History of research on Arabidopsis thaliana

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Arabidopsis thaliana is a first class model organism and the single most important species for fundamental research in plant molecular genetics.

Contents

A. thaliana was the first plant for which a high-quality reference genome sequence was determined and a worldwide research community has developed many other genetic resources and tools. The experimental advantages of A. thaliana have enabled many important discoveries. [1] [2] [3] [4] [5] These advantages have been extensively reviewed, [6] [7] [8] [9] [10] [11] [12] [13] [14] [15] [16] [17] [18] [19] [20] [21] as has its role in fundamental discoveries about the plant immune system, [22] natural variation, [23] [24] root biology, [25] and other areas. [26]

Early history

A. thaliana was first described by Johannes Thal, and later renamed in his honor. [24] (See the Taxonomy section of the main article.) Friedrich Laibach outlined why A. thaliana might be a good experimental system in 1943 [27] and collected a large number of natural accessions. [6] [12] [13] [24] A. thaliana is largely self-pollinating, so these accessions represent inbred strains, with high homozygosity that simplifies genetic analysis. Natural A. thaliana accessions are often referred to as "ecotypes". Laibach had earlier (1907) determined the A. thaliana chromosome number (5) as part of his PhD research. [28] Laibach's student Erna Reinholz described mutagenesis of A. thaliana with X-ray radiation in 1945. [29]

George Rédei pioneered the use of A. thaliana for fundamental studies, mutagenizing plants with ethyl methanesulfonate (EMS) and then screening them for auxotrophic defects [5] and writing an influential review in 1975. [6] Rédei distributed the standard laboratory accessions 'Columbia-0' and 'Landsberg erecta'. [8] [18]

Gerhard Röbbelen organized the first International Arabidopsis Symposium in 1965. [13] Röbbelen also started the 'Arabidopsis Information Service', a newsletter for sharing information in the community. [30] This newsletter was maintained by A.R. Kranz starting in 1974, and was published until 1990. [13]

Growing interest, 1975-1986

As molecular biology methods progressed, many investigators sought to focus community effort on a common model plant species such as petunia or tomato. [12] [13] This concept changed the emphasis of the long tradition of researchers using diverse agronomically important species such as maize, barley, and peas. [13] The A. thaliana subcommunity espoused an ethos of freely sharing information and materials, and investigators were attracted by the perceived wide-open nature of plant molecular genetics relative to other fields that were better established and thus more "crowded" and competitive. [15] The A. thaliana genome was shown to be relatively small and nonrepetitive, [31] [32] [33] which was an important advantage for early molecular methods. [13] Pioneering A. thaliana studies have used its natural filamentous pathogen Hyaloperonospora arabidopsidis , the model plant-pathogenic bacterium Pseudomonas syringae , and many other microbes. [22] A. thaliana roots are transparent and have a relatively simple radially symmetric cellular structure, facilitating analysis by microscopy. [34]

Molecular cloning, 1986-2000

Cloning of an A. thaliana gene, an alcohol dehydrogenase-encoding locus, was described in 1986, [35] by which time mutations at over 200 loci had been defined. [7]

Genetic linkage maps, QTL populations, and map-based cloning

Development of genetic maps based on scorable phenotypes [36] and molecular genetic markers facilitated map-based cloning of mutant loci from classical "forward genetic" screens. [13] [14] [17] Growing amounts of DNA sequence data facilitated development and application of such molecular markers. [37] [38] Descriptions of the first successful map-based cloning projects were published in 1992. [39] [40]

Recombinant inbred strain/line (RIL) populations were developed, notably from a cross of Columbia-0 × Lansberg erecta, [41] and used to map and clone a wide variety of quantitative trait loci.

Efficient genetic transformation

A. thaliana can be genetically transformed using Agrobacterium tumefaciens ; transformation was first reported in 1986. [42] Later work showed that transgenic seed can be obtained by simply dipping flowers into a suitable bacterial suspension. The invention/discovery of this 'floral dip' method, published in 1998, [43] made A. thaliana arguably the most easily transformed multicellular organism, and has been essential to many subsequent investigations. [13] Efficient transformation facilitated insertional mutagenesis [44] as described further below.

Transcription factors and regulation

Floral homeotic genes and the ABC model

A. thaliana geneticists made important contributions to development of the ABC model of flower development via genetic analysis of floral homeotic mutants. [45] [46] [47] [48]

Homeodomain genes

The plant homeodomain finger is so named due to its discovery in an Arabidopsis homeodomain. In 1993 Schindler et al. discovered the PHD finger in the protein HAT3.1. [49] It has since proven to be important to chromatin in a wide variety of taxa. [50]

KNOTTED-like homeobox genes, homologs of the maize KNOTTED1 gene that control shoot apical meristem identity, were described in 1994 [51] and cloning of the SHOOT-MERISTEMLESS locus was published in 1996. [52]

Genome project

An international consortium began developing a physical map for A. thaliana in 1990, and DNA sequencing and assembly efforts were formalized in the Arabidopsis Genome Initiative (AGI) in 1996. [4] [10] This work paralleled the Human Genome Project and related projects for other model organisms, including the budding yeast S. cerevisiae , the nematode C. elegans , and the fly Drosophila melanogaster , which were published in 1996, [53] 1998, [54] and 2000, [55] respectively. The project built on efforts to sequence expressed sequence tags from A. thaliana. [56] [57] Descriptions of the sequences of chromosomes 4 and 2 were published in 1999, [58] [59] and the project was completed in 2000. [60] [61] [62] [63] This represented the first reference genome for a flowering plant and facilitated comparative genomics.

Functional and comparative genomics, 2000-2010 and beyond

NSF 2010 project

A series of meetings led to an ambitious long-term NSF-funded initiative to determine the function of every A. thaliana gene by the year 2010. [64] [65] The rationale for this project was to combine new high-throughput technologies with systematic gene-family-wide studies and community resources to accelerate progress beyond what was possible via piecemeal single-laboratory studies.

Microarray and transcriptome analysis

DNA microarray technology was rapidly adopted for A. thaliana research and led to the development of "atlases" of gene expression in different tissues and under different conditions.

