NeuroNation

Last updated
NeuroNation
NeuroNation logo.png
Type of site
cognitive training
Available inGerman, English, Spanish, Portuguese, Italian, Russian, French, Polish, Korean, Japanese
Headquarters Berlin, Germany
Created byRojahn Ahmadi and Jakob Futorjanski
URL www.neuronation.com
Commercialyes
Users 10 million
Launched2011

NeuroNation and its associated medical app NeuroNation MED are cognitive training software applications developed by the German healthcare technology company Synaptikon GmbH. [1] [2] [3] NeuroNation was launched in 2011. [4]

Contents

Platform

The online platform was launched in 2011, and initially served Germany, Austria, and Switzerland. [5] In 2014, Der Spiegel and XLHealth AG bought a 25% stake in NeuroNation, financing an expansion into English, French, Spanish, Italian, Russian, Japanese, and Portuguese markets. [5]

NeuroNation is a multi-modal cognitive training application for prevention of neurodegenerative diseases and cognitive enhancement. [6] [7]

Its use is reimbursed by several German health insurers, including Deutsche BKK. [8] While the NeuroNation app and similar ones are heavily advertised with claims of improving general cognitive function, there is no evidence to show that NeuroNation or similar programs do so; at most they improve performance in the training tasks given in the program. [9] [10]

The program began with a single-payment model, later shifting to a subscription business model. [11] The app offers some content free, while other activities are available through in-app purchases. [12]

Scientific research

In the "Intera-KT" project, NeuroNation collaborated  with the Berlin University Hospital Charité and other partners to digitise paper-based cognitive tests. [13]

NeuroNation is currently participating in a study on the effects of independent cognitive training using Neuronation MED on patients with mild cognitive disorders and patients with Post COVID-19 condition. [14]

In several studies, healthy participants who have used NeuroNation as a cognitive training tool have shown positive effects for working memory, memory, and executive functions. [15] [16] [17] One study by MSH Medical School Hamburg and the University of Würzburg observed that subjects who participated in NeuroNation exercises exhibited improved memory, concentration, and general well-being. [15]

Related Research Articles

<span class="mw-page-title-main">Working memory</span> Cognitive system for temporarily holding information

Working memory is a cognitive system with a limited capacity that can hold information temporarily. It is important for reasoning and the guidance of decision-making and behavior. Working memory is often used synonymously with short-term memory, but some theorists consider the two forms of memory distinct, assuming that working memory allows for the manipulation of stored information, whereas short-term memory only refers to the short-term storage of information. Working memory is a theoretical concept central to cognitive psychology, neuropsychology, and neuroscience.

<span class="mw-page-title-main">Cognitive neuroscience</span> Scientific field

Cognitive neuroscience is the scientific field that is concerned with the study of the biological processes and aspects that underlie cognition, with a specific focus on the neural connections in the brain which are involved in mental processes. It addresses the questions of how cognitive activities are affected or controlled by neural circuits in the brain. Cognitive neuroscience is a branch of both neuroscience and psychology, overlapping with disciplines such as behavioral neuroscience, cognitive psychology, physiological psychology and affective neuroscience. Cognitive neuroscience relies upon theories in cognitive science coupled with evidence from neurobiology, and computational modeling.

<span class="mw-page-title-main">Caudate nucleus</span> Structure of the striatum in the basal ganglia of the brain

The caudate nucleus is one of the structures that make up the corpus striatum, which is a component of the basal ganglia in the human brain. While the caudate nucleus has long been associated with motor processes due to its role in Parkinson's disease, it plays important roles in various other nonmotor functions as well, including procedural learning, associative learning and inhibitory control of action, among other functions. The caudate is also one of the brain structures which compose the reward system and functions as part of the cortico–basal ganglia–thalamic loop.

<span class="mw-page-title-main">Nootropic</span> Compound intended to improve cognitive function

Nootropics, colloquially brain supplements, smart drugs and cognitive enhancers, are natural, semisynthetic or synthetic compounds which purportedly improve cognitive functions, such as executive functions, attention or memory.

The concepts of fluid intelligence (gf) and crystallized intelligence (gc) were introduced in 1963 by the psychologist Raymond Cattell. According to Cattell's psychometrically-based theory, general intelligence (g) is subdivided into gf and gc. Fluid intelligence is the ability to solve novel reasoning problems and is correlated with a number of important skills such as comprehension, problem-solving, and learning. Crystallized intelligence, on the other hand, involves the ability to deduce secondary relational abstractions by applying previously learned primary relational abstractions.

