OTUD1

Last updated
OTUD1
Available structures
PDB Ortholog search: PDBe RCSB
Identifiers
Aliases OTUD1 , DUBA7, OTDC1, OTU deubiquitinase 1
External IDs OMIM: 612022 MGI: 1918448 HomoloGene: 45953 GeneCards: OTUD1
Gene location (Human)
Ideogram human chromosome 10.svg
Chr. Chromosome 10 (human) [1]
Human chromosome 10 ideogram.svg
HSR 1996 II 3.5e.svg
Red rectangle 2x18.png
Band 10p12.2Start23,439,458 bp [1]
End23,442,390 bp [1]
Orthologs
SpeciesHumanMouse
Entrez

220213

71198

Ensembl

ENSG00000165312

n/a

UniProt

Q5VV17

Q9CUB6

RefSeq (mRNA)

NM_001145373

NM_027715

RefSeq (protein)

NP_001138845

NP_081991

Location (UCSC) Chr 10: 23.44 – 23.44 Mb n/a
PubMed search [2] [3]
Wikidata
View/Edit Human View/Edit Mouse

OTU deubiquitinase 1 is a protein that in humans is encoded by the OTUD1 gene. [4]

Contents

Function

Deubiquitinating enzymes (DUBs; see MIM 603478) are proteases that specifically cleave ubiquitin (MIM 191339) linkages, negating the action of ubiquitin ligases. DUBA7 belongs to a DUB subfamily characterized by an ovarian tumor (OTU) domain.

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References

  1. 1 2 3 GRCh38: Ensembl release 89: ENSG00000165312 - Ensembl, May 2017
  2. ↑ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  3. ↑ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ↑ "Entrez Gene: OTU deubiquitinase 1" . Retrieved 2016-03-13.

Further reading


This article incorporates text from the United States National Library of Medicine, which is in the public domain.


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