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Other names | (4S)-4-methyl-salinomycin |
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ECHA InfoCard | 100.122.892 |
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Formula | C43H72O11 |
Molar mass | 765.038 g·mol−1 |
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Narasin is a coccidiostat and antibacterial agent. [1] [2] It is a derivative of salinomycin with an additional methyl group. Narasin is produced by fermentation of a strain of Streptomyces aureofaciens . [3]
Coccidia (Coccidiasina) are a subclass of microscopic, spore-forming, single-celled obligate intracellular parasites belonging to the apicomplexan class Conoidasida. As obligate intracellular parasites, they must live and reproduce within an animal cell. Coccidian parasites infect the intestinal tracts of animals, and are the largest group of apicomplexan protozoa.
Furazolidone is a nitrofuran antibacterial agent and monoamine oxidase inhibitor (MAOI). It is marketed by Roberts Laboratories under the brand name Furoxone and by GlaxoSmithKline as Dependal-M.
Coccidiosis is a parasitic disease of the intestinal tract of animals caused by coccidian protozoa. The disease spreads from one animal to another by contact with infected feces or ingestion of infected tissue. Diarrhea, which may become bloody in severe cases, is the primary symptom. Most animals infected with coccidia are asymptomatic, but young or immunocompromised animals may suffer severe symptoms and death.
Eimeria is a genus of apicomplexan parasites that includes various species capable of causing the disease coccidiosis in animals such as cattle, poultry and smaller ruminants including sheep and goats. Eimeria species are considered to be monoxenous because the life cycle is completed within a single host, and stenoxenous because they tend to be host specific, although a number of exceptions have been identified. Species of this genus infect a wide variety of hosts. Thirty-one species are known to occur in bats (Chiroptera), two in turtles, and 130 named species infect fish. Two species infect seals. Five species infect llamas and alpacas: E. alpacae, E. ivitaensis, E. lamae, E. macusaniensis, and E. punonensis. A number of species infect rodents, including E. couesii, E. kinsellai, E. palustris, E. ojastii and E. oryzomysi. Others infect poultry, rabbits and cattle. For full species list, see below.
Sodium bisulfate, also known as sodium hydrogen sulfate, is the sodium salt of the bisulfate anion, with the molecular formula NaHSO4. Sodium bisulfate is an acid salt formed by partial neutralization of sulfuric acid by an equivalent of sodium base, typically in the form of either sodium hydroxide (lye) or sodium chloride (table salt). It is a dry granular product that can be safely shipped and stored. The anhydrous form is hygroscopic. Solutions of sodium bisulfate are acidic, with a 1M solution having a pH of slightly below 1.
The dwarf musk deer or Chinese forest musk deer is an artiodactyl native to southern and central China and northernmost Vietnam. The species name is after the collector Mikhail Mikhailovich Berezovsky. On June 14, 1976, China entered the dwarf musk deer onto its endangered species list. Four subspecies are recognized:
The Eucoccidiorida are an order of microscopic, spore-forming, single-celled parasites belonging to the apicomplexan class Conoidasida. Protozoans of this order include parasites of humans, and both domesticated and wild animals including birds. Among these parasites are the Toxoplasma gondii that cause toxoplasmosis and Isospora belli, which results in isosporiasis.
Amprolium is the organic compound sold as a coccidiostat used in poultry. It has many International Nonproprietary Names.
Arprinocid is a coccidiostat used in veterinary medicine.
Decoquinate is a quinolone coccidiostat used in veterinary medicine.
Diclazuril is a coccidiostat.
Ethopabate is a coccidiostat used in poultry.
Salinomycin is an antibacterial and coccidiostat ionophore therapeutic drug.
Eimeriorina is a suborder of phylum Apicomplexa.
A feed additive is an additive of extra nutrient or drug for livestock. Such additives include vitamins, amino acids, fatty acids, minerals, pharmaceutical, fungal products and steroidal compounds. The additives might impact feed presentation, hygiene, digestibility, or effect on intestinal health.
Febrifugine is a quinazolinone alkaloid first isolated from the Chinese herb Dichroa febrifuga, but also found in the garden plant Hydrangea. Laboratory synthesis of febrifugine determined that the originally reported stereochemistry was incorrect.
Growell India is a multinational feed additive company headquartered in Pune, Maharashtra, India. Growell India manufactures and exports phytogenic feed additives for livestock. The company is a pioneer in phytogenic feed additives and has established a strong presence worldwide since its inception in 1995.
Eimeria zuernii is a species of the parasite Eimeria that causes diarrheic disease known as eimeriosis in cattle, and mainly affects younger animals. The disease is also commonly referred to as coccidiosis. The parasite can be found in cattle around the globe.
Eimeria arlongi is a species of Eimeria that causes clinical coccidiosis in goats. It and Eimeria ninakohlyakimovae are two of the most pathogenic species for goats. It is particularly prevalent in goat kids in Iran. Issues with coccidiosis specifically due to Eimeria arloingi have also been reported in Egypt and Portugal. It is unclear whether this species is present in the Americas as most of the case reports of coccidiosis in these areas do not differentiate the species causing the disease. Infections with this species are commonly compounded by infections with other Eimeria species in "mixed infections." This species is closely related to Eimeria bovis and Eimeria zuernii which are both highly pathogenic in cattle' Infections with this species are characterized by lesions specifically in the jejunum, but also the ilium and cecum which results in diarrhea. Oocysts begin shedding between 16 and 18 days after the animal is infected which is when the parasite is spread. The shedding can last as long as 15 days. This parasite causes an immune response in its host that includes accumulation of fluid in body cavities, presence of large numbers of leukocytes in the small intestine, and necrosis of the tissue of the small intestine. Pale yellow plaques can be seen on the small intestine of severely affected kids at necropsy.
Eimeria bovis is a parasite belonging to the genus Eimeria and is found globally. The pathogen can cause a diarrheic disease in cattle referred to as either eimeriosis or coccidiosis. The infection predominantly cause disease in younger animals.