center in 2016. In 2017, he was promoted to the role of Stephen and Suzanne Weiss Professor in Cardiothoracic Surgery (II). In 2020, he completed both a MS in clinical epidemiology at Weill Cornell Medical College and his PhD at Maastricht University on the topic of the radial artery in CABG. [4] In 2021, he was appointed a Professor of Clinical Epidemiology and Health Services Research at the Weill Cornell Graduate School of Medical Sciences.

Research

Gaudino's research focuses on coronary arterial bypass grafting, aortic and mitral surgery and novel adjunctive procedures in cardiac surgery. He has published over 700 peer-reviewed publications covering clinical research. [5] He is also the Assistant Dean for Clinical Trials, Director for the Joint Clinical Trials Office (JCTO), and the Director of Translational and Clinical Research for the Department of Cardiothoracic Surgery at Weill Cornell Medicine. He has published as first and last author in the New England Journal of Medicine, The Lancet and the Journal of the American Medical Association.

Clinical trialist

Gaudino is the principal investigator for the upcoming multinational ROMA and ROMA-Women trials investigating multiple arterial grafting in coronary artery bypass grafting. [6] He is also a principal investigator for the upcoming STICH3C trial, comparing coronary artery bypass grafting and percutaneous coronary intervention in patients with low ejection fraction, the ODIN trial, comparing short-term dual antiplatelet therapy to standard of care after coronary artery bypass grafting, the EPIC and PRINCE trials, two multicenter trials evaluating posterior left pericardiotomy to prevent post-operative atrial fibrillation and pericardial effusion after cardiac surgery, and the RECHARGE (Revascularization CHoices Among under-Represented Groups Evaluation) trial, a multicenter trial aiming to compare length of life and quality of life for women and underrepresented minorities with CAD who are treated with PCI compared to CABG. [7] [8] [9] [10]

Academic activities

He was part of the guideline writing committee for the 2021 ACC/AHA Myocardial Revascularization Guidelines and he is a member of the AHA Joint Committee on Clinical Practices Guidelines. [11] He was the Chair of the Coronary Artery Surgery Task Force of the European Association for Cardio-thoracic Surgery from 2017 to 2023. He is the author of Technical Aspects of Modern Coronary Artery Bypass Surgery, a textbook published in 2020 along with several book chapters published in various texts. [12] Gaudino has been funded by the NIH, PCORI, the CIHR, the British Heart Foundation, and the Austrian Science Fund continuously since 2018. He is a deputy editor of Journal of Cardiac Surgery, senior editor of Annals of Thoracic Surgery, feature editor of Journal of Thoracic and Cardiovascular Surgery, associate editor for European Journal of Cardio-Thoracic Surgery and ICVTS, and senior editor for Journal of the American College of Cardiology. He serves on the editorial board of Journal of Cardiothoracic Surgery. [13] He also serves as the Chair of the Council on Cardiovascular Surgery and Anesthesia CVSA Education and Publications Committee as well as the Chair of the Participant User File (PUF) Review Task Force of the Society of Thoracic Surgeons (Adult Cardiac Subcommittee).

Awards and honors

Gaudino has been elected as a Fellow of the American College of Cardiology, the American Heart Association and the European Board of Cardiothoracic Surgery. He has been awarded the JACC Simon Dack Award for Outstanding Scholarship in 2020 and 2021, the JTCVS Top Performance Award of the Editorial Board in 2022, and the JACC Elite Reviewer Award in 2024.

See also

Related Research Articles

<span class="mw-page-title-main">Coronary artery bypass surgery</span> Surgical procedure to restore normal blood flow to an obstructed coronary artery

Coronary artery bypass surgery, also known as coronary artery bypass graft, is a surgical procedure to treat coronary artery disease (CAD), the buildup of plaques in the arteries of the heart. It can relieve chest pain caused by CAD, slow the progression of CAD, and increase life expectancy. It aims to bypass narrowings in heart arteries by using arteries or veins harvested from other parts of the body, thus restoring adequate blood supply to the previously ischemic heart.

<span class="mw-page-title-main">Cardiothoracic surgery</span> Medical specialty involved in surgical treatment of organs inside the thorax

Cardiothoracic surgery is the field of medicine involved in surgical treatment of organs inside the thoracic cavity — generally treatment of conditions of the heart, lungs, and other pleural or mediastinal structures.

<span class="mw-page-title-main">Cardiac surgery</span> Type of surgery performed on the heart

Cardiac surgery, or cardiovascular surgery, is surgery on the heart or great vessels performed by cardiac surgeons. It is often used to treat complications of ischemic heart disease ; to correct congenital heart disease; or to treat valvular heart disease from various causes, including endocarditis, rheumatic heart disease, and atherosclerosis. It also includes heart transplantation.

<span class="mw-page-title-main">Internal thoracic artery</span> Artery of the thorax

The internal thoracic artery (ITA), also known as the internal mammary artery, is an artery that supplies the anterior chest wall and the breasts. It is a paired artery, with one running along each side of the sternum, to continue after its bifurcation as the superior epigastric and musculophrenic arteries.

