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Vaccination is the administration of a vaccine to help the immune system develop immunity from a disease. Vaccines contain a microorganism or virus in a weakened, live or killed state, or proteins or toxins from the organism. In stimulating the body's adaptive immunity, they help prevent sickness from an infectious disease. When a sufficiently large percentage of a population has been vaccinated, herd immunity results. Herd immunity protects those who may be immunocompromised and cannot get a vaccine because even a weakened version would harm them. The effectiveness of vaccination has been widely studied and verified. Vaccination is the most effective method of preventing infectious diseases; widespread immunity due to vaccination is largely responsible for the worldwide eradication of smallpox and the elimination of diseases such as polio and tetanus from much of the world. However, some diseases, such as measles outbreaks in America, have seen rising cases due to relatively low vaccination rates in the 2010s – attributed, in part, to vaccine hesitancy. According to the World Health Organization, vaccination prevents 3.5–5 million deaths per year.
Measles is a highly contagious, vaccine-preventable infectious disease caused by measles virus. Symptoms usually develop 10–12 days after exposure to an infected person and last 7–10 days. Initial symptoms typically include fever, often greater than 40 °C (104 °F), cough, runny nose, and inflamed eyes. Small white spots known as Koplik's spots may form inside the mouth two or three days after the start of symptoms. A red, flat rash which usually starts on the face and then spreads to the rest of the body typically begins three to five days after the start of symptoms. Common complications include diarrhea, middle ear infection (7%), and pneumonia (6%). These occur in part due to measles-induced immunosuppression. Less commonly seizures, blindness, or inflammation of the brain may occur. Other names include morbilli, rubeola, red measles, and English measles. Both rubella, also known as German measles, and roseola are different diseases caused by unrelated viruses.
Herd immunity is a form of indirect protection that applies only to contagious diseases. It occurs when a sufficient percentage of a population has become immune to an infection, whether through previous infections or vaccination, thereby reducing the likelihood of infection for individuals who lack immunity.
Immunization, or immunisation, is the process by which an individual's immune system becomes fortified against an infectious agent.
Vaccine hesitancy is a delay in acceptance, or refusal, of vaccines despite the availability of vaccine services and supporting evidence. The term covers refusals to vaccinate, delaying vaccines, accepting vaccines but remaining uncertain about their use, or using certain vaccines but not others. Although adverse effects associated with vaccines are occasionally observed, the scientific consensus that vaccines are generally safe and effective is overwhelming. Vaccine hesitancy often results in disease outbreaks and deaths from vaccine-preventable diseases. Therefore, the World Health Organization characterizes vaccine hesitancy as one of the top ten global health threats.
The schedule for childhood immunizations in the United States is published by the Centers for Disease Control and Prevention (CDC). The vaccination schedule is broken down by age: birth to six years of age, seven to eighteen, and adults nineteen and older. Childhood immunizations are key in preventing diseases with epidemic potential.
Pneumococcal conjugate vaccine is a pneumococcal vaccine made with the conjugate vaccine method and used to protect infants, young children, and adults against disease caused by the bacterium Streptococcus pneumoniae (pneumococcus). It contains purified capsular polysaccharide of pneumococcal serotypes conjugated to a carrier protein to improve antibody response compared to the pneumococcal polysaccharide vaccine. The World Health Organization (WHO) recommends the use of the conjugate vaccine in routine immunizations given to children.
Pneumococcal vaccines are vaccines against the bacterium Streptococcus pneumoniae. Their use can prevent some cases of pneumonia, meningitis, and sepsis. There are two types of pneumococcal vaccines: conjugate vaccines and polysaccharide vaccines. They are given by injection either into a muscle or just under the skin.
The Expanded Program on Immunization(EPI) in the Philippines began in 1976 through Presidential Decree No. 996 signed by President Ferdinand Marcos. And, in 1986, made a response to the Universal Child Immunization goal. The four major strategies include:
- sustaining high routine Full Immunized Child (FIC) coverage of at least 90% in all provinces and cities;
- sustaining the polio-free country for global certification;
- eliminating measles by 2008; and
- eliminating neonatal tetanus by 2008.
Hepatitis B vaccine is a vaccine that prevents hepatitis B. The first dose is recommended within 24 hours of birth with either two or three more doses given after that. This includes those with poor immune function such as from HIV/AIDS and those born premature. It is also recommended that health-care workers be vaccinated. In healthy people, routine immunization results in more than 95% of people being protected.
A vaccination policy is a health policy adopted in order to prevent the spread of infectious disease. These policies are generally put into place by state or local governments, but may also be set by private facilities, such as workplaces or schools. Many policies have been developed and implemented since vaccines were first made widely available.
The Expanded Program on Immunization is a World Health Organization program with the goal to make vaccines available to all children.
