Evidence and education
There is scientific consensus that the capacity to synthesize nylonase most probably developed as a single-step mutation that survived because it improved the fitness of the bacteria possessing the mutation. This is seen as a good example of evolution through mutation and natural selection that has been observed as it occurs and could not have come about until the production of nylon by humans. [3] [4] [5] [6]
The discovery was first publicized by science education advocates like the National Center for Science Education, and New Mexicans for Science and Reason (NMSR) who stated that research refutes claims made by creationists and intelligent design proponents. [3] [4] The claims were that random mutation and natural selection can never add new information to a genome and that the odds against a useful new protein, such as an enzyme, arising through a process of random mutation would be prohibitively high. [7] [8]
Physicist Dave Thomas, the President of NMSR, noted that gene duplication and frame-shift mutations were powerful sources of random mutation. [4] In particular, in response to comments by creationists such as Don Batten, NMSR has stated that it was these mutations that gave rise to nylonase, even if the genes were part of a plasmid as suggested by Batten. [4]
Apologetics
Proponents of creationism, such as Answers in Genesis and Creation Ministries International, have cited horticulturalist and apologist Don Batten, pointing out that scientific research showed that the genes involved were on a plasmid, and claiming that the phenomenon is evidence that plasmids in bacteria are a designed feature, intended to allow bacteria to adapt easily to new food sources or cope with toxic chemicals. Batten wrote:
It seems clear that plasmids are designed features of bacteria that enable adaptation to new food sources or the degradation of toxins. The details of just how they do this remains to be elucidated. The results so far clearly suggest that these adaptations did not come about by chance mutations, but by some designed mechanism. [9]
However, NMSR pointed out that the gene duplication and frame-shift mutations that gave rise to nylonase were powerful sources of random mutation, whether or not the genes were part of a plasmid as suggested by Batten. [4] A posting at TalkOrigins Archive by Ian Musgrave asserted that bacteria carry many genes in plasmids, particularly those involved in xenobiotic handling or metabolic functions. Musgrave added that in Pseudomonas, most of the xenobiotic degradation genes are on plasmids. Therefore it is entirely likely that a xenobiotic handling enzyme will arise from mutations of xenobiotic handling genes. The fact that these genes are on plasmids does not invalidate the fact that they exist, and exist only in two strains of bacteria. Musgrave also criticized Batten for mis-stating the conclusions of some of the authors of the scientific literature on nylon-eating bacteria. [10]
MSNBC published an editorial from science writer Ker Than that stated that the evolution of the enzymes, known as nylonase, produced by nylon-eating bacteria was a compelling argument against the claim made by intelligent design proponents that specified complexity required an intelligent designer, since nylonase function was both specified and complex. [5] Theologian and intelligent design proponent William Dembski posted a response that questioned whether the genetic changes that produced nylonase were complex enough to be considered specified complexity. [11] Biology professor Ken Miller said that intelligent design proponents claim that we can't see either design or evolution taking place and that therefore, according to the design proponents, intelligent design and evolution are both just matters of faith or world view. He added that however, the evolution of the enzyme nylonase, which scientists were able to repeat in the lab with another strain of bacteria, is one of a number of cases that show that evolution can be observed as it occurs. [6]
Intelligent design (ID) is a pseudoscientific argument for the existence of God, presented by its proponents as "an evidence-based scientific theory about life's origins". Proponents claim that "certain features of the universe and of living things are best explained by an intelligent cause, not an undirected process such as natural selection." ID is a form of creationism that lacks empirical support and offers no testable or tenable hypotheses, and is therefore not science. The leading proponents of ID are associated with the Discovery Institute, a Christian, politically conservative think tank based in the United States.
Irreducible complexity (IC) is the argument that certain biological systems with multiple interacting parts would not function if one of the parts were removed, so supposedly could not have evolved by successive small modifications from earlier less complex systems through natural selection, which would need all intermediate precursor systems to have been fully functional. This negative argument is then complemented by the claim that the only alternative explanation is a "purposeful arrangement of parts" inferring design by an intelligent agent. Irreducible complexity has become central to the creationist concept of intelligent design (ID), but the concept of irreducible complexity has been rejected by the scientific community, which regards intelligent design as pseudoscience. Irreducible complexity and specified complexity, are the two main arguments used by intelligent-design proponents to support their version of the theological argument from design.