Hybrid coronary revascularization (HCR) or hybrid coronary bypass is a relatively new type of heart surgery that provides an alternative to traditional coronary artery bypass surgery (CABG) or percutaneous coronary intervention by combining the two into one operation. It is this combining aspect that "hybrid" refers to. HCR is one of several types of hybrid cardiac surgery; it is not to be confused with a MIDCAB procedure, which uses the smaller thoracotomy incision but does not involve coronary stenting.

A vascular bypass is a surgical procedure performed to redirect blood flow from one area to another by reconnecting blood vessels. Often, this is done to bypass around a diseased artery, from an area of normal blood flow to another relatively normal area. It is commonly performed due to inadequate blood flow (ischemia) caused by atherosclerosis, as a part of organ transplantation, or for vascular access in hemodialysis. In general, someone's own vein (autograft) is the preferred graft material for a vascular bypass, but other types of grafts such as polytetrafluoroethylene (Teflon), polyethylene terephthalate (Dacron), or a different person's vein (allograft) are also commonly used. Arteries can also serve as vascular grafts. A surgeon sews the graft to the source and target vessels by hand using surgical suture, creating a surgical anastomosis.

<span class="mw-page-title-main">Weill Cornell Medicine</span> Medical school of Cornell University

Weill Cornell Medicine, formally the Joan & Sanford I. Weill Medical College of Cornell University, is the biomedical research and medical school of Cornell University. It is located on the Upper East Side of New York City.

<span class="mw-page-title-main">Off-pump coronary artery bypass</span>

Off-pump coronary artery bypass (OPCAB), or beating-heart surgery, is a form of coronary artery bypass graft (CABG) surgery performed without cardiopulmonary bypass as a treatment for coronary heart disease. It was primarily developed in the early 1990s by Dr. Amano Atsushi. Historically, during bypass surgeries, the heart is stopped and a heart-lung machine takes over the work of the heart and lungs. When a cardiac surgeon chooses to perform the CABG procedure off-pump (OPCAB) the heart is still beating while the graft attachments are made to bypass a blockage.

<span class="mw-page-title-main">Robert E. Michler</span>

Robert E. Michler is an American heart surgeon specializing in heart surgery, aortic and mitral valve repair, coronary artery bypass surgery, aneurysm surgery, and management of the failing heart. In 2017, Michler received the Vladimir Borakovsky Prize in Moscow from the Ministry of Health of the Russian Federation for “his personal contributions to the development of cardiovascular surgery”.

Minimally invasive cardiac surgery, encompasses various aspects of cardiac surgical procedures that can be performed with minimally invasive approach either via mini-thoracotomy or mini-sternotomy. MICS CABG or the McGinn technique is heart surgery performed through several small incisions instead of the traditional open-heart surgery that requires a median sternotomy approach. MICS CABG is a beating-heart multi-vessel procedure performed under direct vision through an anterolateral mini-thoracotomy.

Vessel harvesting is a surgical technique that may be used in conjunction with a coronary artery bypass graft (CABG). For patients with coronary artery disease, a vascular bypass may be recommended to reroute blood around blocked arteries to restore and improve blood flow and oxygen to the heart. To create the bypass graft, a surgeon will remove or "harvest" healthy blood vessels from another part of the body, either arteries from an arm or the chest, or veins from a leg. This vessel becomes a graft, with one end attaching to a blood source above and the other end below the blocked area, creating a "conduit" channel or new blood flow connection across the heart.

Robert S. Poston is an American cardiac surgeon at University of Arizona Medical Center most noted for his work in robot-assisted heart surgery and Coronary Artery Bypass Surgery.

Richard Lee is a cardiac surgeon in St. Louis, Missouri, who helped pioneer a staged Hybrid Maze, a procedure for atrial fibrillation or AFIB. combining surgery and catheter based approaches.

<span class="mw-page-title-main">Ischemic cardiomyopathy</span> Medical condition

Ischemic cardiomyopathy is a type of cardiomyopathy caused by a narrowing of the coronary arteries which supply blood to the heart. Typically, patients with ischemic cardiomyopathy have a history of acute myocardial infarction, however, it may occur in patients with coronary artery disease, but without a past history of acute myocardial infarction. This cardiomyopathy is one of the leading causes of sudden cardiac death. The adjective ischemic means characteristic of, or accompanied by, ischemia — local anemia due to mechanical obstruction of the blood supply.

In medicine, vein graft failure (VGF) is a condition in which vein grafts, which are used as alternative conduits in bypass surgeries, get occluded.

<span class="mw-page-title-main">External support</span>

In cardiac surgery and vascular surgery, external support is a type of scaffold made of metal or plastic material that is inserted over the outside of the vein graft in order to decrease the intermediate and late vein graft failure after bypass surgery.

Uwe Klima is UAE based professor of surgery and a faculty member at the Hannover Medical School, Germany. He also is the medical and managing director at German Heart Centre, Dubai.

