PSG4

PSG4
Identifiers
Aliases	PSG4 , PSG9, PSBG-4, PSBG-9, pregnancy specific beta-1-glycoprotein 4
External IDs	OMIM: 176393 HomoloGene: 130509 GeneCards: PSG4
Gene location (Human)
Chr.	Chromosome 19 (human)
End	43,207,299 bp
RNA expression pattern
	Top expressed in
	placenta; ; tibialis anterior muscle; ; amniotic fluid; ; islet of Langerhans; ; skin of abdomen; ; palpebral conjunctiva; ; seminal vesicula; ; lower lobe of lung; ; kidney; ; muscle tissue;
	n/a
	More reference expression data
	n/a
Orthologs
	5672
	n/a
	ENSG00000243137
	n/a
	Q00888 ; Q96QL5 ; Q6P520
	n/a
	NM_001276495 ; NM_002780 ; NM_213633 ; NM_001316339
	n/a
NP_001263424 ; NP_001303268 ; NP_002771 ; NP_998798 ; NP_001263424.1 ;
	NP_001303268.1 ; NP_002771.2 ; NP_998798.1 ; NP_001303268.1
	n/a
	Wikidata
View/Edit Human

Last updated September 30, 2022

Pregnancy-specific beta-1-glycoprotein 4 is a protein that in humans is encoded by the PSG4 gene.^[3]^[4]

Related Research Articles

Carcinoembryonic antigen-related cell adhesion molecule 1 (CEACAM1) also known as CD66a, is a human glycoprotein, and a member of the carcinoembryonic antigen (CEA) gene family.

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Zinc-alpha-2-glycoprotein is a protein that in humans is encoded by the AZGP1 gene.

Beta-1,4-galactosyltransferase 1 is an enzyme that in humans is encoded by the B4GALT1 gene.

Pregnancy specific beta-1-glycoprotein 1 (PSBG-1) also known as CD66f, is a protein that in humans is encoded by the PSG1 gene and is a member of the carcinoembryonic antigen (CEA) gene family. Pregnancy-specific glycoproteins (PSGs) are a complex consisting of carbohydrate and protein, which is present in the mammalian body specifically during pregnancy. This glycoprotein is the most abundant protein found in the maternal bloodstream during the later stages of pregnancy and it is of vital importance in fetal development. The PSG functions primarily as an immunomodulator to protect the growing fetus.

Alpha-(1,3)-fucosyltransferase is an enzyme that in humans is encoded by the FUT6 gene.

Pregnancy-specific beta-1-glycoprotein 9 is a protein that in humans is encoded by the PSG9 gene.

Carcinoembryonic antigen-related cell adhesion molecule 3 (CEACAM3) also known as CD66d, is a member of the carcinoembryonic antigen (CEA) gene family..

Pregnancy-specific beta-1-glycoprotein 3 is a protein that in humans is encoded by the PSG3 gene.

NEDD9-interacting protein with calponin homology and LIM domains is a protein that in humans is encoded by the MICAL1 gene.

Carcinoembryonic antigen-related cell adhesion molecule 8 (CEACAM8) also known as CD66b, is a member of the carcinoembryonic antigen (CEA) gene family. Its main function is cell adhesion, cell migration, and pathogen binding.

Pregnancy-specific beta-1-glycoprotein 5 is a protein that in humans is encoded by the PSG5 gene.

Carcinoembryonic antigen-related cell adhesion molecule 7 is a protein that in humans is encoded by the CEACAM7 gene.

Alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase is an enzyme that in humans is encoded by the MGAT1 gene.

Pregnancy-specific beta-1-glycoprotein 6 is a protein that in humans is encoded by the PSG6 gene.

High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8B is an enzyme that in humans is encoded by the PDE8B gene.

Pregnancy-specific beta-1-glycoprotein 10 is a protein that in humans is encoded by the PSG10 gene.

Carcinoembryonic antigen-related cell adhesion molecule 5 (CEACAM5) also known as CD66e, is a member of the carcinoembryonic antigen (CEA) gene family.

Zinc finger protein 33A is a protein that in humans is encoded by the ZNF33A gene.