Large-scale "reverse genetic" analysis

The A. thaliana genome sequence, low-cost Sanger sequencing, and ease of transformation facilated genome-wide mutagenesis, yielding collections of sequence-indexed transposon mutant and (especially) T-DNA mutant lines. [66] [67] The ease and speed of ordering mutant seed from stock centers dramatically accelerated "reverse genetic" study of many gene families; the Arabidopsis Biological Resource Center and the Nottingham Arabidopsis Stock Centre were important in this regard, and information on stock availability was integrated into The Arabidopsis Information Resource database. [26]

Syngenta developed and publicly shared a significant T-DNA mutant population, the Syngenta Arabidopsis Insertion Library (SAIL) collection. Industry investment in A. thaliana research suffered a setback in the closure of Syngenta's Torrey Mesa Research Institute (TMRI), [68] but remained robust. Mendel Biotechnology overexpressed the vast majority of A. thaliana transcription factors to generate leads for genetic engineering. Cereon Genomics, a subsidiary of Monsanto, sequenced the Landsberg erecta accession (at lower coverage than the Col-0 project) and shared the assembly, along with other sequence marker data. [38] [69] [70]

RNA silencing

A. thaliana quickly became an important model for the study of plant small RNAs. The argonaute1 mutant, named for its resemblance to an Argonauta octopuses, [71] was the namesake for the Argonaute protein family central to silencing. [16] Forward genetic screens focused on vegetative phase change uncovered many genes controlling small RNA biogenesis. Multiple groups identified mutations in the DICER-LIKE1 gene (encoding the main DICER protein controlling microRNA biogenesis in plants) that cause strong developmental defects. [72] A. thaliana became an important model for RNA-directed DNA methylation (transcriptional silencing), partly because many A. thaliana methylation mutants are viable, which is not the case for several model animals (in which such mutations cause lethality). [16]

Growing popularity of other model plants

As the NSF 2010 project neared completion, there was a perceived decrease in funding agency interest in A. thaliana, evidenced by the cessation of USDA funding for A. thaliana research[ citation needed ] and the end of NSF funding for the TAIR database. [73] This trend coincided with the progress of the (US NSF-supported) National Plant Genome Initiative, which began in 1998 and put an increased emphasis on crops. Draft genome sequence for rice were published in 2002 [74] [75] and followed by publications for sorghum [76] and maize [77] in 2009. A draft genome of the model tree Populus trichocarpa was published in 2006. [78] The draft genome of Brachypodium distachyon , a short-statured model grass (Poaceae) was published in 2010. [79] The Joint Genome Institute of the United States Department of Energy identified poplar, sorghum, B. distachyon, model C4 grass Setaria viridis (foxtail millet), model moss Physcomitrella patens , model alga Chlamydomonas reinhardtii , and soybean as its "flagship" species for plant genomics geared towards bioenergy applications. [80]

Awards

Well established investigators including Ronald W. Davis, Gerald Fink, and Frederick M. Ausubel adopted A. thaliana as a model in the 1980s, attracting interest. [81] [9]

Elliot Meyerowitz and Chris R. Somerville were awarded the Balzan Prize in 2006 for their work developing A. thaliana as a model. [82] Thirteen prominent American A. thaliana geneticists were selected as investigators of the prestigious Howard Hughes Medical Institute and Gordon and Betty Moore Foundation in 2011: [83] [84] Philip Benfey, Dominique Bergmann, Simon Chan, Xuemei Chen, Jeff Dangl, Xinnian Dong, Joseph R. Ecker, Mark Estelle, Sheng Yang He, Robert A. Martienssen, Elliot Meyerowitz, Craig Pikaard, and Keiko Torii. (Also selected were wheat geneticist Jorge Dubcovsky and photosynthesis researcher Krishna Niyogi, who has extensively used A. thaliana along with the alga Chlamydomonas reinhardtii . [85] ) Prior to this, a handful of A. thaliana geneticists had become HHMI investigators: Joanne Chory (1997, [86] also awarded a 2018 Breakthrough Prize in Life Sciences [87] ), Daphne Preuss (2000-2006), [88] and Steve Jacobsen (2005). [89] Caroline Dean was awarded many honors including the 2020 Wolf Prize in Agriculture for "pioneering discoveries in flowering time control and epigenetic basis of vernalization" made with A. thaliana. [90]

Impact of second- and third-generation sequencing technology

A. thaliana continues to be the subject of intense study using new technologies such as high-throughput sequencing. Direct sequencing of cDNA ("RNA-Seq") largely replaced microarray analysis of gene expression, and several studies sequenced cDNA from single cells (scRNA-seq), particularly from root tissue. [25] Mapping of mutations from forward screens is increasingly done with direct genome sequencing, combined in some cases with bulked segregant analysis or backcrossing. [91] A. thaliana is a premier model for studies of the plant microbiome and natural genetic variation, [16] [23] [24] including genome-wide association studies. Short RNA-guided DNA editing with CRISPR tools has been applied to A. thaliana since 2013. [92]

