| Senator | Party | Term | Notes |
|---|
| William B. Nye | Democrat | January 3, 1967 – January 7, 1971 | Nye resigned in 1971 to take a seat under Governor John Gilligan. |
| John Poda | Democrat | January 13, 1971 – December 31, 1972 | Poda did not seek re-election in 1972. |
| David Headley | Democrat | January 3, 1973 – December 31, 1976 | Headley did not seek re-election in 1976. |
| Kenneth Cox | Democrat | January 3, 1977 – December 31, 1982 | Cox was redistricted out of his district in 1982 and did not seek re-election. |
| Marcus Roberto | Democrat | January 3, 1983 – December 17, 1986 | Roberto was redistricted to the 28th District in 1982. He died in 1986 while in office. |
| Bob Nettle | Democrat | January 2, 1987 – March 31, 1995 | Nettle resigned in 1995 prior to the expiration of his term. |
| Leigh Herington | Democrat | March 31, 1995 – August 31, 2003 | Herington resigned in 2003 to run for Portage County Court of Common Pleas. |
| Kimberly Zurz | Democrat | September 3, 2003 – January 28, 2007 | Zurz resigned in 2007 to work under Governor Ted Strickland. |
| Tom Sawyer | Democrat | February 20, 2007 – December 31, 2016 | Sawyer was term-limited in 2016. |
| Vernon Sykes | Democrat | January 3, 2017 – January 3, 2025 | Sykes was term-limited in 2024 |
| Casey Weinstein | Democrat | January 3, 2025 - present | Incumbent |