<span class="mw-page-title-main">Anil Bhan</span> Indian cardiologist

Dr. Anil Bhan is the Chairman of Cardiac Surgery Heart Institute, Medanta Hospital, Gurugram, India. He graduated from Medical College Srinagar. He has the largest experience in aortic surgery in India since he has designed and developed more than 50 surgical instruments in the field of cardiac surgery. He was one of the team members to perform the first successful heart transplant in India in1994. He served as a co-founder of Max Heart and Vascular Institute, Saket, New Delhi, Director and Chief Co-Ordinator, Cardio thoracic and Vascular Surgery, MHVI, Saket.Additional Professor, Cardiothoracic Surgery and Vascular Surgery, AIIMS, New Delhi.

<span class="mw-page-title-main">George E. Green (doctor)</span> American cardiac surgeon (born 1932)

George E. Green is an American cardiac surgeon best known for pioneering and implementing the first surgical procedure of the left coronary artery bypass graft using the internal thoracic artery sutured to the left anterior descending coronary artery to bypass obstruction to the heart circulation in the late 1960s. He applied these techniques in 1968 at New York University Medical Center. In 1970 he was hired to establish St. Luke's Hospital's cardiac surgery program in Manhattan, New York, which by 1982 was seeing approximately 1,800 cases a year, the biggest program in the state. Green has lectured internationally on the topic, and has written numerous reports on internal thoracic artery grafting, as well as co-authoring Surgical Revascularization of the Heart: The Internal Thoracic Arteries.

John D. Puskas is an American researcher, author, inventor and cardiovascular surgeon. As of 2022, he is Professor, Cardiovascular Surgery, Icahn School of Medicine at Mount Sinai, and chairman, Department of Cardiovascular Surgery at Mount Sinai Morningside, Mount Sinai Beth Israel and Mount Sinai West. He holds 11 U.S. patents and co-founded the International Coronary Congress and the International Society for Coronary Artery Surgery. He is credited by ResearchGate with 330 publications and 15,234 citations and as of 2022 Scopus reports an h-index of 62. Puskas is known for advancing coronary artery bypass (CABG) surgery by refining surgical techniques for all-arterial, off-pump CABG and inventing finer instruments to be used for advanced coronary bypass surgical procedures. He is credited with performing the first totally thoracoscopic bilateral pulmonary vein isolation procedure. He is the co-editor of State of the Art Surgical Coronary Revascularization, the first textbook solely devoted to coronary artery surgery.

References

  1. ↑ "Mario F.L. Gaudino, M.D., Ph.D." Weill Cornell Medicine. Weill Cornell Medicine. Retrieved 14 January 2023.
  2. ↑ "Mario F. L. Gaudino, MD". NewYork-Presbyterian Hospital. Youtube. Retrieved 9 November 2023.
  3. ↑ Gaudino, Mario (4 Dec 2021). "Posterior left pericardiotomy for the prevention of atrial fibrillation after cardiac surgery: an adaptive, single-centre, single-blind, randomised, controlled trial". The Lancet. 398 (10316): 2075–2083. doi:10.1016/S0140-6736(21)02490-9. PMID   34788640. S2CID   244100606 . Retrieved 26 January 2023.
  4. ↑ "Mario F.L. Gaudino, M.D., Ph.D." Weill Cornell Medicine. Weill Cornell Medicine. Retrieved 14 January 2023.
  5. ↑ Gaudino, Mario. "Mario Gaudino". PubMed. National Library of Medicine. Retrieved 26 January 2023.
  6. ↑ "ROMA trial". ROMA trial. Weill Cornell Medicine. Retrieved 9 November 2023.
  7. ↑ Gaudino, Mario (2021). "Posterior left pericardiotomy for the prevention of atrial fibrillation after cardiac surgery: an adaptive, single-centre, single-blind, randomised, controlled trial". Lancet. 398 (10316): 2075–2083. doi:10.1016/S0140-6736(21)02490-9. PMID   34788640. S2CID   244100606 . Retrieved 14 January 2023.
  8. ↑ "Dr. Mario Gaudino Awarded Grant for STICH3C Study". Joint Clinical Trials Office. Weill Cornell Medicine. Retrieved 14 January 2023.
  9. ↑ "New International Trial to Evaluate Short-Term Ticagrelor DAPT in CABG Patients". Weill Cornell Medicine. Weill Cornell Medicine. Retrieved 9 November 2023.
  10. ↑ "Large PCORI Award Funds Comparative Study of Surgical Options for Coronary Artery Disease in Underrepresented Patient Populations". Weill Cornell Medicine. Weill Cornell Medicine. Retrieved 23 July 2024.
  11. ↑ "Mario F. L. Gaudino". Minimally Invasive and Transcatheter Cardiac Surgery Research Center. Minimally Invasive and Transcatheter Cardiac Surgery Research Center. Retrieved 14 January 2023.
  12. ↑ "Mario F.L. Gaudino, M.D., Ph.D." Weill Cornell Medicine. Weill Cornell Medicine. Retrieved 14 January 2023.
  13. ↑ "Editorial Board". Journal of Cardiothoracic Surgery. Journal of Cardiothoracic Surgery. Retrieved 9 November 2023.
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