Neuroplasticity, also known as neural plasticity or brain plasticity, is the ability of neural networks in the brain to change through growth and reorganization. It is when the brain is rewired to function in some way that differs from how it previously functioned. These changes range from individual neuron pathways making new connections, to systematic adjustments like cortical remapping or neural oscillation. Other forms of neuroplasticity include homologous area adaptation, cross modal reassignment, map expansion, and compensatory masquerade. Examples of neuroplasticity include circuit and network changes that result from learning a new ability, information acquisition, environmental influences, pregnancy, caloric intake, practice/training, and psychological stress.

<span class="mw-page-title-main">Memory and aging</span> Aspect of senescence

Age-related memory loss, sometimes described as "normal aging", is qualitatively different from memory loss associated with types of dementia such as Alzheimer's disease, and is believed to have a different brain mechanism.

Cognitive reserve is the mind's and brain's resistance to damage of the brain. The mind's resilience is evaluated behaviorally, whereas the neuropathological damage is evaluated histologically, although damage may be estimated using blood-based markers and imaging methods. There are two models that can be used when exploring the concept of "reserve": brain reserve and cognitive reserve. These terms, albeit often used interchangeably in the literature, provide a useful way of discussing the models. Using a computer analogy, brain reserve can be seen as hardware and cognitive reserve as software. All these factors are currently believed to contribute to global reserve. Cognitive reserve is commonly used to refer to both brain and cognitive reserves in the literature.

<span class="mw-page-title-main">Transcranial direct-current stimulation</span> Technique of brain electric stimulation therapy

Transcranial direct current stimulation (tDCS) is a form of neuromodulation that uses constant, low direct current delivered via electrodes on the head. It was originally developed to help patients with brain injuries or neuropsychiatric conditions such as major depressive disorder. It can be contrasted with cranial electrotherapy stimulation, which generally uses alternating current the same way, as well as transcranial magnetic stimulation.

Post-chemotherapy cognitive impairment (PCCI) describes the cognitive impairment that can result from chemotherapy treatment. While there is no concrete statistic for the number of patients that experience some level of post-chemotherapy cognitive impairment, the estimated percentage is between 13 and 70 percent of patients. The phenomenon first came to light because of the large number of breast cancer survivors who complained of changes in memory, fluency, and other cognitive abilities that impeded their ability to function as they had pre-chemotherapy.

Certain treatments for childhood cancer are known to cause learning problems in survivors, particularly when central nervous system (CNS)-directed therapies are used. As the mortality rates of childhood cancers have plummeted since effective treatment regiments have been introduced, greater attention has been paid to the effect of treatment on neurocognitive morbidity and quality of life of survivors. The goal of treatment for childhood cancers today is to minimize these adverse "late effects", while ensuring long-term survival.

Post-traumatic amnesia (PTA) is a state of confusion that occurs immediately following a traumatic brain injury (TBI) in which the injured person is disoriented and unable to remember events that occur after the injury. The person may be unable to state their name, where they are, and what time it is. When continuous memory returns, PTA is considered to have resolved. While PTA lasts, new events cannot be stored in the memory. About a third of patients with mild head injury are reported to have "islands of memory", in which the patient can recall only some events. During PTA, the patient's consciousness is "clouded". Because PTA involves confusion in addition to the memory loss typical of amnesia, the term "post-traumatic confusional state" has been proposed as an alternative.

The n-back task is a continuous performance task that is commonly used as an assessment in psychology and cognitive neuroscience to measure a part of working memory and working memory capacity. The n-back was introduced by Wayne Kirchner in 1958. N-Back games are purported to be a training method to improve working memory and working memory capacity and also increase fluid intelligence. While some scientific studies have shown such a connection, others have not.

The early left anterior negativity is an event-related potential in electroencephalography (EEG), or component of brain activity that occurs in response to a certain kind of stimulus. It is characterized by a negative-going wave that peaks around 200 milliseconds or less after the onset of a stimulus, and most often occurs in response to linguistic stimuli that violate word-category or phrase structure rules. As such, it is frequently a topic of study in neurolinguistics experiments, specifically in areas such as sentence processing. While it is frequently used in language research, there is no evidence yet that it is necessarily a language-specific phenomenon.