Measles vaccine protects against becoming infected with measles. Nearly all of those who do not develop immunity after a single dose develop it after a second dose. When the rate of vaccination within a population is greater than 92%, outbreaks of measles typically no longer occur; however, they may occur again if the rate of vaccination decreases. The vaccine's effectiveness lasts many years. It is unclear if it becomes less effective over time. The vaccine may also protect against measles if given within a couple of days after exposure to measles.
In Ukraine, the Human Rights Measurement Initiative finds that country is fulfilling 79.4% of what they should be fulfilling for the right to health, based on their level on income.
Italy is known for its generally very good health system, and the life expectancy is 80 for males and 85 for females, placing the country 5th in the world for life expectancy, and low infant mortality. In comparison to other Western countries, Italy has a relatively low rate of adult obesity, as there are several health benefits of the Mediterranean diet. The proportion of daily smokers was 22% in 2012, down from 24.4% in 2000 but still slightly above the OECD average. Smoking in public places including bars, restaurants, night clubs and offices has been restricted to specially ventilated rooms since 2005.
The Vaccines for Children Program (VFC) is a federally funded program in the United States providing no-cost vaccines to children who lack health insurance or who otherwise cannot afford the cost of the vaccination. The VFC program was created by the Omnibus Budget Reconciliation Act of 1993 and is required to be a new entitlement of each state's Medicaid plan under section 1928 of the Social Security Act. The program was officially implemented in October 1994 and serves eligible children in all U.S. states, as well as the Commonwealth of Puerto Rico, the U.S. Virgin Islands, American Samoa, Guam, and the Commonwealth of the Northern Mariana Islands.
Universal Immunisation Programme (UIP) is a vaccination programme launched by the Government of India in 1985. It became a part of Child Survival and Safe Motherhood Programme in 1992 and is currently one of the key areas under the National Health Mission since 2005. The programme now consists of vaccination for 12 diseases- tuberculosis, diphtheria, pertussis, tetanus, poliomyelitis, measles, hepatitis B, rotaviral gastroenteritis, Japanese encephalitis, rubella, pneumonia and Pneumococcal diseases. Hepatitis B and Pneumococcal diseases were added to the UIP in 2007 and 2017 respectively. The cost of all the vaccines are borne entirely by the Government of India and is funded through taxes with a budget of ₹7,234 crore (US$870 million) in 2022 and the program covers all residents of India, including foreign residents.
World Immunization Week is a global public health campaign to raise awareness and increase rates of immunization against vaccine-preventable diseases around the world. It takes place each year during the last week of April.
Non-specific effects of vaccines are effects which go beyond the specific protective effects against the targeted diseases. Non-specific effects can be strongly beneficial by increasing protection against non-targeted infections. This has been shown with two live attenuated vaccines, BCG vaccine and measles vaccine, through multiple randomized controlled trials. Theoretically, non-specific effects of vaccines may be detrimental, increasing overall mortality despite providing protection against the target diseases. Although observational studies suggest that diphtheria-tetanus-pertussis vaccine (DTP) may be highly detrimental, these studies are at high risk of bias and have failed to replicate when conducted by independent groups.
Measles was declared eliminated from the United States in 2000 by the World Health Organization due to the success of vaccination efforts. However, it continues to be reintroduced by international travelers, and in recent years, anti-vaccination sentiment has allowed for the reemergence of measles outbreaks.
References
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- 1 2 "Our Top Charities". GiveWell. Retrieved 30 August 2024.
- ↑ "Our Team". New Incentives. Archived from the original on 2024-06-13. Retrieved 2024-08-30.
- ↑ "Why This Social Entrepreneur Is Paying African Women To Go To Free HIV Clinics". Forbes. Retrieved 24 March 2021.
- ↑ "New Incentives". Giving what we can. Retrieved 24 March 2021.
- ↑ "How it works". New Incentives. Retrieved 24 March 2021.
- ↑ "Demographic and Health Survey" (PDF). dhsprogram.com. National Population Commission. 2018.
- ↑ "Child Mortality Estimates". UN Inter-agency Group for Child Mortality Estimation. Retrieved 2024-08-30.
- ↑ Tan-Torres Edejer, Tessa; Aikins, Moses; Black, Robert; Wolfson, Lara; Hutubessy, Raymond; Evans, David B. (2005). "Cost effectiveness analysis of strategies for child health in developing countries". BMJ. 331 (7526): 1177. doi: 10.1136/bmj.38652.550278.7C . PMC 1285096 . PMID 16282378.
- ↑ "We use cash transfers to increase immunization rates in Nigeria 286,010". New Incentives. Retrieved 24 March 2021.
- ↑ "Våre anbefalte organisasjoner". Gieffektvit. Retrieved 24 March 2021.
- ↑ "New Incentives (Conditional Cash Transfers to Increase Infant Vaccination)". GiveWell. Retrieved 2024-08-30.
- ↑ "Impact evaluation of New Incentives | Final report" (PDF). IDinsight. 18 November 2020.