William Albert Dembski is an American mathematician, philosopher and theologian. He was a proponent of intelligent design (ID) pseudoscience, specifically the concept of specified complexity, and was a senior fellow of the Discovery Institute's Center for Science and Culture (CSC). On September 23, 2016, he officially retired from intelligent design, resigning all his "formal associations with the ID community, including [his] Discovery Institute fellowship of 20 years". A February 2021 interview in the CSC's blog Evolution News announced "his return to the intelligent design arena".
Michael Joseph Behe is an American biochemist and an advocate of the pseudoscientific principle of intelligent design (ID).
The argument from poor design, also known as the dysteleological argument, is an argument against the assumption of the existence of a creator God, based on the reasoning that any omnipotent and omnibenevolent deity or deities would not create organisms with the perceived suboptimal designs that occur in nature.
The intelligent design movement is a neo-creationist religious campaign for broad social, academic and political change to promote and support the pseudoscientific idea of intelligent design (ID), which asserts that "certain features of the universe and of living things are best explained by an intelligent cause, not an undirected process such as natural selection." Its chief activities are a campaign to promote public awareness of this concept, the lobbying of policymakers to include its teaching in high school science classes, and legal action, either to defend such teaching or to remove barriers otherwise preventing it. The movement arose out of the creation science movement in the United States, and is driven by a small group of proponents.
Specified complexity is a creationist argument introduced by William Dembski, used by advocates to promote the pseudoscience of intelligent design. According to Dembski, the concept can formalize a property that singles out patterns that are both specified and complex, where in Dembski's terminology, a specified pattern is one that admits short descriptions, whereas a complex pattern is one that is unlikely to occur by chance. Proponents of intelligent design use specified complexity as one of their two main arguments, alongside irreducible complexity.
The Wedge Strategy is a creationist political and social action plan authored by the Discovery Institute, the hub of the pseudoscientific intelligent design movement. The strategy was put forth in a Discovery Institute manifesto known as the Wedge Document. Its goal is to change American culture by shaping public policy to reflect politically conservative fundamentalist evangelical Protestant values. The wedge metaphor is attributed to Phillip E. Johnson and depicts a metal wedge splitting a log.
Of Pandas and People: The Central Question of Biological Origins is a controversial 1989 school-level supplementary textbook written by Percival Davis and Dean H. Kenyon, edited by Charles Thaxton and published by the Texas-based Foundation for Thought and Ethics (FTE). The textbook endorses the pseudoscientific concept of intelligent design – the argument that life shows evidence of being designed by an intelligent agent which is not named specifically in the book, although proponents understand that it refers to the Christian God. The overview chapter was written by young Earth creationist Nancy Pearcey. They present various polemical arguments against the scientific theory of evolution. Before publication, early drafts used cognates of "creationist". After the Edwards v. Aguillard Supreme Court ruling that creationism is religion and not science, these were changed to refer to "intelligent design". The second edition published in 1993 included a contribution written by Michael Behe.
An intelligent designer, also referred to as an intelligent agent, is the pseudoscientific hypothetical willed and self-aware entity that the intelligent design movement argues had some role in the origin and/or development of life. The term "intelligent cause" is also used, implying their teleological supposition of direction and purpose in features of the universe and of living things.
Neo-creationism is a pseudoscientific movement which aims to restate creationism in terms more likely to be well received by the public, by policy makers, by educators and by the scientific community. It aims to re-frame the debate over the origins of life in non-religious terms and without appeals to scripture. This comes in response to the 1987 ruling by the United States Supreme Court in Edwards v. Aguillard that creationism is an inherently religious concept and that advocating it as correct or accurate in public-school curricula violates the Establishment Clause of the First Amendment.