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References

  1. ↑ North, Geoffrey (1985-05-30). "Plant genetics: A plant joins the pantheon at last?". Nature. 315 (6018): 366–367. Bibcode:1985Natur.315Q.366N. doi: 10.1038/315366a0 . ISSN   1476-4687.
  2. ↑ Nicholas Wade (1999). "Geneticists tap secrets of 'the weed'". New York Times.
  3. ↑ Andrew Pollack (2000). "First complete plant genetic sequence is determined". New York Times.
  4. 1 2 Pennisi, Elizabeth (2000-10-06). "Arabidopsis comes of age". Science. 290 (5489): 32–35. doi:10.1126/science.290.5489.32. ISSN   0036-8075. PMID   11183143. S2CID   82370817.
  5. 1 2 Potter, Erik (2014). "From Apathy to Apogee". MIZZOU Magazine. hdl:10355/54855. Archived from the original on 2014-10-12. Retrieved 2014-08-22.
  6. 1 2 3 Redei, G P (1975-12-01). "Arabidopsis as a genetic tool". Annual Review of Genetics. 9 (1): 111–127. doi:10.1146/annurev.ge.09.120175.000551. ISSN   0066-4197. PMID   1108762.
  7. 1 2 Estelle, M. A.; Somerville, Chris R. (1986). "The mutants of Arabidopsis". Trends in Genetics. 2: 89–93. doi:10.1016/0168-9525(86)90190-3.
  8. 1 2 Rédei, George P. (1992). "A heuristic glance at the past of Arabidopsis genetics". Methods in Arabidopsis Research. WORLD SCIENTIFIC. pp. 1–15. doi:10.1142/9789814439701_0001. ISBN   978-981-02-0904-9 . Retrieved 2022-02-10.
  9. 1 2 Fink, Gerald R. (1998-06-01). "Anatomy of a Revolution". Genetics. 149 (2): 473–477. doi:10.1093/genetics/149.2.473. ISSN   0016-6731. PMC   1460179 . PMID   9611166 . Retrieved 2017-10-22.
  10. 1 2 Meinke, David W.; Cherry, J. Michael; Dean, Caroline; Rounsley, Steven D.; Koornneef, Maarten (1998-10-23). "Arabidopsis thaliana: A Model Plant for Genome Analysis". Science. 282 (5389): 662–682. Bibcode:1998Sci...282..662M. CiteSeerX   10.1.1.462.4735 . doi:10.1126/science.282.5389.662. ISSN   0036-8075. PMID   9784120.
  11. ↑ Somerville, Chris; Somerville, Shauna (1999-07-16). "Plant functional genomics". Science. 285 (5426): 380–383. CiteSeerX   10.1.1.467.4876 . doi:10.1126/science.285.5426.380. ISSN   0036-8075. PMID   10411495.
  12. 1 2 3 Meyerowitz, Elliot M. (2001-01-01). "Prehistory and History of Arabidopsis Research". Plant Physiology. 125 (1): 15–19. doi:10.1104/pp.125.1.15. ISSN   0032-0889. PMC   1539315 . PMID   11154286 . Retrieved 2021-11-01.
  13. 1 2 3 4 5 6 7 8 9 Somerville, Chris; Koornneef, Maarten (2002). "A fortunate choice: the history of Arabidopsis as a model plant". Nature Reviews Genetics. 3 (11): 883–889. doi:10.1038/nrg927. ISSN   1471-0056. PMID   12415318. S2CID   37515057.
  14. 1 2 Page, Damian R.; Grossniklaus, Ueli (2002-02-01). "The art and design of genetic screens: Arabidopsis thaliana". Nature Reviews Genetics. 3 (2): 124–136. doi:10.1038/nrg730. ISSN   1471-0064. PMID   11836506. S2CID   431110 . Retrieved 2022-01-28.
  15. 1 2 Leonelli, Sabina (2007). "Growing weed, producing knowledge: An epistemic history of Arabidopsis thaliana". History and Philosophy of the Life Sciences. 29 (2): 193–223. ISSN   0391-9714. JSTOR   23334228. PMID   18564512 . Retrieved 2023-08-31.
  16. 1 2 3 4 Jones, Alan M.; Chory, Joanne; Dangl, Jeffery L.; Estelle, Mark; Jacobsen, Steven E.; Meyerowitz, Elliot M.; Nordborg, Magnus; Weigel, Detlef (2008-06-13). "The impact of Arabidopsis on human health: diversifying our portfolio". Cell. 133 (6): 939–943. doi:10.1016/j.cell.2008.05.040. ISSN   0092-8674. PMC   3124625 . PMID   18555767.
  17. 1 2 Koornneef, Maarten; Meinke, David (2010-03-01). "The development of Arabidopsis as a model plant". The Plant Journal. 61 (6): 909–921. doi: 10.1111/j.1365-313X.2009.04086.x . ISSN   1365-313X. PMID   20409266.
  18. 1 2 Somssich, Marc (2019-02-28). A short history of Arabidopsis thaliana (L.) Heynh. Columbia-0. PeerJ Preprints. doi: 10.7287/peerj.preprints.26931v5 . Retrieved 2021-06-20.
  19. ↑ Meinke, David W. (2020). "Genome-wide identification of EMBRYO-DEFECTIVE (EMB) genes required for growth and development in Arabidopsis". New Phytologist. 226 (2): 306–325. doi: 10.1111/nph.16071 . ISSN   1469-8137. PMID   31334862. S2CID   198171553.
  20. ↑ Provart, Nicholas J; Brady, Siobhan M; Parry, Geraint; Schmitz, Robert J; Queitsch, Christine; Bonetta, Dario; Waese, Jamie; Schneeberger, Korbinian; Loraine, Ann E (2021-04-01). "Anno genominis XX: 20 years of Arabidopsis genomics". The Plant Cell. 33 (4): 832–845. doi:10.1093/plcell/koaa038. ISSN   1040-4651. PMC   8226293 . PMID   33793861 . Retrieved 2022-04-25.
