NAT5

NAA20
Identifiers
Aliases	NAA20 , NAT3, NAT3P, NAT5, NAT5P, dJ1002M8.1, N(alpha)-acetyltransferase 20, NatB catalytic subunit, N-alpha-acetyltransferase 20, NatB catalytic subunit, MRT73
External IDs	OMIM: 610833; MGI: 1915127; HomoloGene: 7165; GeneCards: NAA20; OMA:NAA20 - orthologs
Gene location (Human) Chr. Chromosome 20 (human) [1] Band 20p11.23 Start 20,017,310 bp [1] End 20,033,655 bp [1]
Gene location (Mouse) Chr. Chromosome 2 (mouse) [2] Band 2 G1|2 71.28 cM Start 145,744,019 bp [2] End 145,758,345 bp [2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in islet of Langerhans tibialis anterior muscle mucosa of pharynx gingival epithelium oral cavity skin of arm body of pancreas right testis deltoid muscle left testis Top expressed in heart quadriceps femoris muscle epiblast embryo neural tube right kidney mesencephalon ventricular zone lip thymus More reference expression data BioGPS n/a
Gene ontology Molecular function transferase activity acyltransferase activity peptide alpha-N-acetyltransferase activity Cellular component intracellular anatomical structure NatB complex cytosol nucleus cytoplasm Biological process N-terminal peptidyl-methionine acetylation Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 51126 67877 Ensembl ENSG00000173418 ENSMUSG00000002728 UniProt P61599 P61600 RefSeq (mRNA) NM_181528 NM_016100 NM_181527 NM_001141965 NM_026425 RefSeq (protein) NP_057184 NP_852668 NP_852669 NP_001135437 NP_080701 Location (UCSC) Chr 20: 20.02 – 20.03 Mb Chr 2: 145.74 – 145.76 Mb PubMed search [3] [4]
Wikidata
View/Edit Human View/Edit Mouse

N-terminal acetyltransferase B complex catalytic subunit NAT5 is an enzyme that in humans is encoded by the NAT5 gene. ^{[5] [6]}

References

1. GRCh38: Ensembl release 89: ENSG00000173418 – Ensembl, May 2017
2. GRCm38: Ensembl release 89: ENSMUSG00000002728 – Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. Sugiura N, Adams SM, Corriveau RA (Oct 2003). "An evolutionarily conserved N-terminal acetyltransferase complex associated with neuronal development". J Biol Chem. 278 (41): 40113–20. doi: 10.1074/jbc.M301218200 . PMID   12888564.
6. "Entrez Gene: NAT5 N-acetyltransferase 5".

Further reading

• Vitale N, Pacheco-Rodriguez G, Ferrans VJ, et al. (2000). "Specific functional interaction of human cytohesin-1 and ADP-ribosylation factor domain protein (ARD1)". J. Biol. Chem. 275 (28): 21331–9. doi: 10.1074/jbc.M909642199 . PMID   10748148.
• Hartley JL, Temple GF, Brasch MA (2001). "DNA Cloning Using In Vitro Site-Specific Recombination". Genome Res. 10 (11): 1788–95. doi:10.1101/gr.143000. PMC   310948 . PMID   11076863.
• Wiemann S, Weil B, Wellenreuther R, et al. (2001). "Toward a Catalog of Human Genes and Proteins: Sequencing and Analysis of 500 Novel Complete Protein Coding Human cDNAs". Genome Res. 11 (3): 422–35. doi:10.1101/gr.GR1547R. PMC   311072 . PMID   11230166.
• Simpson JC, Wellenreuther R, Poustka A, et al. (2001). "Systematic subcellular localization of novel proteins identified by large-scale cDNA sequencing". EMBO Rep. 1 (3): 287–92. doi:10.1093/embo-reports/kvd058. PMC   1083732 . PMID   11256614.
• Deloukas P, Matthews LH, Ashurst J, et al. (2002). "The DNA sequence and comparative analysis of human chromosome 20". Nature. 414 (6866): 865–71. Bibcode:2001Natur.414..865D. doi: 10.1038/414865a . PMID   11780052.
• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi: 10.1073/pnas.242603899 . PMC   139241 . PMID   12477932.
• Polevoda B, Cardillo TS, Doyle TC, et al. (2003). "Nat3p and Mdm20p are required for function of yeast NatB Nalpha-terminal acetyltransferase and of actin and tropomyosin". J. Biol. Chem. 278 (33): 30686–97. doi: 10.1074/jbc.M304690200 . PMID   12783868.
• Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC   528928 . PMID   15489334.
• Wiemann S, Arlt D, Huber W, et al. (2004). "From ORFeome to Biology: A Functional Genomics Pipeline". Genome Res. 14 (10B): 2136–44. doi:10.1101/gr.2576704. PMC   528930 . PMID   15489336.
• Mehrle A, Rosenfelder H, Schupp I, et al. (2006). "The LIFEdb database in 2006". Nucleic Acids Res. 34 (Database issue): D415–8. doi:10.1093/nar/gkj139. PMC   1347501 . PMID   16381901.
• Arnesen T, Anderson D, Torsvik J, et al. (2006). "Cloning and characterization of hNAT5/hSAN: an evolutionarily conserved component of the NatA protein N-alpha-acetyltransferase complex". Gene. 371 (2): 291–5. doi:10.1016/j.gene.2005.12.008. PMID   16507339.
• Sánchez-Puig N, Fersht AR (2006). "Characterization of the native and fibrillar conformation of the human Nα-acetyltransferase ARD1". Protein Sci. 15 (8): 1968–76. doi:10.1110/ps.062264006. PMC   2242591 . PMID   16823041.