Melarsomine

Melarsomine

Clinical data
Trade names	Immiticide, Diroban
AHFS/Drugs.com	International Drug Names
ATC code	none
Identifiers
IUPAC name Bis(2-aminoethyl) {4-[(4,6-diamino-1,3,5-triazin-2-yl)amino]phenyl}arsonodithioite
CAS Number	128470-15-5
PubChem CID	65962
ChemSpider	59365
UNII	374GJ0S41A
KEGG	D08168  Y
CompTox Dashboard (EPA)	DTXSID40155907
Chemical and physical data
Formula	C13H21AsN8S2
Molar mass	428.41 g·mol−1
3D model (JSmol)	Interactive image
SMILES C1=CC(=CC=C1NC2=NC(=NC(=N2)N)N)[As](SCCN)SCCN
InChI InChI=1S/C13H21AsN8S2/c15-5-7-23-14(24-8-6-16)9-1-3-10(4-2-9)19-13-21-11(17)20-12(18)22-13/h1-4H,5-8,15-16H2,(H5,17,18,19,20,21,22) Key:MGEOLZFMLHYCFZ-UHFFFAOYSA-N
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Melarsomine (melaminylthioarsenate) is an arsenic-based anthelmintic. In the U.S., it is marketed under the trade names Immiticide (Merial) and Diroban (Zoetis), and is approved by the FDA's Center for Veterinary Medicine for the treatment of adult heartworm (Dirofilaria immitis) infection in dogs. It is not approved for treatment in cats, or dogs in late-stage infection. ^{[1] [2]}

References

1. Tilley LP (2008). Manual of Canine and Feline Cardiology. Elsevier Health Sciences. pp. 194–197. ISBN   978-1-4160-2398-2.
2. Bonagura JD, Twedt DC (2013). Kirk's Current Veterinary Therapy XV. Elsevier Health Sciences. p. 2502. ISBN   978-0-323-22762-9.

External links

• American Heartworm Society