  21. ↑ Somssich, Marc (2022). "The dawn of plant molecular biology: How three key methodologies paved the way". Current Protocols. 2 (4): –417. doi: 10.1002/cpz1.417 . ISSN   2691-1299 . Retrieved 2024-11-01.
  22. 1 2 Nishimura, Marc T.; Dangl, Jeffery L. (2010-03-01). "Arabidopsis and the plant immune system". The Plant Journal. 61 (6): 1053–1066. doi:10.1111/j.1365-313X.2010.04131.x. ISSN   1365-313X. PMC   2859471 . PMID   20409278.
  23. 1 2 Weigel, Detlef (2012-01-01). "Natural Variation in Arabidopsis: From Molecular Genetics to Ecological Genomics". Plant Physiology. 158 (1): 2–22. doi:10.1104/pp.111.189845. ISSN   0032-0889. PMC   3252104 . PMID   22147517.
  24. 1 2 3 4 Krämer, Ute (2015-03-25). "Planting molecular functions in an ecological context with Arabidopsis thaliana". eLife. 4: –06100. doi: 10.7554/eLife.06100 . ISSN   2050-084X. PMC   4373673 . PMID   25807084.
  25. 1 2 Shahan, Rachel; Nolan, Trevor M; Benfey, Philip N (2021-10-13). "Single-cell analysis of cell identity in the Arabidopsis root apical meristem: insights and opportunities". Journal of Experimental Botany. 72 (19): 6679–6686. doi:10.1093/jxb/erab228. ISSN   0022-0957. PMC   8513161 . PMID   34018001 . Retrieved 2022-02-10.
  26. 1 2 Provart, Nicholas J.; Alonso, Jose; Assmann, Sarah M.; Bergmann, Dominique; Brady, Siobhan M.; Brkljacic, Jelena; Browse, John; Chapple, Clint; Colot, Vincent; Cutler, Sean; Dangl, Jeff; Ehrhardt, David; Friesner, Joanna D.; Frommer, Wolf B.; Grotewold, Erich; Meyerowitz, Elliot; Nemhauser, Jennifer; Nordborg, Magnus; Pikaard, Craig; Shanklin, John; Somerville, Chris; Stitt, Mark; Torii, Keiko U.; Waese, Jamie; Wagner, Doris; McCourt, Peter (2016-02-01). "50 years of Arabidopsis research: highlights and future directions". New Phytologist. 209 (3): 921–944. doi: 10.1111/nph.13687 . ISSN   1469-8137. PMID   26465351.
  27. ↑ Laibach, Frederick (1943). "Arabidopsis thaliana (L.) Heynh. als Objekt für genetische und entwicklungsphysiologische Untersuchungen". Bot. Archiv. 44: 439–455.
  28. ↑ Laibach, Friedrich (1907). Zur Frage nach der Individualität der Chromosomen im Pflanzenreich (Thesis).
  29. ↑ Reinholz, Erna (1945). Auslösung von Röntgen-Mutationen bei Arabidopsis thaliana L. Heynh. und ihre Bedeutung für die Pflanzenzüchtung und Evolutionstheorie: Nebst Zusammenfassg (Thesis).
  30. ↑ Röbbelen, Gerhard (1964). "Preface". The Arabidopsis Information Service. 1.
  31. ↑ Leutwiler, Leslie S.; Hough-Evans, Barbara R.; Meyerowitz, Elliot M. (1984-04-01). "The DNA of Arabidopsis thaliana". Molecular and General Genetics. 194 (1–2): 15–23. doi:10.1007/BF00383491. ISSN   0026-8925. S2CID   22819802.
  32. ↑ Pruitt, Robert E.; Meyerowitz, Elliot M. (1986-01-20). "Characterization of the genome of Arabidopsis thaliana". Journal of Molecular Biology. 187 (2): 169–183. doi:10.1016/0022-2836(86)90226-3. ISSN   0022-2836. PMID   3701864 . Retrieved 2017-10-03.
  33. ↑ Meyerowitz, Elliot M. (2023-01-09). "Elliot M. Meyerowitz". Current Biology. 33 (1): –4–R6. Bibcode:2023CBio...33R...4M. doi: 10.1016/j.cub.2022.11.040 . ISSN   0960-9822. PMID   36626864. S2CID   255548117.
  34. ↑ Dolan, L.; Janmaat, K.; Willemsen, V.; Linstead, P.; Poethig, S.; Roberts, K.; Scheres, B. (1993-09-01). "Cellular organisation of the Arabidopsis thaliana root". Development. 119 (1): 71–84. doi:10.1242/dev.119.1.71. hdl: 1874/12639 . ISSN   0950-1991. PMID   8275865 . Retrieved 2022-02-10.
  35. ↑ Chang, C.; Meyerowitz, E. M. (1986-03-01). "Molecular cloning and DNA sequence of the Arabidopsis thaliana alcohol dehydrogenase gene". Proceedings of the National Academy of Sciences. 83 (5): 1408–1412. Bibcode:1986PNAS...83.1408C. doi: 10.1073/pnas.83.5.1408 . ISSN   0027-8424. PMC   323085 . PMID   2937058.
  36. ↑ Koornneef, M.; van Eden, J.; Hanhart, C. J.; Stam, P.; Braaksma, F. J.; Feenstra, W. J. (1983-07-01). "Linkage map of Arabidopsis thaliana". Journal of Heredity. 74 (4): 265–272. doi:10.1093/oxfordjournals.jhered.a109781. ISSN   0022-1503 . Retrieved 2023-08-26.
  37. ↑ Lukowitz, Wolfgang; Gillmor, C. Stewart; Scheible, Wolf-Rüdiger (2000-07-01). "Positional Cloning in Arabidopsis. Why It Feels Good to Have a Genome Initiative Working for You". Plant Physiology. 123 (3): 795–806. doi:10.1104/pp.123.3.795. ISSN   0032-0889. PMC   1539260 . PMID   10889228.
  38. 1 2 Jander, Georg; Norris, Susan R.; Rounsley, Steven D.; Bush, David F.; Levin, Irena M.; Last, Robert L. (2002-06-01). "Arabidopsis Map-Based Cloning in the Post-Genome Era". Plant Physiology. 129 (2): 440–450. doi:10.1104/pp.003533. ISSN   0032-0889. PMC   1540230 . PMID   12068090.
