PGM5

PGM5
Identifiers
Aliases	PGM5 , PGMRP, phosphoglucomutase 5
External IDs	OMIM: 600981; MGI: 1925668; HomoloGene: 74881; GeneCards: PGM5; OMA:PGM5 - orthologs
Gene location (Mouse) Chr. Chromosome 19 (mouse) [1] Band 19|19 B Start 24,660,380 bp [1] End 24,839,219 bp [1]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in saphenous vein seminal vesicula gastric mucosa urethra vena cava left uterine tube popliteal artery right ventricle nipple right coronary artery Top expressed in interventricular septum otolith organ utricle atrium vestibular membrane of cochlear duct myocardium of ventricle uterus aorta ascending aorta left colon More reference expression data BioGPS More reference expression data
Gene ontology Molecular function intramolecular transferase activity, phosphotransferases structural molecule activity metal ion binding phosphoglucomutase activity magnesium ion binding Cellular component cytoplasm cytosol intercalated disc focal adhesion cell-substrate junction adherens junction dystrophin-associated glycoprotein complex stress fiber cell junction spot adherens junction Z discdkac cytoplasmic side of plasma membrane sarcolemma costamere cytoskeleton Biological process organic substance metabolic process cell adhesion glycogen biosynthetic process glucose metabolic process galactose catabolic process carbohydrate metabolic process striated muscle tissue development myofibril assembly Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 5239 226041 Ensembl n/a ENSMUSG00000041731 UniProt Q15124 Q8BZF8 RefSeq (mRNA) NM_021965 NM_175013 RefSeq (protein) NP_068800 NP_778178 Location (UCSC) n/a Chr 19: 24.66 – 24.84 Mb PubMed search [2] [3]
Wikidata
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Phosphoglucomutase-like protein 5 is an enzyme that in humans is encoded by the PGM5 gene. ^{[4] [5] [6]}

References

1. GRCm38: Ensembl release 89: ENSMUSG00000041731 – Ensembl, May 2017
2. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
3. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. Edwards YH, Putt W, Fox M, Ives JH (Mar 1996). "A novel human phosphoglucomutase (PGM5) maps to the centromeric region of chromosome 9". Genomics. 30 (2): 350–3. doi:10.1006/geno.1995.9866. PMID   8586438.
5. Moiseeva EP, Belkin AM, Spurr NK, Koteliansky VE, Critchley DR (Jul 1996). "A novel dystrophin/utrophin-associated protein is an enzymatically inactive member of the phosphoglucomutase superfamily". Eur J Biochem. 235 (1–2): 103–13. doi: 10.1111/j.1432-1033.1996.00103.x . PMID   8631316.
6. "Entrez Gene: PGM5 phosphoglucomutase 5".

Further reading

• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi: 10.1073/pnas.242603899 . PMC   139241 . PMID   12477932.
• Wakayama Y, Inoue M, Kojima H, et al. (2000). "Aciculin and its relation to dystrophin: immunocytochemical studies in human normal and Duchenne dystrophy quadriceps muscles". Acta Neuropathol. 99 (6): 654–62. doi:10.1007/s004010051176. PMID   10867799. S2CID   20949507.
• Moiseeva EP, Critchley DR (1997). "Characterisation of the promoter which regulates expression of a phosphoglucomutase-related protein, a component of the dystrophin/utrophin cytoskeleton predominantly expressed in smooth muscle". Eur. J. Biochem. 248 (3): 634–43. doi:10.1111/j.1432-1033.1997.00634.x. PMID   9342213.
• Belkin AM, Klimanskaya IV, Lukashev ME, et al. (1994). "A novel phosphoglucomutase-related protein is concentrated in adherens junctions of muscle and nonmuscle cells". J. Cell Sci. 107 (1): 159–73. doi:10.1242/jcs.107.1.159. PMID   8175905.
• Belkin AM, Burridge K (1995). "Association of aciculin with dystrophin and utrophin". J. Biol. Chem. 270 (11): 6328–37. doi: 10.1074/jbc.270.11.6328 . PMID   7890770.
• Belkin AM, Burridge K (1995). "Localization of utrophin and aciculin at sites of cell-matrix and cell-cell adhesion in cultured cells". Exp. Cell Res. 221 (1): 132–40. doi:10.1006/excr.1995.1360. PMID   7589238.