Mark Andrew Estelle

Not to be confused with Mark Estelle.

Mark Andrew Estelle is a Canadian-American biologist known for his work elucidating the mechanism of the plant hormone, auxin using the model plant Arabidopsis thaliana . He is currently a Distinguished Professor at University of California San Diego.

Life and career

Early life

Mark Andrew Estelle was born in Calgary Alberta, Canada in 1955.^{[ citation needed ]} His undergraduate and graduate education emphasized genetic approaches to problems, regardless of species or organism which helped him develop a broad view of approaching scientific investigation (https://aspb.org/wp-content/uploads/2023/01/ASPBPioneerMember_Mark-Estelle.pdf ).^{[ citation needed ]}

Education

Mark earned his BS. degree at University of Alberta B.S. in 1978. ^[1] He earned his Ph.D. in genetics from the University of Alberta in 1983. ^[1] His doctoral research involved the fruit fly and was entitled "The analysis of a dopa decarboxylase activity variant in Drosophila melanogaster" (https://era.library.ualberta.ca/search?search=mark+A+estelle )^{[ citation needed ]}

Mark Estelle continued his scientific training as a research associate of the Michigan State University-U.S. Department of Energy Plant Research Laboratory with Dr. Chris R. Somerville (1983-86). ^{[1] [2]}

In 1986, he was hired as an Assistant Professor at Indiana University and eventually became the Indiana University Miller Chair in Plant Developmental Biology 2002-2008. ^{[3] [4]} He later moved his research lab to the University of California San Diego as a Distinguished Professor, Department of Cellular and Developmental Biology 2008-present. ^[5]

Research areas

Estelle's laboratory utilizes the plant Arabidopsis thaliana to identify auxin response pathways. His group determined that auxin response depends on the degradation of transcriptional repressors called the Aux/IAA proteins with requires the ubiquitin protein ligase E3 called SCFTIR1. ^[6]

Recognition

• HHMI investigator 2011-2018 ^{[7] [8]}
• American Association for Advancement of Science 2003 ^[9]
• National Academy of Science 2007 ^{[6] [10]}
• Pioneer Member of American Society of Plant Biologists 2023 ^[11]
• Anton Lang Memorial Lecture MSU-DOE Plant Research Laboratory 2007 ^[12]
• Woolhouse Lecture John Innes Center Norwich UK 2011 ^[13]

See also

• History of research on Arabidopsis thaliana

References

1. "Mark Estelle: University Honors and Awards: Indiana University". University Honors & Awards. Retrieved 2025-06-02.
2. "Plant Biology Tree - Mark Estelle". academictree.org. Retrieved 2025-06-02.
3. "Mark Estelle: University Honors and Awards: Indiana University". University Honors & Awards. Retrieved 2025-06-02.
4. "Mark Estelle: IU Alliance: Indiana University". IU Alliance of Distinguished and Titled Professors. Retrieved 2025-06-04.
5. "Mark Estelle".
6. "Mark Estelle – NAS". https://www.nasonline.org/ . Retrieved 2025-06-02.{{cite web}}: External link in |website= (help)
7. "Mark Estelle, PhD | Former Investigator Profile | 2011-2018". www.hhmi.org. Retrieved 2025-06-02.
8. "Grant Detail". www.moore.org. Retrieved 2025-06-04.
9. "Historic Fellows | American Association for the Advancement of Science (AAAS)". www.aaas.org. Retrieved 2025-06-02.
10. "Member Directory - NAS". https://www.nasonline.org/ . Retrieved 2025-06-02.{{cite web}}: External link in |website= (help)
11. "Pioneers Mark Estelle". American Society of Plant Biologists. Retrieved 2025-06-02.
12. "Anton Lang Award". prl.natsci.msu.edu. Retrieved 2025-06-04.
13. "The Woolhouse Lecture". John Innes Centre. Retrieved 2025-06-04.