PPAPDC1A

PLPP4
Identifiers
Aliases	PLPP4 , DPPL2, PPAPDC1, PPAPDC1A, phospholipid phosphatase 4
External IDs	MGI: 2685936 HomoloGene: 38751 GeneCards: PLPP4
Gene location (Human)
Chr.	Chromosome 10 (human)
End	120,592,065 bp
Gene location (Mouse)
Chr.	Chromosome 7 (mouse)
End	128,993,136 bp
RNA expression pattern
	Top expressed in
	oocyte; ; secondary oocyte; ; hypothalamus; ; hippocampus proper; ; substantia nigra; ; amygdala; ; pons; ; stromal cell of endometrium; ; putamen; ; cingulate gyrus;
	Top expressed in
	olfactory bulb; ; hypothalamus; ; mesencephalon; ; cerebellum; ; cerebellar cortex; ; hippocampus proper; ; superior frontal gyrus; ; neural tube; ; urinary bladder; ; duodenum;
	More reference expression data
	n/a
Gene ontology
Molecular function	hydrolase activity ; phosphatidate phosphatase activity ; identical protein binding ; phosphatase activity ;
Cellular component	integral component of membrane ; plasma membrane ; integral component of plasma membrane ; membrane ;
Biological process	phospholipid metabolic process ; phospholipid dephosphorylation ; Fc-gamma receptor signaling pathway involved in phagocytosis ; signal transduction ; blastocyst hatching ;
	Sources:Amigo / QuickGO
Orthologs
	196051
	381925
	ENSG00000203805
	ENSMUSG00000070366
	Q5VZY2
	Q0VBU9
	NM_001030059 ; NM_001318166 ; NM_001318167 ; NM_001318168 ; NM_001318169
	NM_001080963
	NP_001025230 ; NP_001305095 ; NP_001305096 ; NP_001305097 ; NP_001305098
	NP_001074432
	Wikidata
View/Edit Human	View/Edit Mouse

Last updated October 18, 2022

Phosphatidate phosphatase PPAPDC1A also known as phosphatidic acid phosphatase type 2 domain containing 1A is an enzyme that in humans is encoded by the PPAPDC1A gene.^[5] PPAPDC1A has phosphatidate phosphatase activity.^[6]

Related Research Articles

b(0,+)-type amino acid transporter 1, also known as b(0,+)AT1, is a protein which in humans is encoded by the SLC7A9 gene.

Lipid phosphate phosphohydrolase 2 is an enzyme that in humans is encoded by the PPAP2C gene.

Myotubularin-related protein 3 is a protein that in humans is encoded by the MTMR3 gene.

Lipin-1 is a protein that in humans is encoded by the LPIN1 gene.

Tyrosine-protein phosphatase non-receptor type 4 is an enzyme that in humans is encoded by the PTPN4 gene.

Phosphatidate cytidylyltransferase 1 is an enzyme that in humans is encoded by the CDS1 gene.

Putative tyrosine-protein phosphatase auxilin is an enzyme that in humans is encoded by the DNAJC6 gene.

Dual specificity protein phosphatase 12 is an enzyme that in humans is encoded by the DUSP12 gene.

Collagen, type XXVIII, alpha 1 also known as COL28A1 is a protein that in humans is encoded by the COL28A1 gene. This protein belongs to a class of collagens that contain von Willebrand factor type A domains. The protein is encoded by the COL28A1 gene which contains 45 exons and is found of the p arm of chromosome 7.

Zinc finger and BTB domain containing 11 is a protein that in humans is encoded by the ZBTB11 gene.

Inositol monophosphatase 3 also known as inositol monophosphatase domain-containing protein 1 (IMPAD1) is an enzyme that in humans is encoded by the IMPAD1 gene.

Solute carrier family 7, member 14 is a protein that in humans is encoded by the SLC7A14 gene.

Forkhead box Q1 is a protein that in humans is encoded by the FOXQ1 gene.

Myotubularin related protein 12 is a protein that in humans is encoded by the MTMR12 gene.

Dual specificity phosphatase 8 is a protein that in humans is encoded by the DUSP8 gene.

3-hydroxyacyl-CoA dehydratase 2 is a protein that in humans is encoded by the HACD2 gene.

Solute carrier family 38 member 5 is a protein that in humans is encoded by the SLC38A5 gene.

Forkhead box S1 is a protein that in humans is encoded by the FOXS1 gene.

Protein phosphatase with EF-hand domain 2 is a protein that in humans is encoded by the PPEF2 gene.

Aldo-keto reductase family 1 member C2, also known as bile acid binding protein, 3α-hydroxysteroid dehydrogenase type 3, and dihydrodiol dehydrogenase type 2, is an enzyme that in humans is encoded by the AKR1C2 gene.

References

1 2 3 GRCh38: Ensembl release 89: ENSG00000203805 - Ensembl, May 2017
1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000070366 - Ensembl, May 2017
↑ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ "Entrez Gene: phosphatidic acid phosphatase type 2 domain containing 1A".
↑ Takeuchi M, Harigai M, Momohara S, Ball E, Abe J, Furuichi K, Kamatani N (September 2007). "Cloning and characterization of DPPL1 and DPPL2, representatives of a novel type of mammalian phosphatidate phosphatase". Gene. 399 (2): 174–80. doi:10.1016/j.gene.2007.05.009. PMID 17590538.

This article on a gene on human chromosome 10 is a stub. You can help Wikipedia by expanding it.

This page is based on this Wikipedia article
Text is available under the CC BY-SA 4.0 license; additional terms may apply.
Images, videos and audio are available under their respective licenses.

[refGRCh38Ensembl-1] 1 2 3 GRCh38: Ensembl release 89: ENSG00000203805 - Ensembl, May 2017

[refGRCm38Ensembl-2] 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000070366 - Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[entrez-5] "Entrez Gene: phosphatidic acid phosphatase type 2 domain containing 1A".

[pmid17590538-6] Takeuchi M, Harigai M, Momohara S, Ball E, Abe J, Furuichi K, Kamatani N (September 2007). "Cloning and characterization of DPPL1 and DPPL2, representatives of a novel type of mammalian phosphatidate phosphatase". Gene. 399 (2): 174–80. doi:10.1016/j.gene.2007.05.009. PMID 17590538.

[1]

[2]

[3]

[4]

[5]

[6]