PSG5

PSG5
Identifiers
Aliases	PSG5 , FL-NCA-3, PSG, pregnancy specific beta-1-glycoprotein 5
External IDs	OMIM: 176394; GeneCards: PSG5; OMA:PSG5 - orthologs
Gene location (Human) Chr. Chromosome 19 (human) [1] Band 19q13.31 Start 43,166,256 bp [1] End 43,186,536 bp [1]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in placenta decidua buccal mucosa cell testicle stromal cell of endometrium endothelial cell gonad cardia germ cell male germ cell n/a More reference expression data BioGPS More reference expression data
Gene ontology Molecular function protein binding Cellular component extracellular region Biological process female pregnancy Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 5673 n/a Ensembl ENSG00000204941 n/a UniProt Q15238 n/a RefSeq (mRNA) NM_001130014 NM_002781 n/a RefSeq (protein) NP_001123486 NP_002772 n/a Location (UCSC) Chr 19: 43.17 – 43.19 Mb n/a PubMed search [2] n/a
Wikidata
View/Edit Human

Pregnancy-specific beta-1-glycoprotein 5 is a protein that in humans is encoded by the PSG5 gene. ^{[3] [4]}

References

1. GRCh38: Ensembl release 89: ENSG00000204941 – Ensembl, May 2017
2. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
3. Khan WN, Hammarstrom S (Jul 1989). "Carcinoembryonic antigen gene family: molecular cloning of cDNA for a PS beta G/FL-NCA glycoprotein with a novel domain arrangement". Biochem Biophys Res Commun. 161 (2): 525–35. doi:10.1016/0006-291X(89)92631-4. PMID   2735907.
4. "Entrez Gene: PSG5 pregnancy specific beta-1-glycoprotein 5".

Further reading

• Panzetta-Dutari GM, Bocco JL, Reimund B, et al. (1993). "Nucleotide sequence of a pregnancy-specific beta 1 glycoprotein gene family member. Identification of a functional promoter region and several putative regulatory sequences". Mol. Biol. Rep. 16 (4): 255–62. doi:10.1007/BF00419665. PMID   1454058. S2CID   7303287.
• Thompson J, Koumari R, Wagner K, et al. (1990). "The human pregnancy-specific glycoprotein genes are tightly linked on the long arm of chromosome 19 and are coordinately expressed". Biochem. Biophys. Res. Commun. 167 (2): 848–59. CiteSeerX   10.1.1.655.1870 . doi:10.1016/0006-291X(90)92103-7. PMID   1690992.
• Chan WY, Zheng QX, McMahon J, Tease LA (1991). "Characterization of new members of the pregnancy-specific beta 1-glycoprotein family". Mol. Cell. Biochem. 106 (2): 161–70. doi:10.1007/BF00230182. PMID   1922019. S2CID   21581759.
• Thompson JA, Mauch EM, Chen FS, et al. (1989). "Analysis of the size of the carcinoembryonic antigen (CEA) gene family: isolation and sequencing of N-terminal domain exons". Biochem. Biophys. Res. Commun. 158 (3): 996–1004. CiteSeerX   10.1.1.657.2780 . doi:10.1016/0006-291X(89)92821-0. PMID   2537643.
• Oikawa S, Inuzuka C, Kuroki M, et al. (1989). "A pregnancy-specific beta 1-glycoprotein, a CEA gene family member, expressed in a human promyelocytic leukemia cell line, HL-60: structures of protein, mRNA and gene". Biochem. Biophys. Res. Commun. 163 (2): 1021–31. doi:10.1016/0006-291X(89)92324-3. PMID   2789512.
• Teglund S, Zhou GQ, Hammarström S (1995). "Characterization of cDNA encoding novel pregnancy-specific glycoprotein variants". Biochem. Biophys. Res. Commun. 211 (2): 656–64. doi:10.1006/bbrc.1995.1862. PMID   7794280.
• Olsen A, Teglund S, Nelson D, et al. (1995). "Gene organization of the pregnancy-specific glycoprotein region on human chromosome 19: assembly and analysis of a 700-kb cosmid contig spanning the region". Genomics. 23 (3): 659–68. doi:10.1006/geno.1994.1555. PMID   7851895.
• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi: 10.1073/pnas.242603899 . PMC   139241 . PMID   12477932.
• Colland F, Jacq X, Trouplin V, et al. (2004). "Functional Proteomics Mapping of a Human Signaling Pathway". Genome Res. 14 (7): 1324–32. doi:10.1101/gr.2334104. PMC   442148 . PMID   15231748.
• Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC   528928 . PMID   15489334.
• Rual JF, Venkatesan K, Hao T, et al. (2005). "Towards a proteome-scale map of the human protein-protein interaction network". Nature. 437 (7062): 1173–8. Bibcode:2005Natur.437.1173R. doi:10.1038/nature04209. PMID   16189514. S2CID   4427026.
• Blanchon L, Nores R, Gallot D, et al. (2006). "Activation of the human pregnancy-specific glycoprotein PSG-5 promoter by KLF4 and Sp1". Biochem. Biophys. Res. Commun. 343 (3): 745–53. doi:10.1016/j.bbrc.2006.03.032. PMID   16563348.
• Okazaki S, Sekizawa A, Purwosunu Y, et al. (2007). "Placenta-derived, cellular messenger RNA expression in the maternal blood of preeclamptic women". Obstetrics and Gynecology. 110 (5): 1130–6. doi:10.1097/01.AOG.0000286761.11436.67. PMID   17978129. S2CID   24566450.