References

1 2 3 GRCh38: Ensembl release 89: ENSG00000243137 - Ensembl, May 2017
↑ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ Zimmermann W, Weiss M, Thompson JA (Oct 1989). "cDNA cloning demonstrates the expression of pregnancy-specific glycoprotein genes, a subgroup of the carcinoembryonic antigen gene family, in fetal liver". Biochem Biophys Res Commun. 163 (3): 1197–209. doi:10.1016/0006-291X(89)91105-4. PMID 2783133.
↑ "Entrez Gene: PSG4 pregnancy specific beta-1-glycoprotein 4".

Thompson J, Koumari R, Wagner K, et al. (1990). "The human pregnancy-specific glycoprotein genes are tightly linked on the long arm of chromosome 19 and are coordinately expressed". Biochem. Biophys. Res. Commun. 167 (2): 848–59. CiteSeerX 10.1.1.655.1870 . doi:10.1016/0006-291X(90)92103-7. PMID 1690992.
Chan WY, Zheng QX, McMahon J, Tease LA (1991). "Characterization of new members of the pregnancy-specific beta 1-glycoprotein family". Mol. Cell. Biochem. 106 (2): 161–70. doi:10.1007/BF00230182. PMID 1922019. S2CID 21581759.
Barnett TR, Pickle W, Elting JJ (1991). "Characterization of two new members of the pregnancy-specific beta 1-glycoprotein family from the myeloid cell line KG-1 and suggestion of two distinct classes of transcription unit". Biochemistry. 29 (44): 10213–8. doi:10.1021/bi00496a009. PMID 2271648.
"The human pregnancy-specific glycoprotein genes are tightly linked on the long arm of chromosome 19 and are coordinately expressed". Biochem. Biophys. Res. Commun. 168 (3): 1325–1327. 1990. doi:10.1016/0006-291X(90)91174-Q. PMID 2346490.
Thompson JA, Mauch EM, Chen FS, et al. (1989). "Analysis of the size of the carcinoembryonic antigen (CEA) gene family: isolation and sequencing of N-terminal domain exons". Biochem. Biophys. Res. Commun. 158 (3): 996–1004. CiteSeerX 10.1.1.657.2780 . doi:10.1016/0006-291X(89)92821-0. PMID 2537643.
Chan WY, Borjigin J, Zheng QX, Shupert WL (1988). "Characterization of cDNA encoding human pregnancy-specific beta 1-glycoprotein from placenta and extraplacental tissues and their comparison with carcinoembryonic antigen". DNA. 7 (8): 545–55. doi:10.1089/dna.1.1988.7.545. PMID 3180995.
Teglund S, Zhou GQ, Hammarström S (1995). "Characterization of cDNA encoding novel pregnancy-specific glycoprotein variants". Biochem. Biophys. Res. Commun. 211 (2): 656–64. doi:10.1006/bbrc.1995.1862. PMID 7794280.
Olsen A, Teglund S, Nelson D, et al. (1995). "Gene organization of the pregnancy-specific glycoprotein region on human chromosome 19: assembly and analysis of a 700-kb cosmid contig spanning the region". Genomics. 23 (3): 659–68. doi:10.1006/geno.1994.1555. PMID 7851895.
Kimoto Y (1998). "A single human cell expresses all messenger ribonucleic acids: the arrow of time in a cell". Mol. Gen. Genet. 258 (3): 233–9. doi:10.1007/s004380050727. PMID 9645429. S2CID 11818700.
Dias Neto E, Correa RG, Verjovski-Almeida S, et al. (2000). "Shotgun sequencing of the human transcriptome with ORF expressed sequence tags". Proc. Natl. Acad. Sci. U.S.A. 97 (7): 3491–6. Bibcode:2000PNAS...97.3491D. doi: 10.1073/pnas.97.7.3491 . PMC 16267 . PMID 10737800.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi: 10.1073/pnas.242603899 . PMC 139241 . PMID 12477932.

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[refGRCh38Ensembl-1] 1 2 3 GRCh38: Ensembl release 89: ENSG00000243137 - Ensembl, May 2017

[2] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid2783133-3] Zimmermann W, Weiss M, Thompson JA (Oct 1989). "cDNA cloning demonstrates the expression of pregnancy-specific glycoprotein genes, a subgroup of the carcinoembryonic antigen gene family, in fetal liver". Biochem Biophys Res Commun. 163 (3): 1197–209. doi:10.1016/0006-291X(89)91105-4. PMID 2783133.

[entrez-4] "Entrez Gene: PSG4 pregnancy specific beta-1-glycoprotein 4".

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PSG4

Related Research Articles

References

Further reading