Morten Kringelbach

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Morten L Kringelbach
Born
Nationality Danish
AwardsScience Communication Prize 2006, Danish Ministry of Higher Education and Science. [1]
Scientific career
Fields Neuroscience, Cognitive Science
Institutions University of Oxford, University of Aarhus
Website hedonia.kringelbach.org

Morten L Kringelbach is a professor of neuroscience at University of Oxford, UK and Aarhus University, Denmark. [2] [3] He is the director of the Centre for Eudaimonia and Human Flourishing, fellow of Linacre College, Oxford and board member of the Empathy Museum. [4]

Contents

Research overview

Kringelbach has made contributions to a range of topics within neuroscience using neuroimaging, deep brain stimulation and whole-brain modelling. His research is focused on reverse-engineering the human brain and in particular he has identified some of the evolutionary principles and heuristics of teleological computation enabling us to survive and thrive, which depend on intact human brain systems related to emotion, pleasure and eudaimonia.[ citation needed ] Together with Kent Berridge he has identified brain mechanisms underlying the reward system and identified a network of hedonic hotspots essential for the fundamental pleasure cycle of 'wanting', 'liking' and learning. [5] [6] In a large series of neuroimaging studies of many rewards, he has elucidated the spatiotemporal organisation of the orbitofrontal cortex, [7] for example, demonstrating a fast parental signature of infant cuteness even in adults who are not yet parents. [8] [9] [10] Kringelbach and Berridge have also investigated the close links between pleasure and happiness. [11]

Kringelbach has also worked with neurosurgeon Tipu Aziz to elucidate the neural mechanisms of deep brain stimulation for Parkinson's disease, essential tremor, dystonia and chronic pain [12]

Together with Peter Vuust, he founded the 'Center for Music in the Brain' [13] at University of Aarhus focused on better understanding the neuroscience of music and in particular the dual questions of how music is processed in the brain and how this can inform our understanding of fundamental principles behind brain functioning in general.

Furthermore, Kringelbach and Gustavo Deco have developed a research programme of whole-brain modelling for combining structural connectivity data Diffusion Tensor Imaging with functional neuroimaging data such as fMRI and magnetoencephalography. This allows for the discovery of causal mechanisms of brain function, and they have e.g. identified fundamental mechanisms and principles of integration and segregation, [14] as well as metastability and coherence. [15] In time, these findings might help open up for a better understanding and potential treatment of neuropsychiatric disorders [16] as well as the role of one of the cardinal symptoms, namely anhedonia, the lack of pleasure. [17]

See also

References

  1. "Forskningskommunikationsprisen — Uddannelses- og Forskningsministeriet".
  2. Theils, Lone (26 September 2008). "Professor i Nydelse". Berlingske Tidende. Retrieved 17 April 2018.
  3. Feltman, Rachel (8 June 2016). "The sneaky ways babies get inside our heads". Washington Post. Retrieved 17 April 2018.
  4. "Empathy Museum".
  5. Grayling, A.C. (27 November 2010). "Exchanges at the Frontier: Episode 5 Interview with Morten L Kringelbach". BBC World Service. Retrieved 17 April 2018.
  6. Berridge KC, Kringelbach ML (May 2015). "Pleasure systems in the brain". Neuron. 86 (3): 646–664. doi:10.1016/j.neuron.2015.02.018. PMC   4425246 . PMID   25950633.
  7. Kringelbach, Morten L. (2005). "The human orbitofrontal cortex: linking reward to hedonic experience". Nature Reviews Neuroscience. 6 (9): 691–702. doi:10.1038/nrn1747. ISSN   1471-003X. PMID   16136173. S2CID   205500365.
  8. Cunningham, Aimeel (1 April 2008). "Baby in the Brain". Scientific American. Retrieved 17 April 2018.
  9. Kringelbach, Morten L.; Lehtonen, Annukka; Squire, Sarah; Harvey, Allison G.; Craske, Michelle G.; Holliday, Ian E.; Green, Alexander L.; Aziz, Tipu Z.; Hansen, Peter C.; Cornelissen, Piers L.; Stein, Alan (2008). "A Specific and Rapid Neural Signature for Parental Instinct". PLOS ONE. 3 (2) e1664. Bibcode:2008PLoSO...3.1664K. doi: 10.1371/journal.pone.0001664 . ISSN   1932-6203. PMC   2244707 . PMID   18301742.
  10. Kringelbach, Morten L.; Stark, Eloise A.; Alexander, Catherine; Bornstein, Marc H.; Stein, Alan (2016). "On Cuteness: Unlocking the Parental Brain and Beyond". Trends in Cognitive Sciences. 20 (7): 545–558. doi:10.1016/j.tics.2016.05.003. ISSN   1364-6613. PMC   4956347 . PMID   27211583.
  11. Kringelbach ML, Berridge KC (2009). "Towards a functional neuroanatomy of pleasure and happiness". Trends in Cognitive Sciences. 13 (11): 479–487. doi:10.1016/j.tics.2009.08.006. PMC   2767390 . PMID   19782634.
  12. Kringelbach, Morten L.; Jenkinson, Ned; Owen, Sarah L.F.; Aziz, Tipu Z. (2007). "Translational principles of deep brain stimulation". Nature Reviews Neuroscience. 8 (8): 623–635. doi:10.1038/nrn2196. ISSN   1471-003X. PMID   17637800. S2CID   147427108.
  13. "Center for Music in the Brain".
  14. Deco, Gustavo; Tononi, Giulio; Boly, Melanie; Kringelbach, Morten L. (2015). "Rethinking segregation and integration: contributions of whole-brain modelling". Nature Reviews Neuroscience. 16 (7): 430–439. doi:10.1038/nrn3963. hdl: 10230/27083 . ISSN   1471-003X. PMID   26081790. S2CID   7962033.
  15. Deco, Gustavo; Kringelbach, Morten (2016). "Metastability and Coherence: Extending the Communication through Coherence Hypothesis Using a Whole-Brain Computational Perspective". Trends in Neurosciences. 39 (6): 432. doi: 10.1016/j.tins.2016.04.006 . ISSN   0166-2236. PMID   27131472.
  16. Deco, Gustavo; Kringelbach, Morten L. (2014). "Great Expectations: Using Whole-Brain Computational Connectomics for Understanding Neuropsychiatric Disorders". Neuron. 84 (5): 892–905. doi: 10.1016/j.neuron.2014.08.034 . ISSN   0896-6273. PMID   25475184.
  17. Roemer Thomsen, Kristine; Whybrow, Peter C.; Kringelbach, Morten L. (2015). "Reconceptualizing anhedonia: novel perspectives on balancing the pleasure networks in the human brain". Frontiers in Behavioral Neuroscience. 9: 49. doi: 10.3389/fnbeh.2015.00049 . ISSN   1662-5153. PMC   4356228 . PMID   25814941.

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