"A Scientific Dissent from Darwinism" was a statement issued in 2001 by the Discovery Institute, a Christian, conservative think tank based in Seattle, Washington, U.S., best known for its promotion of the pseudoscientific principle of intelligent design. As part of the Discovery Institute's Teach the Controversy campaign, the statement expresses skepticism about the ability of random mutations and natural selection to account for the complexity of life, and encourages careful examination of the evidence for "Darwinism", a term intelligent design proponents use to refer to evolution.
Paenarthrobacter ureafaciens KI72, popularly known as nylon-eating bacteria, is a strain of Paenarthrobacter ureafaciens that can digest certain by-products of nylon 6 manufacture. It uses a set of enzymes to digest nylon, popularly known as nylonase.
Objections to evolution have been raised since evolutionary ideas came to prominence in the 19th century. When Charles Darwin published his 1859 book On the Origin of Species, his theory of evolution initially met opposition from scientists with different theories, but eventually came to receive near-universal acceptance in the scientific community. The observation of evolutionary processes occurring has been uncontroversial among mainstream biologists since the 1940s.
This timeline of intelligent design outlines the major events in the development of intelligent design as presented and promoted by the intelligent design movement.
The Edge of Evolution: The Search for the Limits of Darwinism is an intelligent design book by Discovery Institute fellow Michael Behe, published by the Free Press in 2007. Behe argues that while evolution can produce changes within species, there is a limit to the ability of evolution to generate diversity, and this limit is somewhere between species and orders. On this basis, he says that known evolutionary mechanisms cannot be responsible for all the observed diversification from the last universal ancestor and the intervention of an intelligent designer can adequately account for much of the diversity of life. It is Behe's second intelligent design book, his first being Darwin's Black Box.
The Biologic Institute was a section of the Discovery Institute created to give the organization a facade of conducting biological research with the aim of producing experimental evidence of intelligent design creationism, funded by the Discovery Institute. It claimed offices in Redmond, Washington and laboratories in the Fremont neighborhood of Seattle, Washington. Instead Biologic Institute consisted solely of a rented office space in Redmond which is no longer in use for several years although the web domain is still renewed. The 'research' listed for the group consists mainly of random and often irrelevant works by Intelligent Design supporters going back to their graduate school years. Several are notably articles, books or internally published content from Discovery's 'BioComplexity' journal which is not a legitimate scientific journal.
Why Darwin Matters: The Case Against Intelligent Design is a 2006 book by Michael Shermer, an author, publisher, and historian of science. Shermer examines the theory of evolution and the arguments presented against it. He demonstrates that the theory is very robust and is based on a convergence of evidence from a number of different branches of science. The attacks against it are, for the most part, very simplistic and easily demolished. He discusses how evolution and other branches of science can coexist with religious beliefs. He describes how he and Darwin both started out as creationists and how their thinking changed over time. He examines current attitudes towards evolution and science in general. He finds that in many cases the problem people have is not with the facts about evolution but with their ideas of what it implies.
The relationship between intelligent design and science has been a contentious one. Intelligent design (ID) is presented by its proponents as science and claims to offer an alternative to evolution. The Discovery Institute, a politically conservative think tank and the leading proponent of intelligent design, launched a campaign entitled "Teach the Controversy", which claims that a controversy exists within the scientific community over evolution. The scientific community rejects intelligent design as a form of creationism, and the basic facts of evolution are not a matter of controversy in science.
Natural genetic engineering (NGE) is a class of process proposed by molecular biologist James A. Shapiro to account for novelty created in the course of biological evolution. Shapiro developed this work in several peer-reviewed publications from 1992 onwards, and later in his 2011 book Evolution: A View from the 21st Century, which has been updated with a second edition in 2022. He uses NGE to account for several proposed counterexamples to the central dogma of molecular biology. Shapiro drew from work as diverse as the adaptivity of the mammalian immune system, ciliate macronuclei and epigenetics. The work gained some measure of notoriety after being championed by proponents of Intelligent Design, despite Shapiro's explicit repudiation of that movement.