<span class="mw-page-title-main">Cogmed</span> Cognitive training software program

Cogmed is a cognitive training software program created in the lab of Torkel Klingberg, a neuroscientist at the Karolinska Institute. Torkel Klingberg was using it to present working memory challenges to people while he studied their brains using fMRI, to try to learn about neuroplasticity. When the studies appeared to show that the challenges improved working memory, Klingberg founded Cogmed in 2001, with financial backing from the Karolinska Institute and venture capitalists.

<span class="mw-page-title-main">Memory improvement</span> Act of improving ones memory

Memory improvement is the act of enhancing one's memory. Research on improving memory is driven by amnesia, age-related memory loss, and people’s desire to enhance their memory. Research involved in memory improvement has also worked to determine what factors influence memory and cognition. There are many different techniques to improve memory some of which include cognitive training, psychopharmacology, diet, stress management, and exercise. Each technique can improve memory in different ways.

In psychology, confabulation is a memory error consisting of the production of fabricated, distorted, or misinterpreted memories about oneself or the world. It is generally associated with certain types of brain damage or a specific subset of dementias. While still an area of ongoing research, the basal forebrain is implicated in the phenomenon of confabulation. People who confabulate present with incorrect memories ranging from subtle inaccuracies to surreal fabrications, and may include confusion or distortion in the temporal framing of memories. In general, they are very confident about their recollections, even when challenged with contradictory evidence.

For patients with Alzheimer's disease, music therapy provides a beneficial interaction between a patient and an individualized musical regimen and has been shown to increase cognition and slow the deterioration of memory loss. Music therapy is a clinical and evidence-based intervention that involves music in some capacity and includes both a participant and a music therapist who have completed an accredited music therapy program.

Neuroenhancement or cognitive enhancement is the experimental use of pharmacological or non-pharmacological methods intended to improve cognitive and affective abilities in healthy people who do not have a mental illness. Agents or methods of neuroenhancement are intended to affect cognitive, social, psychological, mood, or motor benefits beyond normal functioning.

NeuroIntegration Therapy (NIT) is a non-invasive combination therapy that integrates quantitative electroencephalography (qEEG or QEEG) brain mapping with additional therapies such as neurofeedback, vibroacoustic therapy, pulsed electromagnetic field therapy (PEMFT, or PEMF therapy) and photic stimulation (light therapy.)

References

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  2. "Effectiveness of a mobile application for independent cognitive training in patients with mild cognitive impairments: Study protocol for the NeNaE Study, a randomized controlled trial". www.researchsquare.com. 2023-09-28. Retrieved 2024-01-26.
  3. Maas, Marie-Charlotte (18 March 2015). "Senioren-Start-ups: Alt, aber oho - WiWo Gründer". WiWo Gründer (in German).
  4. "Spiegel picks up stake in Berlin brain-training startup NeuroNation". Venture Capital Post. 2014-01-24. Retrieved 2024-01-26.
  5. 1 2 "Spiegel picks up stake in Berlin brain-training startup NeuroNation". Venture Capital Post. 24 January 2014.
  6. Walton, Courtney Campbell; Lampit, Amit; Boulamatsis, Christos; Hallock, Harry; Barr, Polly; Ginige, Jeewani Anupama; Brodaty, Henry; Chau, Tiffany; Heffernan, Megan; Sachdev, Perminder Singh; Singh, Maria A. Fiatarone; Valenzuela, Michael (2019-02-27). "Design and Development of the Brain Training System for the Digital "Maintain Your Brain" Dementia Prevention Trial". JMIR Aging. 2 (1): e13135. doi: 10.2196/13135 . hdl: 11343/238738 . PMC   6715098 . PMID   31518277.
  7. Bryson, Steve (2022-08-12). "Early Parkinson's Cases May Benefit From NeuroNation Brain Training App | Parkinson's News Today". parkinsonsnewstoday.com. Retrieved 2024-01-26.
  8. "Schlaganfall: Kasse zahlt erstmals Digital-Health-Anwendung". Ärzte Zeitung (in German). 26 August 2014.
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  12. NeuroNation, Bangkok Post, 2014
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