U.S. Highway 266 (US-266) is an east–west United States highway. It is only 43 miles (69 km) long, and lies entirely within the state of Oklahoma. The highway no longer meets the former route of its parent, U.S. Highway 66, and is closely paralleled by Interstate 40, which replaced US-266 as the major east–west highway east of Oklahoma City during the 1960s.
U.S. Route 259 is a north–south spur of U.S. Route 59 that runs for 250 miles (400 km) through rural areas of northeast Texas and southeast Oklahoma. The highway's southern terminus is near Nacogdoches, Texas at an interchange with its parent route, US 59. Its northern terminus is in the Ouachita Mountains, about 15 miles (24 km) south of Heavener, Oklahoma where it reunites with U.S. 59. For most of its length, US 259 lies 30–50 miles (48–80 km) to the west of its parent route.
U.S. Route 270 (US 270) is a spur of US 70. It travels for 643 miles (1,035 km) from Liberal, Kansas at US 54 and US 83 to White Hall, Arkansas at Interstate 530 (I-530) and US 65. It travels through the states of Arkansas, Oklahoma, and Kansas. It travels through the cities of Oklahoma City, Oklahoma, Hot Springs, Arkansas, and McAlester, Oklahoma.
State Highway 6 runs from the Red River, the Texas–Oklahoma boundary, to northwest of Galveston, where it is known as the Old Galveston Highway. In Sugar Land and Missouri City, it is known as Alvin-Sugarland Road and runs perpendicular to I-69/US 59. In the Houston area, it runs north to FM 1960, then northwest along US Highway 290 to Hempstead, and south to Westheimer Road and Addicks, and is known as Addicks Satsuma Road. In the Bryan–College Station area, it is known as the Earl Rudder Freeway. In Hearne, it is known as Market Street. In Calvert, it is known as Main Street. For most of its length, SH 6 is not a limited-access road.
State Highway 97 is a 19.86-mile (31.96 km) state highway, maintained by the U.S. state of Oklahoma. It connects two towns in the northeast part of the state: Sapulpa and Sand Springs. Several communities of West Tulsa are along the road between these two towns, including Pretty Water, Allen, and Prattville.
State Highway 66 is a 192.7-mile (310.1 km) state highway in the U.S. state of Oklahoma, beginning at U.S. Highway 81 in El Reno and ending at U.S. Highway 60 near White Oak. The highway was designated in 1985 as a replacement for the decommissioned US-66. Although most of the highway follows Historic Route 66, the highway follows US-66's final alignment, joining Interstate 44 through Tulsa and Oklahoma City, while older versions of the route follow various city streets through both cities.
State Highway 9, abbreviated as SH-9, OK-9, or simply Highway 9, is a major east–west highway in the U.S. state of Oklahoma. Spanning across the central part of the state, SH-9 begins at the Texas state line near Madge, Oklahoma, and ends at the Arkansas state line near Fort Smith, Arkansas. State Highway 9 is a major highway around the Norman area. At 348.1 miles (560.2 km), SH-9 is Oklahoma's second-longest state highway.
State Highway 2, abbreviated SH-2 or OK-2, is a designation for two distinct highways maintained by the U.S. state of Oklahoma. Though they were once connected, the middle section of highway was concurrent with three different U.S. highways, so the middle section was decommissioned for reasons of redundancy.
State Highway 10 is a state highway in northeastern Oklahoma. It makes a 233.1 miles (375.1 km) crescent through the northeast corner of the state, running from SH-99 in Osage County to Interstate 40 (I-40) near Gore. It has two lettered spur routes.
State Highway 50 is a state highway in northwestern Oklahoma. The majority of the 37.7-mile (60.7 km) highway is in Woodward County, though the northernmost three miles (4.8 km) are in Woods County. SH-50 runs near two state parks and has a lettered spur that goes to each of them.
State Highway 101 is a 23.4 mile state highway in Sequoyah Co., Oklahoma, in the United States. It runs from US-59 north of Sallisaw to the Arkansas state line. After crossing the line, it becomes Highway 220.
State Highway 44 is a state highway in the western portion of the U.S. state of Oklahoma. It runs for 59.2 miles (95.3 km), beginning north of Blair in Greer County, and proceeding north to Butler in Custer County. It is not to be confused with Interstate 44. The highway has one lettered spur route, SH-44A.
State Highway 132, also known as SH-132, is a state highway in north-central Oklahoma. It connects State Highway 51 west of Hennessey to the Kansas state line near Manchester, and is 65.3 miles (105.1 km) long. It has no lettered spur routes.
State Highway 128 is a 9.81-mile-long (15.79 km) state highway in Le Flore County, Oklahoma. It connects U.S. Route 59 in Heavener to the Arkansas state line, where it becomes Arkansas Highway 28. It has no lettered spur routes.
State Highway 112 is a 24.6 mi (39.6 km) state highway in Le Flore County, Oklahoma. It connects Poteau to Arkoma. It has no lettered spur routes.
U.S. Highway 59 (US-59) heads along the eastern portion of the state of Oklahoma. US-59's 216.47-mile (348.37 km) route through Oklahoma takes it through the mountainous terrain of the eastern Oklahoma Ouachitas and Ozarks. US-59 serves several lakes and towns through Oklahoma's Green Country, including Grand Lake, a major recreation center. The route enters the state from Arkansas near Fogel, Arkansas, and ends at the Kansas state line south of Chetopa, Kansas.
State Highway 85 is a state highway in the northeastern part of the U.S. state of Oklahoma. The highway is 13.3 miles (21.4 km) long. SH-85 provides access to the northwest shore of Grand Lake, a major recreation center for northwest Oklahoma. SH-85 has one lettered spur highway, SH-85A.
U.S. Route 81 (US-81) is a north–south U.S. highway running through the central United States' Great Plains region, from Fort Worth, Texas to the U.S.–Canadian border at Pembina, North Dakota. A 229.28-mile (368.99 km) segment of the highway lies within the state of Oklahoma. US-81 crosses the Red River from Texas south of Terral, passing through several Oklahoma cities, such as Chickasha, El Reno, Kingfisher, and Enid, before entering Kansas north of Renfrow.
U.S. Route 412 is a U.S. highway in the south-central portion of the United States, connecting Springer, New Mexico to Columbia, Tennessee. A 504.11-mile (811.29 km) section of the highway crosses the state of Oklahoma, traversing the state from west to east. Entering the state southwest of Boise City, US-412 runs the length of the Oklahoma Panhandle and serves the northern portion of the state's main body, before leaving the state at West Siloam Springs. Along the way, the route serves many notable cities and towns, including Boise City, Guymon, Woodward, Enid, and the state's second-largest city, Tulsa.
U.S. Route 64 (US-64) is a U.S. highway running from the Four Corners area to the Outer Banks of North Carolina. Between these two points, the highway passes through the entire width of Oklahoma; a total of 591.17 miles (951.40 km) of US-64 lies in the state of Oklahoma. US-64 enters the state from New Mexico, crossing the line between the two states between Clayton, New Mexico, and Boise City in Cimarron County. The route runs the full length of the Oklahoma Panhandle, then serves the northernmost tier of counties in the main body of the state before dipping southeastward to Tulsa, the state's second-largest city. From Tulsa, the highway continues southeast, leaving Oklahoma just west of Fort Smith, Arkansas. In addition to Tulsa, US-64 serves fifteen Oklahoma counties and the cities of Guymon, Woodward, Enid, and Muskogee.
US 59 north of Howe 
AR 96 at the Arkansas state line