  39. ↑ Arondel, V.; Lemieux, B.; Hwang, I.; Gibson, S.; Goodman, H. M.; Somerville, C. R. (1992-11-20). "Map-based cloning of a gene controlling omega-3 fatty acid desaturation in Arabidopsis". Science. 258 (5086): 1353–1355. Bibcode:1992Sci...258.1353A. doi:10.1126/science.1455229. ISSN   0036-8075. PMID   1455229.
  40. ↑ Giraudat, J; Hauge, B M; Valon, C; Smalle, J; Parcy, F; Goodman, H M (1992-10-01). "Isolation of the Arabidopsis ABI3 gene by positional cloning". The Plant Cell. 4 (10): 1251–1261. doi:10.1105/tpc.4.10.1251. ISSN   1040-4651. PMC   160212 . PMID   1359917 . Retrieved 2021-12-25.
  41. ↑ Lister, Clare; Dean, Caroline (1993). "Recombinant inbred lines for mapping RFLP and phenotypic markers in Arabidopsis thaliana". The Plant Journal. 4 (4): 745–750. doi: 10.1046/j.1365-313X.1993.04040745.x . ISSN   1365-313X.
  42. ↑ Lloyd, Alan M.; Barnason, Arlene R.; Rogers, Stephen G.; Byrne, Michael C.; Fraley, Robert T.; Horsch, Robert B. (1986-10-24). "Transformation of Arabidopsis thaliana with Agrobacterium tumefaciens". Science. 234 (4775): 464–466. Bibcode:1986Sci...234..464L. doi:10.1126/science.234.4775.464. PMID   17792019. S2CID   22125701.
  43. ↑ Clough, Steven J.; Bent, Andrew F. (1998-12-01). "Floral dip: a simplified method for Agrobacterium-mediated transformation of Arabidopsis thaliana". The Plant Journal. 16 (6): 735–743. doi:10.1046/j.1365-313x.1998.00343.x. ISSN   1365-313X. PMID   10069079. S2CID   410286.
  44. ↑ Krysan, Patrick J.; Young, Jeffery C.; Sussman, Michael R. (1999-12-01). "T-DNA as an Insertional Mutagen in Arabidopsis". The Plant Cell. 11 (12): 2283–2290. doi:10.1105/tpc.11.12.2283. ISSN   1040-4651. PMC   144136 . PMID   10590158.
  45. ↑ Enrico S. Coen; Elliot M. Meyerowitz (1991). "The war of the whorls: Genetic interactions controlling flower development". Nature. 353 (6339): 31–37. Bibcode:1991Natur.353...31C. doi:10.1038/353031a0. PMID   1715520. S2CID   4276098.
  46. ↑ Bowman, John L.; Smyth, David R.; Meyerowitz, Elliot M. (2012-11-15). "The ABC model of flower development: then and now". Development. 139 (22): 4095–4098. doi: 10.1242/dev.083972 . ISSN   0950-1991. PMID   23093420.
  47. ↑ Irish, Vivian (2017-09-11). "The ABC model of floral development". Current Biology. 27 (17): –887–R890. Bibcode:2017CBio...27.R887I. doi: 10.1016/j.cub.2017.03.045 . ISSN   0960-9822. PMID   28898659.
  48. ↑ Smyth, David R (2023-08-01). "How flower development genes were identified using forward genetic screens in Arabidopsis thaliana". Genetics. 224 (4). doi:10.1093/genetics/iyad102. ISSN   1943-2631. PMC   10411571 . PMID   37294732 . Retrieved 2023-08-26.
  49. ↑ Schindler U, Beckmann H, Cashmore AR (July 1993). "HAT3.1, a novel Arabidopsis homeodomain protein containing a conserved cysteine-rich region". The Plant Journal. 4 (1): 137–50. doi: 10.1046/j.1365-313x.1993.04010137.x . PMID   8106082.
  50. ↑ Gatchalian, Jovylyn, and Tatiana G. Kutateladze. Zhou, Ming-Ming, ed. "PHD fingers as histone readers." In Histone Recognition, pp. 27-47. Springer, Cham, 2015.
  51. ↑ Lincoln, C.; Long, J.; Yamaguchi, J.; Serikawa, K.; Hake, S. (1994-12-01). "A knotted1-like homeobox gene in Arabidopsis is expressed in the vegetative meristem and dramatically alters leaf morphology when overexpressed in transgenic plants". The Plant Cell Online. 6 (12): 1859–1876. doi:10.1105/tpc.6.12.1859. ISSN   1040-4651. PMC   160567 . PMID   7866029 . Retrieved 2013-05-13.
  52. ↑ Long, Jeff A.; Moan, Erich I.; Medford, June I.; Barton, M. Kathryn (1996-01-04). "A member of the KNOTTED class of homeodomain proteins encoded by the STM gene of Arabidopsis". Nature. 379 (6560): 66–69. Bibcode:1996Natur.379...66L. doi:10.1038/379066a0. PMID   8538741. S2CID   4280122 . Retrieved 2013-05-13.
  53. ↑ Goffeau A, Barrell BG, Bussey H, Davis RW, Dujon B, Feldmann H, Galibert F, Hoheisel JD, Jacq C, Johnston M, Louis EJ, Mewes HW, Murakami Y, Philippsen P, Tettelin H, Oliver SG (1996). "Life with 6000 genes". Science. 274 (5287): 546, 563–67. Bibcode:1996Sci...274..546G. doi:10.1126/science.274.5287.546. PMID   8849441. S2CID   16763139.
  54. ↑ The C. elegans Sequencing Consortium (1998). "Genome Sequence of the Nematode C. elegans: A Platform for Investigating Biology". Science. 282 (5396): 2012–2018. Bibcode:1998Sci...282.2012.. doi:10.1126/science.282.5396.2012. PMID   9851916.
  55. ↑ Adams MD, Celniker SE, Holt RA, Evans CA, Gocayne JD, Amanatides PG, et al. (March 2000). "The genome sequence of Drosophila melanogaster". Science. 287 (5461): 2185–95. Bibcode:2000Sci...287.2185.. CiteSeerX   10.1.1.549.8639 . doi:10.1126/science.287.5461.2185. PMID   10731132.
