PARP8

PARP8
Identifiers
Aliases	PARP8 , ARTD16, pART16, poly(ADP-ribose) polymerase family member 8
External IDs	MGI: 1098713 HomoloGene: 11621 GeneCards: PARP8
Gene location (Human) Chr. Chromosome 5 (human) [1] Band 5q11.1 Start 50,665,899 bp [1] End 50,846,519 bp [1]
Gene location (Mouse) Chr. Chromosome 13 (mouse) [2] Band 13 D2.3|13 65.32 cM Start 116,854,820 bp [2] End 117,025,537 bp [2]
RNA expression pattern More reference expression data
Gene ontology Molecular function • glycosyltransferase activity • NAD+ ADP-ribosyltransferase activity • transferase activity • protein ADP-ribosylase activity Cellular component • intracellular anatomical structure Biological process • metabolism • protein ADP-ribosylation • protein auto-ADP-ribosylation • protein mono-ADP-ribosylation Sources:Amigo / QuickGO
Orthologs
Species	Human	Mouse
Entrez	79668	52552
Ensembl	ENSG00000151883	ENSMUSG00000021725
UniProt	Q8N3A8	Q3UD82
RefSeq (mRNA)	NM_001178055 NM_001178056 NM_024615 NM_001331028	NM_001081009 NM_027272
RefSeq (protein)	NP_001171526 NP_001171527 NP_001317957 NP_078891	NP_001074478
Location (UCSC)	Chr 5: 50.67 – 50.85 Mb	Chr 13: 116.85 – 117.03 Mb
PubMed search	[3]	[4]
Wikidata
View/Edit Human View/Edit Mouse

Poly [ADP-ribose] polymerase 8 is an enzyme that in humans is encoded by the PARP8 gene. ^{[5] [6]}

References

1. GRCh38: Ensembl release 89: ENSG00000151883 - Ensembl, May 2017
2. GRCm38: Ensembl release 89: ENSMUSG00000021725 - Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. Ame JC, Spenlehauer C, de Murcia G (Jul 2004). "The PARP superfamily". BioEssays. 26 (8): 882–93. doi:10.1002/bies.20085. PMID   15273990. S2CID   25024719.
6. "Entrez Gene: PARP8 poly (ADP-ribose) polymerase family, member 8".

Further reading

• Maruyama K, Sugano S (1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides". Gene. 138 (1–2): 171–4. doi:10.1016/0378-1119(94)90802-8. PMID   8125298.
• Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, et al. (1997). "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library". Gene. 200 (1–2): 149–56. doi:10.1016/S0378-1119(97)00411-3. PMID   9373149.
• Hartley JL, Temple GF, Brasch MA (2001). "DNA cloning using in vitro site-specific recombination". Genome Res. 10 (11): 1788–95. doi:10.1101/gr.143000. PMC   310948 . PMID   11076863.
• Wiemann S, Weil B, Wellenreuther R, et al. (2001). "Toward a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs". Genome Res. 11 (3): 422–35. doi:10.1101/gr.GR1547R. PMC   311072 . PMID   11230166.
• Simpson JC, Wellenreuther R, Poustka A, et al. (2001). "Systematic subcellular localization of novel proteins identified by large-scale cDNA sequencing". EMBO Rep. 1 (3): 287–92. doi:10.1093/embo-reports/kvd058. PMC   1083732 . PMID   11256614.
• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi: 10.1073/pnas.242603899 . PMC   139241 . PMID   12477932.
• Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi: 10.1038/ng1285 . PMID   14702039.
• Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC   528928 . PMID   15489334.
• Wiemann S, Arlt D, Huber W, et al. (2004). "From ORFeome to biology: a functional genomics pipeline". Genome Res. 14 (10B): 2136–44. doi:10.1101/gr.2576704. PMC   528930 . PMID   15489336.
• Mehrle A, Rosenfelder H, Schupp I, et al. (2006). "The LIFEdb database in 2006". Nucleic Acids Res. 34 (Database issue): D415–8. doi:10.1093/nar/gkj139. PMC   1347501 . PMID   16381901.