PLSCR2

PLSCR2
Identifiers
Aliases	PLSCR2 , phospholipid scramblase 2
External IDs	OMIM: 607610 HomoloGene: 124471 GeneCards: PLSCR2
Gene location (Human)
Chr.	Chromosome 3 (human)
End	146,495,991 bp
RNA expression pattern
	Top expressed in
	sperm; ; monocyte; ; islet of Langerhans; ; body of pancreas; ; gallbladder; ; rectum; ; left uterine tube; ; kidney; ; right uterine tube; ; appendix;
	n/a
	More reference expression data
	n/a
Gene ontology
Molecular function	phospholipid scramblase activity ; calcium ion binding ; metal ion binding ;
Cellular component	integral component of membrane ; plasma membrane ; membrane ; nucleus ;
Biological process	plasma membrane phospholipid scrambling ;
	Sources:Amigo / QuickGO
Orthologs
	57047
	n/a
	ENSG00000163746
	n/a
	Q9NRY7
	n/a
	NM_001199978 ; NM_001199979 ; NM_020359
	n/a
	NP_001186907 ; NP_001186908 ; NP_065092
	n/a
	Wikidata
View/Edit Human

Last updated March 04, 2023

Phospholipid scramblase 2, also known as Ca²⁺-dependent phospholipid scramblase 2, is a protein that in humans is encoded by the PLSCR2 gene.^[3]^[4]

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References

1 2 3 GRCh38: Ensembl release 89: ENSG00000163746 - Ensembl, May 2017
↑ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ "Entrez Gene: phospholipid scramblase 2".
↑ Wiedmer T, Zhou Q, Kwoh DY, Sims PJ (July 2000). "Identification of three new members of the phospholipid scramblase gene family". Biochim. Biophys. Acta. 1467 (1): 244–53. doi: 10.1016/S0005-2736(00)00236-4 . PMID 10930526.

Strausberg RL, Feingold EA, Grouse LH, et al. (2002). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi: 10.1073/pnas.242603899 . PMC 139241 . PMID 12477932.
Sahu SK, Aradhyam GK, Gummadi SN (2009). "Calcium binding studies of peptides of human phospholipid scramblases 1 to 4 suggest that scramblases are new class of calcium binding proteins in the cell". Biochim. Biophys. Acta. 1790 (10): 1274–81. doi:10.1016/j.bbagen.2009.06.008. PMID 19540310.
Yu A, McMaster CR, Byers DM, et al. (2003). "Stimulation of phosphatidylserine biosynthesis and facilitation of UV-induced apoptosis in Chinese hamster ovary cells overexpressing phospholipid scramblase 1". J. Biol. Chem. 278 (11): 9706–14. doi: 10.1074/jbc.M204614200 . PMID 12509439.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928 . PMID 15489334.

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[refGRCh38Ensembl-1] 1 2 3 GRCh38: Ensembl release 89: ENSG00000163746 - Ensembl, May 2017

[2] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[entrez-3] "Entrez Gene: phospholipid scramblase 2".

[pmid10930526-4] Wiedmer T, Zhou Q, Kwoh DY, Sims PJ (July 2000). "Identification of three new members of the phospholipid scramblase gene family". Biochim. Biophys. Acta. 1467 (1): 244–53. doi: 10.1016/S0005-2736(00)00236-4 . PMID 10930526.

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PLSCR2

Contents

See also

Related Research Articles

References

Further reading