  56. ↑ Newman, T.; Bruijn, F. J. de; Green, P.; Keegstra, K.; Kende, H.; McIntosh, L.; Ohlrogge, J.; Raikhel, Natasha; Somerville, S.; Thomashow, M.; Retzel, E.; Somerville, C. (1994-12-01). "Genes galore: A summary of methods for accessing results from large-scale partial sequencing of anonymous Arabidopsis cDNA clones". Plant Physiology. 106 (4): 1241–1255. doi:10.1104/pp.106.4.1241. ISSN   0032-0889. PMC   159661 . PMID   7846151.
  57. ↑ Somerville, S; Somerville, C (1996). "Arabidopsis at 7: still growing like a weed". The Plant Cell. 8 (11): 1917–1933. doi:10.2307/3870402. ISSN   1040-4651. JSTOR   3870402. PMC   161324 . PMID   8953765.
  58. ↑ Mayer, K.; Schüller, C.; Wambutt, R.; Murphy, G.; Volckaert, G.; Pohl, T.; Düsterhöft, A.; Stiekema, W.; Entian, K.-D.; Terryn, N.; Harris, B.; Ansorge, W.; Brandt, P.; Grivell, L.; Rieger, M.; Weichselgartner, M.; de Simone, V.; Obermaier, B.; Mache, R.; Müller, M.; Kreis, M.; Delseny, M.; Puigdomenech, P.; Watson, M.; Schmidtheini, T.; Reichert, B.; Portatelle, D.; Perez-Alonso, M.; Boutry, M.; et al. (1999-12-16). "Sequence and analysis of chromosome 4 of the plant Arabidopsis thaliana". Nature. 402 (6763): 769–777. Bibcode:1999Natur.402..769M. doi:10.1038/47134. ISSN   0028-0836. PMID   10617198. S2CID   205062996.
  59. ↑ Lin, Xiaoying; Kaul, Samir; Rounsley, Steve; Shea, Terrance P.; Benito, Maria-Ines; Town, Christopher D.; Fujii, Claire Y.; Mason, Tanya; Bowman, Cheryl L.; Barnstead, Mary; Feldblyum, Tamara V.; Buell, C. Robin; Ketchum, Karen A.; Lee, John; Ronning, Catherine M.; Koo, Hean L.; Moffat, Kelly S.; Cronin, Lisa A.; Shen, Mian; Pai, Grace; Van Aken, Susan; Umayam, Lowell; Tallon, Luke J.; Gill, John E.; Adams, Mark D.; Carrera, Ana J.; Creasy, Todd H.; Goodman, Howard M.; Somerville, Chris R.; Copenhaver, Greg P.; Preuss, Daphne; Nierman, William C.; White, Owen; Eisen, Jonathan A.; Salzberg, Steven L.; Fraser, Claire M.; Venter, J. Craig (1999-12-16). "Sequence and analysis of chromosome 2 of the plant Arabidopsis thaliana". Nature. 402 (6763): 761–768. Bibcode:1999Natur.402..761L. doi: 10.1038/45471 . ISSN   0028-0836. PMID   10617197.
  60. ↑ The Arabidopsis Genome Initiative (2000-12-14). "Analysis of the genome sequence of the flowering plant Arabidopsis thaliana". Nature. 408 (6814): 796–815. Bibcode:2000Natur.408..796T. doi: 10.1038/35048692 . ISSN   0028-0836. PMID   11130711.
  61. ↑ Theologis, Athanasios; Ecker, Joseph R.; Palm, Curtis J.; Federspiel, Nancy A.; Kaul, Samir; White, Owen; Alonso, Jose; Altafi, Hootan; Araujo, Rina; Bowman, Cheryl L.; Brooks, Shelise Y.; Buehler, Eugen; Chan, April; Chao, Qimin; Chen, Huaming; Cheuk, Rosa F.; Chin, Christina W.; Chung, Mike K.; Conn, Lane; Conway, Aaron B.; Conway, Andrew R.; Creasy, Todd H.; Dewar, Ken; Dunn, Patrick; Etgu, Pelin; Feldblyum, Tamara V.; Feng, JiDong; Fong, Betty; Fujii, Claire Y.; Gill, John E.; Goldsmith, Andrew D.; Haas, Brian; Hansen, Nancy F.; Hughes, Beth; Huizar, Lucas; Hunter, Jonathan L.; Jenkins, Jennifer; Johnson-Hopson, Chanda; Khan, Shehnaz; Khaykin, Elizabeth; Kim, Christopher J.; Koo, Hean L.; Kremenetskaia, Irina; Kurtz, David B.; Kwan, Andrea; Lam, Bao; Langin-Hooper, Stephanie; Lee, Andrew; Lee, Jeong M.; Lenz, Catherine A.; Li, Joycelyn H.; Li, YaPing; Lin, Xiaoying; Liu, Shirley X.; Liu, Zhaoying A.; Luros, Jason S.; Maiti, Rama; Marziali, Andre; Militscher, Jennifer; Miranda, Molly; Nguyen, Michelle; Nierman, William C.; Osborne, Brian I.; Pai, Grace; Peterson, Jeremy; Pham, Paul K.; Rizzo, Michael; Rooney, Timothy; Rowley, Don; Sakano, Hitomi; Salzberg, Steven L.; Schwartz, Jody R.; Shinn, Paul; Southwick, Audrey M.; Sun, Hui; Tallon, Luke J.; Tambunga, Gabriel; Toriumi, Mitsue J.; Town, Christopher D.; Utterback, Teresa; Van Aken, Susan; Vaysberg, Maria; Vysotskaia, Valentina S.; Walker, Michelle; Wu, Dongying; Yu, Guixia; Fraser, Claire M.; Venter, J. Craig; Davis, Ronald W. (2000-12-14). "Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana". Nature. 408 (6814): 816–820. Bibcode:2000Natur.408..816T. doi:10.1038/35048500. ISSN   0028-0836. PMID   11130712. S2CID   4419318.
  62. ↑ Consortium, European Union Chromosome 3 Arabidopsis Genome Sequencing; Research, The Institute for Genomic; Institute, Kazusa DNA Research (2000-12-14). "Sequence and analysis of chromosome 3 of the plant Arabidopsis thaliana ". Nature. 408 (6814): 820–2. Bibcode:2000Natur.408..820E. doi:10.1038/35048706. ISSN   1476-4687. PMID   11130713. S2CID   186245749.{{cite journal}}: CS1 maint: numeric names: authors list (link)
  63. ↑ Institute, Kazusa DNA Research; Consortium, The Cold Spring Harbor and Washington University Sequencing; Consortium, The European Union Arabidopsis Genome Sequencing; Research (IPK), Institute of Plant Genetics and Crop Plant (2000-12-14). "Sequence and analysis of chromosome 5 of the plant Arabidopsis thaliana". Nature. 408 (6814): 823–6. Bibcode:2000Natur.408..823K. doi:10.1038/35048507. ISSN   1476-4687. PMID   11130714. S2CID   186243532.
  64. ↑ Chory, Joanne; Ecker, Joseph R.; Briggs, Steve; Caboche, Michel; Coruzzi, Gloria M.; Cook, Doug; Dangl, Jeffrey; Grant, Sarah; Guerinot, Mary Lou; Henikoff, Steven; Martienssen, Rob; Okada, Kiyotaka; Raikhel, Natasha V.; Somerville, Chris R.; Weigel, Detlef (2000-06-01). "National Science Foundation-Sponsored Workshop Report: "The 2010 Project." Functional Genomics and the Virtual Plant. A Blueprint for Understanding How Plants Are Built and How to Improve Them". Plant Physiology. 123 (2): 423–426. doi:10.1104/pp.123.2.423. ISSN   0032-0889. PMC   1539254 . PMID   10859172.
  65. ↑ Somerville, Chris; Dangl, Jeff (2000-12-15). "Plant Biology in 2010". Science. 290 (5499): 2077–2078. doi:10.1126/science.290.5499.2077. ISSN   0036-8075. PMID   11187833. S2CID   82836727.
  66. ↑ Alonso, José M.; Stepanova, Anna N.; Leisse, Thomas J.; Kim, Christopher J.; Chen, Huaming; Shinn, Paul; Stevenson, Denise K.; Zimmerman, Justin; Barajas, Pascual; Cheuk, Rosa; Gadrinab, Carmelita; Heller, Collen; Jeske, Albert; Koesema, Eric; Meyers, Cristina C.; Parker, Holly; Prednis, Lance; Ansari, Yasser; Choy, Nathan; Deen, Hashim; Geralt, Michael; Hazari, Nisha; Hom, Emily; Karnes, Meagan; Mulholland, Celene; Ndubaku, Ral; Schmidt, Ian; Guzman, Plinio; Aguilar-Henonin, Laura; Schmid, Markus; Weigel, Detlef; Carter, David E.; Marchand, Trudy; Risseeuw, Eddy; Brogden, Debra; Zeko, Albana; Crosby, William L.; Berry, Charles C.; Ecker, Joseph R. (2003-08-01). "Genome-Wide Insertional Mutagenesis of Arabidopsis thaliana". Science. 301 (5633): 653–657. Bibcode:2003Sci...301..653A. doi:10.1126/science.1086391. ISSN   0036-8075. PMID   12893945. S2CID   30755818.
  67. ↑ O'Malley, Ronan C.; Ecker, Joseph R. (2010-03-01). "Linking genotype to phenotype using the Arabidopsis unimutant collection". The Plant Journal. 61 (6): 928–940. doi: 10.1111/j.1365-313X.2010.04119.x . ISSN   1365-313X. PMID   20409268.
  68. ↑ Vogel, Gretchen (2002-12-13). "Retreat From Torrey Mesa: A Chill Wind in Ag Research". Science. 298 (5601): 2106. doi:10.1126/science.298.5601.2106a. PMID   12481105. S2CID   44440094 . Retrieved 2022-02-23.
  69. ↑ Rounsley, Steven (2003-10-01). "Sharing the Wealth. The Mechanics of a Data Release from Industry". Plant Physiology. 133 (2): 438–440. doi:10.1104/pp.103.024141. ISSN   0032-0889. PMC   523870 . PMID   14555770 . Retrieved 2022-02-23.
  70. ↑ Rounsley, Steven D.; Last, Robert L. (2010). "Shotguns and SNPs: how fast and cheap sequencing is revolutionizing plant biology". The Plant Journal. 61 (6): 922–927. doi:10.1111/j.1365-313X.2009.04030.x. ISSN   1365-313X. PMID   20409267 . Retrieved 2022-02-23.
  71. ↑ Bohmert, Karen; Camus, Isabelle; Bellini, Catherine; Bouchez, David; Caboche, Michel; Benning, Christoph (1998-01-01). "AGO1 defines a novel locus of Arabidopsis controlling leaf development". The EMBO Journal. 17 (1): 170–180. doi:10.1093/emboj/17.1.170. ISSN   0261-4189. PMC   1170368 . PMID   9427751.
  72. ↑ Schauer, Stephen E; Jacobsen, Steven E; Meinke, David W; Ray, Animesh (2002-11-01). "DICER-LIKE1: blind men and elephants in Arabidopsis development". Trends in Plant Science. 7 (11): 487–491. doi:10.1016/S1360-1385(02)02355-5. ISSN   1360-1385. PMID   12417148 . Retrieved 2017-06-09.
  73. ↑ Abbott, Alison (2009-11-18). "Plant genetics database at risk as funds run dry". Nature News. 462 (7271): 258–259. doi: 10.1038/462258b . ISSN   0028-0836. PMID   19924178.
  74. ↑ Yu, Jun; et al. (2002-04-05). "A draft sequence of the rice genome (Oryza sativa L. ssp. indica)". Science. 296 (5565): 79–92. Bibcode:2002Sci...296...79Y. doi:10.1126/science.1068037. PMID   11935017. S2CID   208529258 . Retrieved 2021-10-01.
  75. ↑ Goff, Stephen A.; Ricke, Darrell; Lan, Tien-Hung; Presting, Gernot; Wang, Ronglin; Dunn, Molly; Glazebrook, Jane; Sessions, Allen; Oeller, Paul; Varma, Hemant; Hadley, David; Hutchison, Don; Martin, Chris; Katagiri, Fumiaki; Lange, B. Markus; Moughamer, Todd; Xia, Yu; Budworth, Paul; Zhong, Jingping; Miguel, Trini; Paszkowski, Uta; Zhang, Shiping; Colbert, Michelle; Sun, Wei-lin; Chen, Lili; Cooper, Bret; Park, Sylvia; Wood, Todd Charles; Mao, Long; Quail, Peter; Wing, Rod; Dean, Ralph; Yu, Yeisoo; Zharkikh, Andrey; Shen, Richard; Sahasrabudhe, Sudhir; Thomas, Alun; Cannings, Rob; Gutin, Alexander; Pruss, Dmitry; Reid, Julia; Tavtigian, Sean; Mitchell, Jeff; Eldredge, Glenn; Scholl, Terri; Miller, Rose Mary; Bhatnagar, Satish; Adey, Nils; Rubano, Todd; Tusneem, Nadeem; Robinson, Rosann; Feldhaus, Jane; Macalma, Teresita; Oliphant, Arnold; Briggs, Steven (2002-04-05). "A draft sequence of the rice genome (Oryza sativa L. ssp. japonica)". Science. 296 (5565): 92–100. Bibcode:2002Sci...296...92G. doi:10.1126/science.1068275. PMID   11935018. S2CID   2960202 . Retrieved 2021-10-01.
  76. ↑ Paterson, Andrew H.; Bowers, John E.; Bruggmann, Rémy; Dubchak, Inna; Grimwood, Jane; Gundlach, Heidrun; Haberer, Georg; Hellsten, Uffe; Mitros, Therese; Poliakov, Alexander; Schmutz, Jeremy; Spannagl, Manuel; Tang, Haibao; Wang, Xiyin; Wicker, Thomas; Bharti, Arvind K.; Chapman, Jarrod; Feltus, F. Alex; Gowik, Udo; Grigoriev, Igor V.; Lyons, Eric; Maher, Christopher A.; Martis, Mihaela; Narechania, Apurva; Otillar, Robert P.; Penning, Bryan W.; Salamov, Asaf A.; Wang, Yu; Zhang, Lifang; Carpita, Nicholas C.; Freeling, Michael; Gingle, Alan R.; Hash, C. Thomas; Keller, Beat; Klein, Patricia; Kresovich, Stephen; McCann, Maureen C.; Ming, Ray; Peterson, Daniel G.; Mehboob-ur-Rahman; Ware, Doreen; Westhoff, Peter; Mayer, Klaus F. X.; Messing, Joachim; Rokhsar, Daniel S. (2009). "The Sorghum bicolor genome and the diversification of grasses". Nature. 457 (7229): 551–556. Bibcode:2009Natur.457..551P. doi: 10.1038/nature07723 . ISSN   1476-4687. PMID   19189423. S2CID   4382410.
  77. ↑ Schnable, Patrick S.; et al. (2009-11-20). "The B73 maize genome: Complexity, diversity, and dynamics". Science. 326 (5956): 1112–1115. Bibcode:2009Sci...326.1112S. doi:10.1126/science.1178534. PMID   19965430. S2CID   21433160 . Retrieved 2021-10-01.
  78. ↑ Tuskan GA, Difazio S, Jansson S, Bohlmann J, Grigoriev I, Hellsten U, et al. (September 2006). "The genome of black cottonwood, Populus trichocarpa (Torr. & Gray)". Science. 313 (5793): 1596–604. Bibcode:2006Sci...313.1596T. doi:10.1126/science.1128691. PMID   16973872. S2CID   7717980.
  79. ↑ Vogel, John P.; et al. (2010). "Genome sequencing and analysis of the model grass Brachypodium distachyon". Nature. 463 (7282): 763–768. Bibcode:2010Natur.463..763T. doi: 10.1038/nature08747 . ISSN   1476-4687. PMID   20148030. S2CID   4367075.
  80. ↑ "Plant Flagship Genomes". DOE Joint Genome Institute. Retrieved 2022-02-10.
  81. ↑ Ausubel, Frederick M. (2014-10-01). "Twists and Turns: My Career Path and Concerns About the Future". Genetics. 198 (2): 431–434. doi:10.1534/genetics.114.169102. ISSN   0016-6731. PMC   4196596 . PMID   25316778 . Retrieved 2017-10-22.
  82. ↑ "Elliot Meyerowitz Christopher Somerville - Balzan Prize Plant Molecular Genetics". Milano Zurigo. Retrieved December 20, 2017.
  83. ↑ "2011 Plant Science Program HHMI-GBMF Investigators". HHMI. Retrieved 2021-07-02.
  84. ↑ "New Program Boosts Support for Plant Scientists at Critical Time". HHMI. Retrieved 2021-07-02.
  85. ↑ Gutman, Benjamin L.; Niyogi, Krishna K. (2004-06-01). "Chlamydomonas and Arabidopsis. A Dynamic Duo". Plant Physiology. 135 (2): 607–610. doi:10.1104/pp.104.041491. ISSN   0032-0889. PMC   514095 . PMID   15208408 . Retrieved 2021-07-02.
  86. ↑ "Joanne Chory". HHMI. Retrieved 2021-07-02.
  87. ↑ "Breakthrough Prize – Life Sciences Breakthrough Prize Laureates – Joanne Chory" . Retrieved 2023-08-26.
  88. ↑ "Daphne Preuss". HHMI. Retrieved 2021-07-02.
  89. ↑ "Steven E. Jacobsen". HHMI. Retrieved 2021-07-02.
  90. ↑ "Caroline Dean". Wolf Foundation. 2020-01-13. Retrieved 2023-09-13.[ permanent dead link ]
  91. ↑ Schneeberger, Korbinian (2014). "Using next-generation sequencing to isolate mutant genes from forward genetic screens". Nature Reviews Genetics. 15 (10): 662–676. doi:10.1038/nrg3745. hdl: 11858/00-001M-0000-0024-CF80-4 . ISSN   1471-0056. PMID   25139187. S2CID   1822657.
  92. ↑ Li, Jian-Feng; Norville, Julie E.; Aach, John; McCormack, Matthew; Zhang, Dandan; Bush, Jenifer; Church, George M.; Sheen, Jen (2013). "Multiplex and homologous recombination-mediated genome editing in Arabidopsis and Nicotiana benthamiana using guide RNA and Cas9". Nature Biotechnology. 31 (8): 688–691. doi:10.1038/nbt.2654. ISSN   1087-0156. PMC   4078740 . PMID   23929339.
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